Walking A Tightrope

In an event that attracted worldwide atten-tion, U.S.President Donald Trumpand Russian President Vladimir Putin held their first official meeting in Helsinki, Finland, on July 16. The two leaders previously met informally during the Group of 20 Summit and the APEC Economic Leaders' Meeting last year in Germany and Viet Nam.     

The impact of increasing vs. decreasing harassing behaviours on perceptions of hypothetical instances of repeated sexual harassment

ABSTRACT

Sexual harassment is a traditionally underreported crime. One factor that might affect perceptions and willingness to report harassment is its occurrence over time: harassing behaviours that gradually increase or decrease in severity over time might impact its perception. In the present research, 177 female participants read a series of daily scenarios about increasing, decreasing, or steady harassment, and completed measures regarding their perceptions of and willingness to report it. Participants displayed increases and decreases in negative reactions as harassment increased and decreased, respectively, suggesting that each instance of sexual harassment is interpreted independently of earlier harassing behaviours, and that early, strongly harassing behaviours have little impact on how subsequent instances of harassment are perceived. This explanation is supported by the similar ratings in the midpoint (day 4) of the scenario series, regardless of whether harassment was increasing or decreasing.     

Vice-Premier Li Hsien-Nien gives Banquet in name of Premier Chou En-Lai for Madame Marcos

This article provides empirical light on the debate concerning whether manufacturing firms in China are becoming major innovators. Based on an innovation survey carried out in Jiangsu Province, the article finds that most firms engage in innovative activities but these are mainly of an incremental nature. Radical innovation, as a proportion of sales, is relatively low if compared internationally. Innovation in China is mainly to catch-up and is novel relative to the firm and the domestic market. A small proportion of innovation is new to the world. Intensity and productivity indicators suggest that small, foreign and textile firms are leading innovative efforts. Firms innovate to improve their general competitiveness, including improving product quality and extending market share, obtain income from technology and defend themselves from research and development expenditure by competitors. Innovators value significantly more than non-innovators the range of innovative objectives they seek to achieve. The main obstacles to innovation arise from technical and marketing weaknesses; the perception of these obstacles varies widely between radical innovators and non-innovators. The article concludes that while innovative activities are emerging it will still take some time for China to have a major role in the international division of innovative labour.     

论毛泽东法律监督思想的“群众路线”内核

毛泽东法律监督思想作为毛泽东思想的重要组成部分,是中国特色社会主义法律体系的重要指导思想。在毛泽东法律监督思想中,贯穿始终的"群众路线"内核,是对马克思、恩格斯、列宁法律监督思想"人民性"的继承和超越,这对当下中国特色社会主义建设和法律监督工作具有非常重要的指导意义。     

氯硝安定在生物体内的代谢

目的推测氯硝安定在生物体内的主要代谢方式,检测其代谢产物。方法取5只Wistar大鼠,连续3d给每只大鼠灌胃氯硝安定（剂量分别为1、2、2mg）,收集灌胃后24h内尿液;给3只大鼠各灌胃2mg氯硝安定,2h后处死,取血液和肝组织等检材;收集3名口服5mg氯硝安定的志愿者24h内尿液。分别对不同检材进行处理后,气相色谱/质谱联用（GC/MS）检测。结果在大鼠阳性尿液和志愿者阳性尿液中,均检出7-乙酰氨基氯硝安定和7-氨基氯硝基安定;在大鼠血液中,主要检出氯硝安定和7-氨基氯硝基安定;在大鼠肝组织中,主要检出7-乙酰氨基氯硝安定,还有少量7-氨基氯硝安定和氯硝安定。结论氯硝安定进入生物体后,其7位硝基被还原为氨基,氨基接着被乙酰化,形成7-氨基氯硝基安定和7-乙酰氨基氯硝安定代谢物,其中7-乙酰氨基氯硝安定为主要代谢物。     

Immunohistochemical detection of CCR2 and CX3CR1 in sepsis-induced lung injury

Sepsis is a systemic inflammatory disease with high mortality. In the present study, we immunohistochemically examined CCR2 and CX3CR1 expression in sepsis-induced lung injury, and discussed its availability for the postmortem diagnosis of sepsis. Lung samples were obtained from different lung lobes of nine sepsis and eight control cases with postmortem intervals between 12 and 48 h. Immunohistochemically, mononuclear cells recruited into the lungs expressed CCR2 and CX3CR1 in both sepsis and non-septic groups. In double-color immunofluorescence analysis, CCR2- or CX3CR1-positive cells could be identified as CD68-positive macrophages. Moreover, most of CD68-positive macrophages expressed both CCR2 and CX3CR1. Morphometrically, the average of CCR2- and CX3CR1-positive macrophages was significantly increased in sepsis group, compared with control group (sepsis vs. control: 41.6 ± 1.3% vs. 8.0 ± 0.4% in CCR2; 36.2 ± 1.3% vs. 9.2 ± 0.4% in CX3CR1). These observations implied that CCR2- or CX3CR1-positive macrophages were recruited into the lungs under several pathological conditions. In particular, their recruitment might be more evident in sepsis. Moreover, from the forensic aspects, immunohistochemical detection of CCR2 and CX3CR1 expression in the lungs can be considered as valuable diagnostic tools for the postmortem diagnosis of sepsis.     

加强思想道德修养做遵纪守法的表率

反思一些党员干部违纪违法问题,教训是极其深刻的。我们既为一个个受党教育多年的领导干部堕落而痛惜,又为他们大肆受贿敛财的违纪违法事实而震惊。他们为何栽倒在金钱面前？留给我们一些什么深刻的警示和教训呢？我们如何把握自己,避免重蹈覆辙呢？我认为起码要做到“三有”、“一不能有”。     

Analysis of sensitivity and specificity: precise recognition of neutrophils during regeneration of contused skeletal muscle in rats

In this report, we applied the TissueFAXS 200 digital pathological analysis system to rapidly and accurately identify neutrophils during regeneration of contused skeletal muscle, and to provide information for follow-up studies on neutrophils to estimate wound age. Rat injury model was established, and skeletal muscle samples were obtained from the control group and contusion groups at 1, 1.5, 2, 3, 4, and 6 h, as well as at 1, 3, 5, and 15 d post-injury (n = 5 per group). The expression of nuclei and neutrophils was detected by hematoxylin and eosin (HE) staining and immunohistochemical (IHC) staining. A total of 20 injury site areas of 0.25 mm² (0.5 mm × 0.5 mm) were then randomly selected at all time points. A TissueFAXS 200 digital pathological analysis system was used to identify the positive and negative numbers. Knowledge of five professional medical workers were considered the gold standard to measure the false positive rate (FPR), false negative rate (FNR), sensitivity, specificity, and area under the curve (AUC) of receiver operating characteristic (ROC) curves. As a result, with a staining area of neutrophils from 8 µm² to 15 µm², the FPR was 4.28%–12.14%, the FNR was 12.42%–64.08%, the sensitivity was 35.92%–87.58%, the specificity was 87.86%–95.72%, the Youden index was 0.316–0.754, the accuracy was 82.80%–88.30%, and the AUC was 0.771–0.826. The AUC was largest when the cut-off value of the staining area was 12 µm². Our results show that this software-based method is more accurate than the human eye in evaluating neutrophil infiltration. Based on the sensitivity and specificity, neutrophils can be accurately identified during regeneration of contused skeletal muscle. The TissueFAXS 200 digital pathological analysis system can also be used to optimize conditions for different cell types under various injury conditions to determine the optimal cut-off value of the staining area and provide optimal conditions for further study. Furthermore, it will provide evidence for forensic pathology cases.