东南沿海劳动密集型企业西移的构想

李嘉图的比较成本理论对东南沿海的劳动密集型企业向西部地区转移具有重要指导作用.根据这一理论及中国的特殊国情--地域辽阔、区域层次复杂,设想把东南沿海劳动密集型企业西移,并从现实条件以及战略意义方面论证"西移"的构想是可行的,而且它对东南沿海和西部地区来说都存在"双赢".     

马克思主义民族发展理论在当代中国的实践与创新

民族发展理论是马克思主义民族理论的重要组成部分。新中国成立后,中国共产党和中国政府在社会主义革命和建设的实践中。继承和发展了马克思主义民族发展理论,经历了以政治平等为特征的发展理论——以经济建设为中心的发展理论——全面协调发展理论的演变过程,形成了具有中国特色的民族发展理论,极大地促进了少数民族现代化建设。     

基于大规模定制思想的高等教育培养模式研究

本文从有关概念出发,分析了教育的标准化和个性化,及两者之间的矛盾。借鉴制造业的“大规模定制”思想,提出了教育大规模定制的培养模式,展开了相关的讨论,认为客户定制是关键,模块化的课程结构是教育大规模定制的基础。     

太平天国的女子教育浅探

太平天国的女子教育形式主要有:营中教育、馆中教育、宫中教育和社会教育.太平天国的女子教育有一定成效,但其在实质上并没有反应出男女平等思想,太平天国的领导们也不具有真正的妇女解放的意识.     

新中国成立以来我军马克思主义信仰培育的主要历史经验

新中国成立以来,我军马克思主义信仰培育的主要历史经验有：始终坚持和完善党对军队的绝对领导,为军人的马克思主义信仰培育提供组织保证;坚持物质激励与精神激励相结合,坚持正确的义利导向;重视军营文化建设,为军人马克思主义信仰培育营造良好环境;积极开创社会主义建设新局面,为培育马克思主义信仰提供物质基础与现实动力;坚实推进马克思主义教育,培育官兵的马克思主义信仰自觉;坚定开展反腐倡廉建设;坚持以德治军与依法治军相结合,为马克思主义信仰培育提供世俗规范和依托。     

开放式基金业绩实证研究

分析评价开放式基金业绩,是一个现实而有意义的课题.其中的实证设计直接涉及如下主要因素:样本基金的选择、基准组合的选取、无风险利率和基金周收益率的计算、数据来源及应用软件的确定等.在此基础上,通过运用收益率评价法和风险调整收益法,对所选16只样本基金2005年和2006年的业绩进行对比研究后发现:样本基金的业绩与证券市场行情密切相关,受到股票市场环境的主导性影响;这种主导性影响主要体现在对开放式基金投资收益和风险的影响上.因此,研究我国开放式基金业绩应密切联系其所处的证券市场环境.     

浅析课程远程辅导与面授技术

现代远程教育飞速发展,其中课程远程辅导与面授技术的研究和应用在远程教育中已显得越来越重要.通过加强面授导学和网络导学,课程辅导教师应担当起组织者、指导者、开发者等多重角色,学生应加强自主与协作学习,采取师生交互行为策略有效应用等措施促进课程远程辅导与面授技术有效整合,从而提高远程教育的绩效,促进其实现可持续发展.     

Investigation on the genetic-inconsistent paternity cases using the MiSeq FGx system

Mutations might challenge the paternity index calculation in forensic identification. While many studies have focussed on the autosomal short tandem repeats (A-STR), the mutation status of sex chromosomes and single nucleotide polymorphism (SNP) remain blank. Next generation sequencing (NGS), known as high throughput and large sequence polymorphism, is a promising tool for forensic genetics. To describe the mutation landscapes in the paternity cases with genetic inconsistencies, a total of 63 parentage confirmed paternity cases contained at least one mismatched locus have been collected. The mutations were subsequently evaluated using Verogen’s MPS ForenSeq^TM DNA Signature Kit and a microsatellite instability (MSI) detection kit. The result showed 98.41% (62/63) of the cases had no additional autosomal mutations even when the number of A-STRs increased to 27. As for the sex chromosomes, about 11.11% (7/63) of the cases exhibited either X-STR or Y-STR mutations. D2S1338, FGA and Penta E were the most frequent altered STRs, which suggested they might be the mutation hotspots. In addition, a male with sex chromosome abnormality was observed accidently, whose genotype might be 47, XXY, rather than MSI. Nearly 56.90% of the STR loci possessed isoalleles, which might result in higher STR polymorphisms. No Mendelian incompatibility was detected among the SNP markers, which indicated that SNP was a more reliable genetic marker in the genetic-inconsistent paternity cases.Supplemental data for this article is available online at https://doi.org/10.1080/20961790.2021.2009631 .     

关于我国石油企业社会责任的思考

构建民主法治、公平正义、诚信友爱、充满活力、安定有序、人与自然和谐相处的社会主义和谐社会,是党的十六届四中全会提出的一个重要命题.我国石油企业作为关系国计民生的特大型骨干企业,应当立足大局,着眼长远,在履行经济责任和政治责任的同时,全面履行好企业的社会责任,实现企业与社会的共同和谐.     

Analysis of sensitivity and specificity: precise recognition of neutrophils during regeneration of contused skeletal muscle in rats

In this report, we applied the TissueFAXS 200 digital pathological analysis system to rapidly and accurately identify neutrophils during regeneration of contused skeletal muscle, and to provide information for follow-up studies on neutrophils to estimate wound age. Rat injury model was established, and skeletal muscle samples were obtained from the control group and contusion groups at 1, 1.5, 2, 3, 4, and 6 h, as well as at 1, 3, 5, and 15 d post-injury (n = 5 per group). The expression of nuclei and neutrophils was detected by hematoxylin and eosin (HE) staining and immunohistochemical (IHC) staining. A total of 20 injury site areas of 0.25 mm² (0.5 mm × 0.5 mm) were then randomly selected at all time points. A TissueFAXS 200 digital pathological analysis system was used to identify the positive and negative numbers. Knowledge of five professional medical workers were considered the gold standard to measure the false positive rate (FPR), false negative rate (FNR), sensitivity, specificity, and area under the curve (AUC) of receiver operating characteristic (ROC) curves. As a result, with a staining area of neutrophils from 8 µm² to 15 µm², the FPR was 4.28%–12.14%, the FNR was 12.42%–64.08%, the sensitivity was 35.92%–87.58%, the specificity was 87.86%–95.72%, the Youden index was 0.316–0.754, the accuracy was 82.80%–88.30%, and the AUC was 0.771–0.826. The AUC was largest when the cut-off value of the staining area was 12 µm². Our results show that this software-based method is more accurate than the human eye in evaluating neutrophil infiltration. Based on the sensitivity and specificity, neutrophils can be accurately identified during regeneration of contused skeletal muscle. The TissueFAXS 200 digital pathological analysis system can also be used to optimize conditions for different cell types under various injury conditions to determine the optimal cut-off value of the staining area and provide optimal conditions for further study. Furthermore, it will provide evidence for forensic pathology cases.