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161.
Gamma-Hydroxybutyric acid (GHB) is a CNS depressant that has been abused recreationally for its purported euphoric and relaxation effects and for the purposes of drug facilitated sexual assault due to its sedative and amnesic effects at higher doses. The dramatic increase in the abuse of GHB and association in criminal investigations over the past decade has created the need for forensic laboratories to develop analytical methods to detect GHB in a variety of matrices. The method developed in this work used solid-phase microextraction (SPME) to extract GHB from aqueous samples followed by on-fiber derivatization and analysis by gas chromatography/mass spectrometry (GC/MS). This method detected GHB in aqueous matrices with good sensitivity, high precision, excellent linearity from 0.01 mg/mL to 0.25 mg/mL, and without the need for sample manipulation that could cause interconversion between GHB and its lactone, GBL. The method was successfully applied for detection of GHB in spiked water and beverage samples. 相似文献
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Modelling the relationship between counter‐knowledge and open‐mindedness for policy development 下载免费PDF全文
Pedro‐José Martínez‐Ortiz Sandra Moffett Juan‐Gabriel Cegarra‐Navarro Fernando A. López Hernández 《Journal of Public Affairs (14723891)》2017,17(3)
Counter‐knowledge refers to flaws in citizens' mental models arising from utilization of rumours, inappropriate knowledge structures, outdated routines or procedures. When counter‐knowledge is applied to civil servants, it may result in problems of efficiency, equity and motivation. This paper examines the relationship between counter‐knowledge and open‐mindedness to model a framework for improving city marketing and policy development. This study tested two measurement models. While the theoretical model represents the effect of counter‐knowledge on city marketing and that the latter has a negative effect on open‐mindedness, the alternative model involves that counter‐knowledge has a positive indirect impact on open‐mindedness. These relationships are examined through an empirical investigation of 203 Spanish city halls. The results show a potential positive indirect effect of counter‐knowledge on open‐mindedness through city marketing programmes. This paper clarifies the existing literature, which tries to contribute to the discussion of city marketing, and helps us to obtain meaning out of the relationship between counter‐knowledge, city marketing and open‐mindedness. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
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Democracy may well be the primary virtue of political systems. Yet European politics is marked by a democracy deficit that will not disappear spontaneously. While legal and political theory on this issue is dominated by supporters of civic institutionalism and constitutional republicanism, liberal nationalists seem to be split. They justify the civic nationhood of member states, but they shrink away from the idea of a European people. This essay claims that a quasi-national conception of European identity can be conducive to the rise of a democratic political union of Europe. It discusses the mechanisms and rules for Europeanization of the sense of equal dignity and solidarity. This approach to supranational identity is explicitly instrumental and orientated towards the long run. However, the main liberal objections against it can be countered. 相似文献
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José Guillermo Pastrano 《The Journal of peasant studies》2013,40(4):688-719
Migrant poverty resulted from the bureaucratization of Mexicans as a cheap source of labor for the Texas cotton industry from 1910 to 1930. State and federal employment programs and policies designed to maintain an organized and efficient labor market bureaucratized the divisions of labor that segregated Mexicans in seasonal low-wage agricultural work. While the implementation of labor legislation solved the temporary labor needs of large-scale cotton farmers, it exacerbated the working and living conditions of Mexican migratory workers. The welfare of Mexican migrants worsened as state managers integrated the recruitment and distribution of this labor force into the organizational structure of the Texas cotton industry. 相似文献
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