Parental Depressive Feelings, Parental Support, and the Serotonin Transporter Gene as Predictors of Adolescent Depressive Feelings: A Latent Growth Curve Analysis

Parental support and parental depressive feelings are found to be associated with depressive feelings in adolescent boys and girls, but results are inconsistent. In addition, the 5-HTTLPR genotype has been found to interact with environmental stressors in predicting adolescents?? depressive feelings, but this has not been examined longitudinally. Therefore, the present study examined the relationships between parental support, parental depressive feelings, and adolescent depressive feelings. In addition, the relationships between the 5-HTTLPR genotype and adolescent depressive feelings were explored, as well as gene-environment interactions. Adolescents (N = 306; Girls = 53.3%; M _{age T1} = 13.4) filled out questionnaires at five annual waves and provided saliva samples for DNA. Latent growth curve modelling (LGCM) was used to examine the baseline level and the change in depressive feelings over time. Maternal support was related to baseline levels of depressive feelings in girls, whereas paternal support was related to baseline levels in boys. Paternal depressive feelings were only related to boys?? depressive feelings at baseline, and maternal depressive feelings were not related to any outcome measures. Furthermore, no associations were found between 5-HTTLPR genotype and adolescent depressive feelings, and no gene-environment interactions emerged. Limitations of the study and implications of the findings are discussed.     

On the use of IRMS in forensic science: proposals for a methodological approach

The flourishing number of publications on the use of isotope ratio mass spectrometry (IRMS) in forensic science denotes the enthusiasm and the attraction generated by this technology. IRMS has demonstrated its potential to distinguish chemically identical compounds coming from different sources. Despite the numerous applications of IRMS to a wide range of forensic materials, its implementation in a forensic framework is less straightforward than it appears. In addition, each laboratory has developed its own strategy of analysis on calibration, sequence design, standards utilisation and data treatment without a clear consensus. Through the experience acquired from research undertaken in different forensic fields, we propose a methodological framework of the whole process using IRMS methods. We emphasize the importance of considering isotopic results as part of a whole approach, when applying this technology to a particular forensic issue. The process is divided into six different steps, which should be considered for a thoughtful and relevant application. The dissection of this process into fundamental steps, further detailed, enables a better understanding of the essential, though not exhaustive, factors that have to be considered in order to obtain results of quality and sufficiently robust to proceed to retrospective analyses or interlaboratory comparisons.     

Are Preferences for Fiscal Discipline Endogenous

Differences in voters' fiscal preferencesare examined taking advantage of theexceptional Swiss institutional setting.Empirical evidence suggests thatpreferences are determined by strictlycultural patterns (cultural area measuredby language). Thus, fiscal preferences canbe considered as being largely exogenous.This implies that, except for specialcases, it is not possible to find simpleproxy variables for fiscal preferences. Anad hoc index of fiscal preferencesought to be built up when the introductionof this variable is required forcomprehensive explanatory models of fiscaldiscipline or for other related studies.     

L'ajustement mutuel dans le fonctionnement organique du système multiorganisationnel d'aide et de services aux sans‐abri de Montréal

Sommaire : Notre étude de l'organisation du secteur de l'aide et des services aux sans‐abri à Montréal Centre met en lumière un système multiorganisationnel de services de santé et de services sociaux qui n'est pas intégré hiérarchiquement dans son ensemble et qui n'est pas soumis à une « entente de gestion et d'imputabilité» globale propre à une gestion fondée sur la normalisation des résultats. L'étude présente un système d'ensemble de type « organique » plutôt que bureaucratique, largement fondé sur des ajustements mutuels entre les nombreux acteurs publics et « communautaires » de ce secteur. La coordination des services se réalise alors essentiellement dans les interactions entre les intervenants alors qu'ils accomplissent leur travail, et ce avec le soutien des gestionnaires. À l'aide de nombreux extraits d'entrevues, nous étudions le fonctionnement de ce système « organique » sous la forme de trois catégories de processus d'ajustement mutuel qui se superposent et se complètent pour assurer la valeur des services : disjoint unilatéral, conjoint bilatéral et conjoint multilatéral. Selon les sciences de l'organisation, un tel système est potentiellement mieux adaptéà composer avec la complexité des connaissances et des valeurs caractéristiques des services humains, qu'un à système formellement intégré et contrôlé par des règles, des indicateurs et des cibles quantifiables. Abstract: This study of the organization of the sector dedicated to providing aid and services to the homeless in Central Montreal reveals a multiorganizational health and social services system that is neither hierarchically integrated as a whole nor subject to a comprehensive “management and accountability agreement” specific to standardized results‐based management. The study details a comprehensive system that is “organic,” rather than bureaucratic, and broadly organized based on mutual adjustments among the numerous public and “community” practitioners in this sector. The coordination of services is therefore essentially achieved through the interaction of the workers as they perform their jobs, with the support of management. This study draws on a number of extracts from interviews to examine how this “organic” system operates, in the form of three distinct processes of mutual adjustment that are superimposed and complementary to ensure the value of the services: “unilateral disjoined,”“bilateral joined” and “multilateral joined.” According to organizational science, this type of system is potentially more likely to address the complexities inherent in the knowledge and values that are characteristic of human services than a formally integrated system that is controlled by rules, indicators and quantifiable targets.     

A power measure analysis of Amendment 36 in Colorado

Colorado’s Amendment 36 proposed to switch Colorado’s representation in the Electoral College from winner-takes-all to proportionality. We evaluate unilateral and uniform switches to proportionality both from Colorado’s perspective and from an impartial perspective on the basis of a priori and a posteriori voting power measures. The present system is to be preferred to a unilateral switch from any perspective on any measure. A uniform switch is to be preferred to the present system from Colorado’s perspective on an a priori measure, and from an impartial perspective on an a posteriori measure. The present system is to be preferred to a uniform switch from Colorado’s perspective on an a posteriori measure (with some qualifications), and from an impartial perspective on an a priori measure. We conclude with a discussion of the appropriateness of these measures.     

Politiques publiques et santé:les dilemmes de I‘évaluation prospective

Sommaire: Depuis le milieu des années 1990, plusieurs gouvernements ont affirmé leur volonté de tenir compte des impacts de leurs actions sur la santé des populations. En juin 2002, le gouvernement du Québec met en vigueur l'article 54 de la Loi sur la santé publique (L.R.Q. chapitre S‐22, 2001). Cet article atteste de l'obligation pour les ministères de tenir dorénavant compte des impacts sociaux, environnementaux et économiques de leurs actions sur la santé. La mise en Oeuvre de cet article suppose l'intégration d'un processus d'évaluation prospective des politiques publiques dans l'appareil gouvernemental, remet en question le fonctionnement vertical des administrations publiques et souligne l'importance d'une gestion stratégique des connaissances dans un monde sans frontières. Dans ce contexte, quatre dilemmes sont soulevés. Les deux premiers dilemmes sont d'ordre interministériel. Ils concernent les relations qu'entretiennent les ministéres entre eux et avec les organismes centraux. Les deux autres dilemmes s'intéressent à la dimension intra organisationnelle, c'est‐à‐dire la maniére dont chaque ministère réagit face aux demandes d'évaluations prospectives de ses politiques ou programmes et répond aux exigences dc l'article 54. Des méthodes qui devraient permettre aux administrations publiques de remédier à ces différents dilemmes sont également présentées. Abstract: Since the mid‐1990s, several governments have declared their commitment to ensuring that the impact of their actions on the health of the population is taken into account. In June 2002 the Quebec provincial government implemented article 54 of the Public Health Act (R.S.Q., chapter 2.2, 2001). This article stipulates the obligation on the part of the government departments to take into account the social, environmental, and economic impacts of their actions on public health in the future. The implementation of this article means integrating a process for the prospective assessment of the government's public policies, and re‐examining the vertical model of operation of public administrations; it also underlines the importance of strategic knowledge management in a world without borders. Four dilemmas are raised within this context. The first two dilemmas are interdepartmental in nature, and involve the relationships the government departments have with each other and with the central agencies. The other two dilemmas fall within the intra‐organizational sphere ‐ that is, the way in which each government department reacts to the demands for the prospective assessment of its public policies or programs, and how each department responds to the requirements of article 54. Processes that should allow the public administrations to solve these various dilemmas are also presented.     

A Structural Model of Autonomy in Middle and Late Adolescence: Connectedness,Separation, Detachment,and Agency

This study presents a comprehensive 4-factor model of autonomy in middle and late adolescence. Partially overlapping sets of scales on adolescent individuation and family functioning were correlated with each other in 2 independent studies. Data for the first study were taken from a sample of high school students in Grades 9–12 (N = 601), whereas the data for the second study were derived from a sample of 1st-year university students (N = 374). Confirmatory factor analysis on all of the scales and derivative subscales in both studies revealed a model that comprised 4 different but related factors, that is, Connectedness, Separation, Detachment, and Agency, all of which occupy a central place in different theories of adolescent autonomy. Connectedness and Detachment, and to a lesser extent Connectedness and Separation, were inversely related to one another. Correlations between Agency and the 3 other factors were much lower. Results are discussed with respect to the different views on autonomy that exist in the literature, and with respect to the term autonomy, which should be used as an umbrella term only. Implications for the conceptual basis of the Emotional Autonomy Scale are also outlined.     

Hair analysis of opiates in mothers and newborns for evaluating opiate exposure during pregnancy

The increasing interest in toxicological hair analysis as a marker of human exposure to xenobiotics such as illicit substances or therapeutic drugs, has been made feasible by the extension of mass spectrometry, a highly sensitive method of detection. A newborn exposed to drugs in utero can suffer from a varying degree of withdrawal syndrome, a few days after birth. If of opiate origin, the withdrawal syndrome can be treated with morphine, among other therapeutics, but it is not easy to diagnose because of atypical symptoms presented by neonates and especially when maternal drug addiction has not been revealed. To assess and measure toxicological factors linked with the appearance and the severity of this syndrome, maternal and neonatal matrices such as urine, meconium and hair were collected during a protocol approved by the ethical committee. Opiates in particular were measured with GC-MS and potential combined dependences (cannabis, cocaine, amphetamine, LSD and benzodiazepines) and/or substitutive therapeutics (methadone or buprenorphine) were also assessed in 17 mother/neonate couples. Gestational opiate exposure profiles were drawn up and linked with the observed withdrawal syndromes. A withdrawal syndrome seems to appear more frequently after foetal exposure to an association of opiates/substitutive molecules (8 out of 10 withdrawal syndromes observed in this study), although the impact of cocaine and benzodiazepines must also be taken into account. The results obtained in neonatal hair make it possible to affirm foetal drug exposure and are in accordance, for the majority, with the appearance of a neonatal withdrawal syndrome (NWS). Neonatal hair analysis could contribute to assess in utero exposure to opiates, particularly when results in urine and meconium are negative or when these matrices are not available.