人脑挫伤后细胞周期素D1表达的变化

目的研究CyclinD1在人不同部位脑挫伤组织中表达的变化及其与损伤时间的关系。方法88例脑挫伤标本按损伤后存活时间0.5,1,3,24h和3,7,14,30d分为8个实验组,另以6例非脑挫伤的脑作为对照组,应用CyclinD1免疫组织化学并结合图像分析技术观察CyclinD1的变化。结果脑挫伤后,挫伤灶中央CyclinD1阳性细胞几乎丧失,1h后挫伤灶周围CyclinD1阳性细胞开始增加,3h～30d之间各组挫伤灶周围免疫阳性反应的细胞增加显著,在3h～30d一直维持在较高水平;CyclinD1主要见于小胶质细胞和其它胶质细胞,少数神经元也呈阳性。结论人脑挫伤后,CyclinD1在多种脑细胞内表达,以胶质细胞表达明显,CyclinD1阳性细胞在伤后不久即显著增加,故可作为早期脑损伤的诊断指标。     

Heat stroke deaths caused by electric blankets: case report and review of the literature

Heat stroke is the most serious and potentially life-threatening condition of the heat-related illnesses. Heat stroke deaths caused by electric blanket are rarely reported. In this paper, we report 2 cases of fatal heat stroke caused by overheating from electric blankets in winter. One was a 41-year-old man who was found unresponsive in bed on an electric blanket. His wife shared the same bed with him and was found unconscious. The wife's axillary temperature was 40 degrees C (104 degrees C) when she was admitted to the hospital. She fully recovered after medical treatment. The husband was pronounced dead at scene, with rectal temperature at 41.2 degrees C (106.2 degrees C). The other was a 13-year-old girl who was found dead in bed on an electric blanket, with rectal temperature at 41 degrees C (105.8 degrees F). The literature is reviewed, and the pertinent findings, including scene investigations, postmortem examination, the risk and mechanism of fatal heat stroke caused by using electric blanket, are discussed.     

法院人事制度改革中对资深法官的保护

学问渊博、经验丰富的资深法官是不可多得的司法财富 ,我国应从人事制度上给予他们特殊的对待和保护。     

融会古今 兼采中外——瞿葆奎先生教育思想纪略

瞿葆奎先生以"融会古今,兼采中外"为治学的追求,为中国教育基本理论的发展做出了多方面的贡献.其中,有对教育学学科的建设性探索;有对马克思教育概念和思想的辨译和阐释;有对课程与教学理论问题的挖掘;也有对教育研究的方法论反思.此外,他不仅关注教育学基本资料的建设和积累,强调教育实践之于教育理论的重要意义,重视教育理论之于教育实践的服务功能与教育理论审视教育实践的本质使命,而且还积极参与教育学术规范的建立.     

Induction of hypoxia-inducible factor-1alpha in two kinds of rats asphyxiation death models

OBJECTIVE: To investigate the expression of hypoxia-inducible factor 1-alpha (HIF1-alpha) in the heart, lung, liver and kidney in rats died of two typical models of asphyxia. METHODS: Two asphyxia models were made and tissue samples of the dead rats were collected from different groups at various postmortem duration. The expression and the changes of HIF1-alpha in various tissues were examined by immunohistochemistry and image analysis techniques. Results Significant expression of HIF1-alpha was observed in the myocardial fibers, kidney cells, liver cells and lung cells in both asphyxia models, but not in the control group. The expression of HIF1-alpha in various tissues in the rat died of nitrogen gas breathing was found in the nuclei at 0 hour and the expression level decreased gradually thereafter. The HIF1-alpha expression level and duration in various tissues of the rat died of hanging were higher and longer than that of the former group, with a peak of the expression level observed 6 hours after death, and then started to decline in all tissues except the heart where the expression still showed an increase 24 hours after death. The control groups showed a steady expression in the cytoplasm but not in the nuclei. CONCLUSION: HIF1-alpha appears to be a valuable biomarker in the diagnosis of asphyxia within 24 hours after death.     

中国船员涉外人身伤亡救济模式研究

近年来多发的船员涉外人身伤亡案件体现了船员权益保护问题的紧迫性。船员涉外人身伤亡主要分为地点涉外和主体涉外两种,均可以船员国籍和船舶国籍为连接点适用中国法。目前我国调整船员劳动和劳务关系的条文散见于多部法律法规和司法解释,本文以最新船员法规、劳动法规、社会保险法规和2006海事劳工公约为依据,清理诸法头绪,结合海员外派制度,分析得出中国船员涉外人身伤亡主要有工伤保险、保赔保险、商业保险及损害赔偿诉讼四种救济模式,并详细研究各种模式的利弊。     

生活方式市民化——对农转非居民消费模式与闲暇模式的探讨

在中国当下环境中,城市化是不可阻挡的潮流,这必将带来人口的市民化过程。除了包括制度身份的改变,市民化还包括适应城市一整套的生活方式。本文的研究对象是已经完成制度层面市民化的人,即已经获得城市户口的农民,试图讨论他们在消费方式、闲暇方式等生活方式方面的市民化程度。本文假设,即使完成了身份、居住地的转变,农民的市民化仍然是个漫长的过程,户籍的转变并不能直接带来生活方式的转变。     

野田内阁加入TPP的战略意图探析

TPP是一种旨在实现贸易、投资及人员往来等全面自由化的高水平自由贸易协定。野田内阁意图通过TPP提升日本企业的国际竞争力,推动国内农业的结构性改革,重振日本经济;在对外关系上,则欲借此修复巩固日美同盟,配合美国牵制中国的战略布局,并在未来亚太经济一体化的进程中占据有利位置。基于上述战略意图,尽管遭到日本国内长期依赖财政补贴及贸易保护的农业部门和希望继续维持现有医疗保障体系的医师会等团体的坚决反对,以致日本面临政治分裂的风险,野田仍作出了参加TPP谈判的政治决断。     

东南亚国家的经济外交与地区安全秩序的重塑

冷战结束后,塑造东亚地区安全秩序的力量来源主要有两个:一是雅尔塔体系的遗产,二是东南亚国家的经济外交。一方面,中国与俄罗斯通过上海合作组织构建了在安全等领域的合作,而美国在美日同盟的基础上强化了其在东亚的单边及多边同盟体系。因此,雅尔塔体系遗产的组织化程度较以往明显提高。另一方面,东南亚诸国通过在东盟"10+"合作框架、亚太经合组织以及亚欧会议等平台实施经济外交,比较成功地把主要大国及区域集团力量牵绊在东亚地区,并藉此影响了冷战后东亚地区的政治、安全秩序。