Comprehensive analyses for genetic diversities of 19 autosomal STRs in Chinese Kazak group and its phylogenetic relationships with other continental populations

Short tandem repeats (STRs) play an essential role in forensic genetics due to their high degree of polymorphisms, wide distributions and easy detection method. In this study, allelic frequencies and forensic statistical parameters of the 19 autosomal STR loci in a Kazak ethnic group were calculated, and its genetic relationships with reference populations were assessed in order to understand population structure better and enrich population genetic data for forensic practice in Chinese Kazak ethnic group. There were 226 identified alleles with the corresponding allelic frequencies ranging from 0.0008 to 0.5295 in the 628 unrelated healthy Kazak individuals in Xinjiang Uygur Autonomous Region. All autosomal STRs were conformed to the Hardy-Weinberg equilibrium after Bonferroni’s correction. The cumulative power of discrimination and the combined probability of exclusion of all the 19 autosomal STRs were 0.999 999 999 999 999 999 999 997 162 and 0.999 999 994 484, respectively. Furthermore, the D_A distances and Fixation index values of pairwise populations, principal component analysis, multidimensional scaling analysis, phylogenetic tree analysis and structure analysis were conducted to probe the genetic relationships between the Kazak group and other reference populations. The population genetic results showed that these 19 autosomal STR loci were characterised by high genetic diversities in the Kazak group. Furthermore, the studied Kazak group had close genetic relationships with the Uyghur group and the Uzbek group. The present results may facilitate understanding the genetic background of the Chinese Xinjiang Kazak group.     

大数据技术运用嵌入“智慧党建”的底层逻辑与发展图景北大核心SSCI

《中共中央关于加强党的政治建设的意见》明确提出了运用大数据等新兴技术推进“智慧党建”的要求。虽然相关实践活动得以积极开展,但目前对于大数据技术运用嵌入“智慧党建”的底层逻辑和发展图景还缺乏更清晰的认识。“智慧党建”的规定性要求与主要趋向应集中体现于蓄力智能创新、强化党的领导、加强政治建设、运用新兴技术及建设系统体系诸方面。相关底层逻辑应聚焦于增强“智慧党建”的感知化、互联化、智能化、科学性及安全性等方面。相关发展图景应围绕着在“智慧党建”中不断强化政治统领作用、推动党员坚定理想信念、提升组织活动的质与效、增进与群众的血肉联系、加强执纪守法管控力度、促动优良制度生成优化及实现监督监控工作创新等层面而展开。     

National Identity of Locality: The State,Patriotism, and Nationalism in Cyber China

Journal of Chinese Political Science - National identity is the cognition of citizens regarding to which political community they belong, and the tendency to accept the political, cultural and...     

我国新型职业农民培育的政策目标与实践探索

培育新型职业农民是促进我国农业供给侧结构性改革的关键,是破解“谁来种地,谁会种地”这一突出社会问题的重要路径。目前,我国培育新型职业农民还处于探索时期,缺乏成熟的经验,新型职业农民培育实践与新型职业农民培育的政策导向和发展目标具有较大的偏差。数据显示,新型职业农民培育实践存在以下问题:选择培育对象缺乏针对性;培育方式不合理;管理部门较多,资源分散;监督机制不健全等。在农民层面,主要存在思想认识不清,参与动力不足;受教育程度普遍较低,知识水平与接受能力有限等问题。研究表明,精准定位培育对象并实行差异化分类培训;及时获取培育反馈,建立科学规范的培育机制;建立新型职业农民培育综合管理部门;改进考核评价体系,提高农民参与培育的积极性;建立农业准入机制,明确农民职业身份概念;加强农村基础教育、职业教育,开发“一主多元”的新型职业农民培训体系等改进策略对提高新型职业农民培育实践效果具有显著作用。     

体面劳动与劳动文化学的构建

体面劳动其理论性质属劳动文化范畴.体面劳动的提出凸显了加强劳动文化研究的紧迫性.劳动文化学研究必须以大多数劳动者的劳动观念和诉求为根基.劳动文化学主要内容有劳动神圣、劳动和谐、劳动规范、劳动道德、劳动模范、劳动文明等.     

针刺合独参注射液对实验性家兔急性心衰竭心肌力学参数影响

目的 :探讨针药结合治疗急性心衰竭的疗效。方法 :4 8只日本大耳白兔 ,随机分为 4组 ,分别为正常组、模型组、治疗组和对照组。静脉注射戊巴比妥钠复制急性心衰竭模型。观察针刺配合中药治疗后其心肌力学参数的变化。结果 :治疗组有明显改善急性心衰竭的作用 ,与对照组比较无差异显著 (P >0 .0 5) ;但治疗组药效维持时间长 ,与对照组有显著差异 (P <0 .0 5)。结论 :针药结合治疗心衰竭值得临床推广应用。