How Serious is the Global Warming Threat?

Despite the media’s and politicians’ insistence that the science of global warming is “settled”, there are good reasons to distrust climate model projections of future global warming. While the supposed scientific consensus is that mankind is very likely to blame for recent global warmth, this is mostly a statement of faith made from a position of relative ignorance about natural variability in the climate system. Since we do not understand what causes decadal- to century-scale natural climate variability, it has simply been assumed to either not exist, or to be relatively small. But even if predictions of catastrophic warming are accurate, the worldwide demand for energy is so large that there is little mankind can do without radically new energy technologies. Since it is only the wealthy countries of the world that can afford the R&D efforts to develop those technologies, punishing the use of fossil fuels, and the resulting negative impact on economies, might well delay the development of cost effective carbon-free energy sources that so many people are now calling for.

An original cause of drowning in an industrial environment

We describe an original case of drowning in a wax tank in an industrial setting. The causes of death were multiple, with the association of drowning, mechanical asphyxia, and extensive superficial burns. To our knowledge, it is the first report of drowning in wax, and only 7 previous related observations of drowning in industrial environments were reported in the international literature. These accidents are more often fatal, with multiple associated causes of death due to the incriminated media. Although exceptional, these serious accidents must be prevented in potentially risky industries.     

Simultaneous analysis of six amphetamines and analogues in hair, blood and urine by LC-ESI-MS/MS. Application to the determination of MDMA after low ecstasy intake

A rapid and sensitive method using LC-MS/MS triple stage quadrupole for the determination of traces of amphetamine (AP), methamphetamine (MA), 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"), 3,4-methylenedioxyethamphetamine (MDEA), and N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB) in hair, blood and urine has been developed and validated. Chromatography was carried out on an Uptisphere ODB C(18) 5 microm, 2.1 mm x 150 mm column (Interchim, France) with a gradient of acetonitrile and formate 2 mM pH 3.0 buffer. Urine and blood were extracted with Toxitube A (Varian, France). Segmented scalp hair was treated by incubation 15 min at 80 degrees C in NaOH 1M before liquid-liquid extraction with hexane/ethyl acetate (2/1, v/v). The limits of quantification (LOQ) in blood and urine were at 0.1 ng/mL for all analytes. In hair, LOQ was <5 pg/mg for MA, MDMA, MDEA and MBDB, at 14.7 pg/mg for AP and 15.7 pg/mg for MDA. Calibration curves were linear in the range 0.1-50 ng/mL in blood and urine; in the range 5-500 pg/mg for MA, MDMA, MDEA and MBDB, and 20-500 pg/mg for AP and MDA. Inter-day precisions were <13% for all analytes in all matrices. Accuracy was <20% in blood and urine at 1 and 50 ng/mL and <10% in hair at 20 and 250 pg/mg. This method was applied to the determination of MDMA in a forensic case of single administration of ecstasy to a 16-year-old female without her knowledge during a party. She suffered from hyperactivity, sweating and agitation. A first sample of urine was collected a few hours after (T+12h) and tested positive to amphetamines by immunoassay by a clinical laboratory. Blood and urine were sampled for forensic purposes at day 8 (D+8) and scalp hair at day 60 (D+60). No MDMA was detected in blood, but urine and hair were tested positive, respectively at 0.42 ng/mL and at 22 pg/mg in hair only in the segment corresponding to the period of the offence, while no MDA was detectable. This method allows the detection of MDMA up to 8 days in urine after single intake.     

Usefulness of Systematic Histological Examination in Routine Forensic Autopsy*

Abstract: The forensic community does not agree on the need to perform histological examination at forensic autopsy. The aim of our study was to determine the usefulness of systematic standard histology in forensic autopsies. A prospective study was carried out on 428 autopsy cases for which standard histological examination was systematic. Mechanism of death not shown by gross anatomic findings was discovered by histology in about 40% of the cases. Cause of death was established by only histology in 8.4% of the cases. Microscopic findings affected the manner of death in 13% of the cases. Histology provided complementary information about prior medical condition of the deceased in about 49% of the cases. Traumatic lesions were better documented by histology in about 22% of the cases. According to the results of our study, systematic standard histology for the main organs should be used in routine forensic autopsies.     

Contours of the Naga Upsurge

The Naga upsurge is the manifestation of one of the earliest ethnic unrests in North East India. The Nagas claim that they have been living in their present quarters since ancient times and that they have never been conquered by any foreign force. In their view their fight cannot be considered to be secessionist and is rather a freedom movement. But there are others who view that the Naga nation formation is rather a post British phenomenon. Nagas are a very heterogenous group with various linguistic affiliations. But they have been able to carve out a niche and many new tribes are being drawn to the Naga constellation. The Naga drive may be correct, but their rationale needs to be viewed from the process of formation of the Indian nation–state and its democratic foundation which is rather skewed. In a just confederation of states, the Nagas can hope to attain an equal share as any other nationality. But it needs to be realized that the Indian nation–state cannot be looked upon in a frozen time frame as political boundaries are bound to alter with changing aspirations of the people, in line with the shifts in politico–economic equations globally and regionally.