超高效液相色谱-质谱法测定人全血中甲胺磷、乙酰甲胺磷含量

目的应用超高效液相色谱-质谱法(UPLC-MS/MS)对人全血中甲胺磷、乙酰甲胺磷进行定量测定。方法采用去离子水直接稀释人全血,提取血中的甲胺磷及乙酰甲胺磷,以甲醇-水(含0.1%甲酸)为流动相梯度洗脱,正离子化多反应监测(MRM)模式测定。结果甲胺磷、乙酰甲胺磷的回收率均高于87%。在选定条件下全血中甲胺磷、乙酰甲胺磷的线性范围为2～200ng/ml,最小定量限为2ng/ml。结论将全血样品进行直接稀释并应用液相色谱-质谱法进行检测可作为甲胺磷及乙酰甲胺磷中毒的快速检测方法。     

一起医疗纠纷引发的民事诉讼和行政复议案的思考

以一起医疗损害赔偿纠纷案件引发的民事诉讼和行政复议为例,分析了案例中的几个焦点问题,包括卫生行政部门是否有权审核民事诉讼中的鉴定行为及鉴定结论、是否可以根据民事审判结果做出行政处罚等。强调卫生行政部门应当注意民事诉讼和行政复议的关系,避免出现行政干预司法的违法行政后果,并在此基础上总结了几点办案体会。     

中国财政部救助问题银行法律制度的完善——以美国为鉴

财政部救助问题银行是避免问题银行破产的最后一道屏障。多年来,美国财政部救助问题银行逐渐形成了＂保护纳税人权益＂、＂成本可回收＂、＂最后手段性＂三项基本法律原则,并被严格恪守。相比之下,中国财政部救助问题银行的立法与实践匮乏,相关法律原则阙如,与救助相关的部分财政法律制度亟待调整。     

How do offenders move through the stages of change?

This study sought to investigate the way in which offenders moved through the stages of change. The University of Rhode Island Change Assessment Scale (URICA) was administered to a group of general offenders (N = 371) who participated in the Short Motivational Programme (SMP), a brief motivational interviewing programme administered to medium-risk offenders in New Zealand. The offenders' URICA responses were subjected to a cross-lagged panel analysis using structural equation modelling. Four models specifying different prospective associations between stage engagements were examined. It was hypothesised that there would be support for sequential transitions through the stages as proposed by the Stages of Change model. However, the analysis rendered support for and against sequential transitions, in that offenders regressed to earlier stages or skipped a stage post-SMP. Offenders who skipped to an adjacent stage after the SMP may have actually passed through an intermediary stage during the intervention, and those who regressed to an earlier stage post-SMP may have gained a more realistic awareness of their problem behaviour. This finding also raises questions about the practical utility of the model with offenders and highlights the need for more rigorous studies investigating the way offenders move through the stages of change.     

Public policy and quality of community life in american cities: a search for linkage

The purpose of this research is to identify and examine linkages that exist between public policy and quality of life in American cities. A review and analysis of public policy research and social indicators research over the past twenty years is included. Social indicators are further defined into both objective and subjective indicators. The developing confluence of the two areas of research constitutes the basis for the remainder of the paper.

The data for this study are derived from a nationwide survey conducted by Louis Harris and Associates, Inc., in late December, 1977 and early January, 1978, for the U.S. Department of Housing and Urban Development (HUD). Interviews were conducted for a sample of 7,074 adults, asking them about their perceptions on the quality of community life, government services, social problems, and future possibilities. The findings are analyzed through use of a frequency distribution of the quality of life measures and the quality of public service variables.

The pattern of statistical relationships indicates that the nine public service variables are sharply divided into two groups. One, seven variables (police, garbage, street lighting, fire, public schools, parks and playgrounds, and road and street maintenance) are all highly inter-correlated. The correlation coefficients among them range from a high of .411 (police and fire) to a low of .218 (garbage and public schools). The other, public transportation and public health service are also closely inter-correlated, but their relationships with the other seven are all uniformly weak.

These two groups of public services have distinct political and policy implications. The first group of services tends to represent those traditionally well-established public services that are considered “vitally important” for the well-being of the general public. The second group, in contrast, tends to represent those public services that are relatively new and serving primarily the needs of low income or minority groups in the community whose political influence is most likely to be marginal.

A few generalizations may be drawn from the statistical relationships. First, the general indicators of community life quality such as feelings about the overall community and neighborhood are more strongly correlated with the quality ratings of public services than the quality indicators of specific life domains. Second, some of the strongest relationships are found between specific public services and specific domains of life quality that might be expected logically to have close association such as police and safety (r=.317) and public schools and child raising (r=.427). Third, those public services that are considered part of mainstream local services and important for the daily life of the general public (such as police, fire, public schools, parks and playgrounds, etc.) tend to be very strongly correlated with the measures of community life quality. Fourth, in contrast, those services that are primarily affecting underprivileged groups in the community and not considered part of the mainstream of local services are poorly or insignificantly correlated with the measures of community life quality.     

双语语言转换代价理论研究

语言转换代价是认知心理学研究的热点和焦点问题。以特定语言选择模型和非特定语言选择模型为出发点,阐述心理学家在行为研究、脑的电生理技术、脑成像技术和脑的病理研究方面所取得的进展,对研究成果进行评价,指出探索双语者语言转换奥秘是一个复杂的过程,需要在进一步提高研究方法的信度和效度上下功夫。     

PBL教学模式下《操作系统》课程教学改革

研究PBL教学方法,对于操作系统这样一门理论理解和实践应用并重的课程运用以问题为导向的教学方法,将学习与任务或问题挂钩,强调把学习设置到特定的、有意义的问题情景中,通过学习者的自主探究和协同合作来解决问题,从而学习隐含在问题背后的学科知识,形成自主学习的能力和解决问题的技能。     

影响西部少数民族地区政治稳定的五大认同机制

对西部少数民族地区政治稳定起决定性作用的是民族、政治、经济、宗教和风俗习惯等五大认同机制。其中,民族认同机制是基石,它奠定了西部少数民族地区政治稳定的血缘基础;政治认同机制是核心,它奠定了西部少数民族地区政治稳定的制度基础;经济认同机制是关键,它奠定了西部少数民族地区政治稳定的利益基础;宗教与民族风俗习惯认同机制是两大重要组成部分,前者奠定了西部少数民族地区政治稳定的价值基础,而后者则是西部少数民族地区政治稳定的重要润滑剂。