Simultaneous Quantitative Determination of Amphetamines,Opiates, Ketamine,Cocaine and Metabolites in Human Hair: Application to Forensic Cases of Drug Abuse

A method using liquid chromatography–tandem mass spectrometry (LC–MS/MS) to simultaneously quantify amphetamines, opiates, ketamine, cocaine, and metabolites in human hair is described. Hair samples (50 mg) were extracted with methanol utilizing cryogenic grinding. Calibration curves for all the analytes were established in the concentration range 0.05–10 ng/mg. The recoveries were above 72%, except for AMP at the limit of quantification (LOQ), which was 48%. The accuracies were within ±20% at the LOQ (0.05 ng/mg) and between −11% and 13.3% at 0.3 and 9.5 ng/mg, respectively. The intraday and interday precisions were within 19.6% and 19.8%, respectively. A proficiency test was applied to the validated method with z-scores within ±2, demonstrating the accuracy of the method for the determination of drugs of abuse in the hair of individuals suspected of abusing drugs. The hair concentration ranges, means, and medians are summarized for abused drugs in 158 authentic cases.     

溺死相关浮游生物基因座的复合扩增体系

目的构建溺死相关浮游生物基因座的复合扩增体系,验证体系特异性并评估其在法医溺死诊断中的应用价值。方法针对溺死相关浮游生物同源基因序列,设计特异性引物,并用FAM、HEX、TAMRA、ROX、SIZ荧光染料分组标记,构建复合扩增体系;进行体系特异性验证;以16例实验猪样本评估体系检验效能;复合扩增体系、硅藻形态学MD-VF-Auto SEM检测法及硅藻rbc L基因PCR-CE检测法分别检测28例案件样本,比较分析应用效果。结果该复合扩增体系共包含14个基因座,可特异性扩增35种浮游藻类和3种浮游细菌,人、3种人体共生菌及8种浮游细菌均为阴性。以该体系检测溺死实验猪,阳性率为90%,非溺死实验猪均未检出;检测溺死案件样本,阳性率为96%,非溺死案件均未检出。复合扩增体系与MD-VF-Auto SEM法检测案件尸体肺、肝和肾的阳性率均不具有统计学差异(P>0.05),但其与硅藻rbcL基因PCR-CE法检测案件肝和肾的阳性率均具有统计学差异(P<0.05)。结论本文针对多种溺死相关浮游生物14个基因建立的复合扩增体系,具备多种靶物种的特异性遗传标记,且所需检材量小,提高了检测效能,在法医溺死鉴定中具有良好的应用前景。     

现货与期货交易的界分标准与法律规制

商品现货中远期交易平台具有促进商品交换与商品流通、管理风险等多种功能,在服务实体经济中具有特殊地位。从历史上看,是先有现货中远期交易,而后才演化出了期货交易,二者关联度极高。区分现货与期货交易,应从二者不同的交易目的、功能定位、主体特征和交易结果等整体情况综合判定,而不宜倚重于依据二者某些交易规则的相似性进行显性判断。其相关立法、行政监管和司法裁判应坚持整体判断标准,进一步促进此类平台向服务实体经济转型。     

论我国传染病疫情防控法律原则之完善

2003年春季,全球暴发流行严重急性呼吸综合征(以下简称SARS)。中国在抗击SARS之后,修订了《传染病防治法》,并制定了《突发公共卫生事件应急条例》。这标志着中国政府的应急管理模式从行政管理模式向法治模式的转变。然而,2020年年交之际的新型冠状病毒肺炎(以下简称新冠肺炎)疫情防控中,仍然暴露出了诸多法律问题。习近平在中央全面深化改革委员会第十二次会议上强调,要认真评估传染病防治法等法律法规的修改完善。本文试图从疫情防控中的具体现实问题入手,归纳出《传染病防治法》已有法律原则之外,还应当遵循的其他法律原则,以期为日后修法和法律适用有所帮助。     

US-China Trade War: Is Winter Coming for Global Trade?

Journal of Chinese Political Science - This paper uses the SMART Model to analyze the direct economic effects of the US-China tariff war on both China and the US. Based on the three lists of...     

Effects of Work Boundary Strength on Employees' Emotional Exhaustion:The Mediating Role of Role Stress

Based on organizational support theory and “stressor-strain-outcome” model, this study constructs a moderated mediation model to research the mechanism between workload boundary and employees’ emotional exhaustion. Using a questionnaire survey, the results show that there is a U-shape relationship between the workload boundary and the employees’ emotional exhaustion; and this relationship is mediated by employees’ role stress. Furthermore, boundary flexibility moderates the U-shape relationship between workload boundary and employees’ role stress. This means that the boundary flexibility can help reduce the negative effects of the workload boundary on the employees’ role stress, and compared with too strong and too weak workload boundary, the reduced negative effects are the most appropriate when the workload boundary is in the middle. Lastly, workload flexibility moderates the mediation effects of employees’ role stress.     

国际法视野下的官方出口信贷——由WTO专家组裁决透视《补贴与反补贴协定》附件1第(k)项规定

为了鼓励和支持本国对外贸易的发展,各国一般都会设立国家政策性银行,以提供官方出口信贷的方式来提供信贷和融资支持,以解决企业发展资金难的问题,特别是在飞机、船舶等设备进出口领域,更是如此。我国也不例外,专门设立了中国进出口银行来鼓励和支持设备进出口的发展。然而,官方出口信贷在WTO国际法体制下是否是允许的呢?这一问题构成各国政策选择的先决性问题。本文即主要着眼于对这一问题的分析,希望能对我国官方出口信贷,特别是船舶领域官方出口信贷支持的发展提供理论借鉴。     

对影响民警警察权与人权意识的相关因素的探讨

民警警察权与人权意识的形成,不仅依赖于这一职业群体对警察权与人权的知识和基本原理的认识程度、对警察权功能的认识、对人权状况的评价、对于基本权利保护和行使状况的感受等,正确意识的形成还深受来自生活环境、职业环境、职业素质等多种相关因素的深刻影响,对这些相关因素的分析,将有助于进一步探讨民警这一职业群体正确的警察权与人权意识培养的途径。     

论沈从文的苗族文化心理

湘西独特的人文环境,孕育了沈从文浓厚的苗族文化心理。这种文化心理,赋予了作家认识世界的独特目光和审美情趣,孕育了他的个性,影响了他一生的处事态度。这种心理主导下的创作思想,在一个以汉儒文化和西方文明为主流的都市文化背景下,不失为一种特立独行的创作个性。     

中美现行遗嘱继承制度比较研究

与美国现行遗嘱继承制度相比较，我国遗嘱继承制度存在诸多问题，完善我国遗嘱继承制度显得非常必要。