人参注射液治疗冠心病心气虚证与心阴虚证的临床研究

We have researched clinical effect of treated 57 cases of heart-Qi deficiency and heart-Yin deficiency of coronary heart disease with Ginseng injections. The results indicate Ginseng can improve angina pectorss and electrocardiogram,hemorrheogical indices,external thrombogenesis,microcirculation s'' abnormality; degrease symptom indices of heart-Qi deficiency of coronary heart disease remarkablely. But Ginseng have worse effect of angina pectoris and electrocardiogram to heart-Yin deficiency than to heart-Qi;deficiency of coronary heart disease; and symptom indices. hemorrheogical indices, external thrombogenesis, microcirculation in heart-Yin deficiency worsen. These prove there must be syndrome-differentiation in treatment of coronary heart disease with Ginseng injections.     

肝豆状核变性肝脏声像图特征的再探讨

１４０例肝豆状核变性的肝脏声像图特征分为７型；脂肪均匀浸润型，脂肪非均匀多灶浸润型，脂肪非均匀弥漫浸润型，光点光烁型，岩层征型，树枝状光带型和结节型。ＨＬＤ多样面肌痉挛是复杂的肝脏声像图特征与詹病程发展的不同阶段有关，反映肝 铜沉积由轻到重的病理过程，有助于对ＨＬＤ的诊断和病情分析。     

Sudden Death Due to Undiagnosed Rheumatic Heart Disease in a Child

We report the case of a 5‐year‐old boy who died from complications of rheumatic heart disease with atypical presentation. He was hospitalized for recent inflammatory and neurological symptoms. He was diagnosed with viral encephalitis. He died the day after he was discharged. The macroscopic autopsy findings were unremarkable. Histology revealed typical rheumatic heart disease. Neuropathology showed cerebral infarction due to an embolic event linked with the rheumatic valvulitis. The cause of death was determined as heart failure due to rheumatic heart disease secondary to an undiagnosed acute rheumatic fever. It is related to an autoimmune response to infection with group A streptococcus. It mainly affects children in developing countries. In our case, viral encephalitis was consistent with the medical history and the proper diagnosis was made on histological analysis. Forensic pathologists should consider this diagnosis facing a sudden unexpected death in childhood, even in industrialized countries.     

口蹄疫病毒3D蛋白对DNA疫苗免疫效果的影响

将携带O型FMDVChina 99株P1 2A、部分 2B及 3C蛋白酶编码基因的真核表达质粒与在毕赤酵母中表达的纯化FMDVChina 99株 3D蛋白同时经肌肉注射方法接种豚鼠。以MTT法检测豚鼠脾淋巴细胞经植物血凝素 (PHA)刺激后的增殖活性 ,以间接ELISA方法检测血清FMDV特异抗体变化 ,并以微量中和试验检测中和抗体水平。结果表明 ,FMDDNA疫苗与 3D蛋白共同免疫豚鼠后 ,抗体水平没有明显提高 ,攻毒后的保护率为 2 5 %。     

锦鲤疱疹病毒病的研究进展

概述了锦鲤疱疹病毒病的流行状况、临床症状和病理特征,阐述了锦鲤疱疹病毒的基因组特征,以及在分离培养、流行病学、检测方法和疫苗研究方面取得的进展,旨在为深入研究该病提供理论参考。     

卫生知识与性别分工——近代中国传染病知识的性别化传播研究

女性是近代传染病知识传播的重要受众。得益于近代中国对传染病防治的日益重视和家庭在传染病防治中的特殊地位,妇女报刊和以教科书为基础的学校教育将较为系统前沿的传染病知识传播给女性。同时,通俗实用的传染病知识也经由民众教育向普通城乡妇女传播。在近代传染病知识向女性传播的过程中,性别化传播始终存在。传统性别分工成为向女性传播传染病知识的重要依据,性别化传播也在一定程度上强化了传统性别分工。但在缺乏医学启蒙的近代中国,围绕家庭的知识传播,向女性提供了必要的传染病防治知识。近代中国重视以家庭为单位的传染病知识传播策略,可以给当下提升城乡居民传染病防治素养以启示。     

口蹄疫A型灭活疫苗毒种和种子批的研究

为了保证制苗及攻毒用毒种的质量和稳定性,在对制苗和攻毒毒种的毒力、特异性、保存期、扩繁代次等进行研究的基础上,建立了口蹄疫A型灭活疫苗制苗和攻毒用毒种种子批。结果表明,原始毒种和基础毒种的扩繁代次均控制在5代以内,适宜的保存方法和保存期均为加含 500 mL／L甘油的PBS后在-30℃保存1年、-70℃保存2年;用于生产抗原的工作毒种,最高扩繁代次控制在15代以内,最佳保存方法和保存期为加保护剂后在-20℃保存半年、-70℃保存1 年;用于效力检验的攻毒毒种采用原始毒种。通过制苗和攻毒用毒种种子批的建立,规范了口蹄疫疫苗生产和检验过程中的毒种管理。     

论精神分裂症与外力致伤的关系：从一例司法精神鉴定案的始末谈起

司法精神鉴定具有特定的复杂性,尤其是对于外力致伤程度的评定应严格把握好外伤所致精神病与外伤所诱发的精神病的鉴定标准。     

口蹄疫病毒3C蛋白酶的T4噬菌体表面展示

对FMDV 3C基因克隆质粒p3C-T进行PCR扩增,获得了口蹄疫病毒3C蛋白酶基因片段,将此片段与T4噬菌体整合质粒pR的EcoRⅠ酶切片段连接,转化E．coli,DH5α工程菌,经EcoRⅠ酶切、质粒PCR扩增、插入方向筛选及测序鉴定,成功获得了T4噬菌体重组整合质粒pR- 3C。将其转化E．coli E2后,与SOC基因缺失的噬菌体φT4-Z1同源重组,经溶菌酶依赖性筛选,获得了快速溶菌型噬菌体φT4-3C。经噬菌体PCR扩增、SDS-PAGE分析和Western-bot分析,重组噬菌体可展示约26 ku的重组蛋白;其大小与预期相符,具有免疫原性。     

Cancer,HIV, and terrorism: translating public health models for prevention and control to counter-terrorism

What can cancer and HIV tell us about terrorism? How would we proceed if terrorism were a disease? A comparison of cancer and HIV can suggest alternative ways of conceptualizing terrorism and counter-terrorism using contrasting disease models that emphasize differing connections between etiology and prevention and control. A public health model also can help us think about terrorism as a basic research problem to be translated into therapeutic and preventive applications rather than primarily as a policy or political problem that makes only selective use of research studies. Through this re-conceptualization of terrorism as a basic and translational research challenge, we can draw upon the examples of the U.S. ‘War on Cancer’ and response to the ‘Aids Epidemic’ to help identify gaps in organizing academic and other resources to wage the ‘War on Terrorism.’ Recognizing and addressing these gaps could ultimately pave the way for more effective strategies in understanding and responding to the significant threats posed by terrorism, from the identification of factors that produce terrorist acts to the implementation of informed measures for the prevention and control of terrorist, and even proto-terrorist, activity.