The use of Hemastix® severely reduces DNA recovery using the BioRobot® EZ1

Abstract: The choice of reagents for presumptive tests for blood, and subsequent extraction methodologies, can significantly affect both the quantity and quality of purified DNA. Blood samples directly tested with Hemastix^® yielded <1% of the DNA recovered from untested samples when purified using the Qiagen BioRobot^® EZ1 and EZ1^® DNA Investigator kit. Full short tandem repeat profiles were obtained from both tested and untested samples, suggesting that the Hemastix^® reagent(s) affect DNA binding, rather than produce DNA damage. The Hemastix^® inhibition of DNA yield could be overcome by the addition of MTL buffer to the sample prior to extraction. Laboratories may wish to modify current procedures for extracting blood samples, utilize other extraction/purification methodologies, or inform their submitting agencies to avoid direct exposure of questioned bloodstains to Hemastix^® reagents.     

人类D19S40基因座在不同人种中的遗传多态性研究

采用ＰＣＲ技术分析中国汉族、德国人、斯洛伐克人和美国黑人群体Ｄ１９Ｓ４００基因座的遗传多态性及世界三大人种之间的差异。四个群体共调查了６２０人,发现了１１个等位基因,观察到４７种基因型。各群体观察杂合度为：０．７８～０．８８,个人识别机率为：０．９３８５０～０．９６６４。四个群体基因型频率分布符合Ｈａｒｄｙ－Ｗｅｉｎｂｅｒｇ平衡（Ｐ＞０．０５）,三大人种（蒙古人种、高加索人种、美国黑人）之间Ｄ１９Ｓ４００基因座等位基因频率分布存在极显著差异（Ｐ＜０．０１）。结果显示Ｄ１９Ｓ４００基因座在群体遗传学研究和法医学个人识别中有较高应用价值     

Global economic resilience: Analyzing the diverse impacts of the COVID-19 pandemic on the US,Pakistan, and the world

The economic development of a state can be accurately characterized as the measurable changes in macroeconomic indicators that result in an increase in the overall production or output over a specific timeframe, in comparison to the previous period. Several key macroeconomic factors contribute to the advancement of economic growth. These factors include the industrial production, unemployment rate, business Confidence Index, government budget deficit, and the labor force participation rate. The study employed secondary data from January 2016 to August 2023, with a monthly frequency, to estimate the coefficients. The data encompassed the United States, Pakistan, and the rest of the world. The empirical findings indicate that there exists a negative relationship between equality and economic growth in the United States, Pakistan, and other countries worldwide. The findings demonstrate that the global pandemic has had a notable impact on the industrial production of the World, the United States, and Pakistan, with an initial increase followed by a gradual decline. The unemployment rates in the United States, Pakistan, and the rest of the world have experienced a substantial decline. Simultaneously, the rate of unemployment has witnessed a notable increase, resulting in significant and adverse effects on the respective economies. The decrease in the Business Confidence Index can be attributed to heightened levels of uncertainty, which in turn have had a detrimental impact on the gross domestic product of the United States, Pakistan, and other countries worldwide. The reduction in imports has resulted in a decrease in the government budget deficit, which has had a notable impact on the economy.     

Exploring the Government's role during COVID-19 through a newly validated scale

The present study aims to explore the perceived role of the government during this pandemic situation. The study, through the perception of general masses examine the government's role during the COVID-19 pandemic. It is believed that this is the first empirical study conducted on this issue. The study was conducted on general masses in the northern part of India. The data was collected from two states, namely, Punjab and Himachal Pradesh having different geographical and cultural base. It confirms preventive and supportive role of the government during this pandemic. The study provides a validated scale for future research on the issue under investigation. The results of this study obtained through newly validated scale can be generalised for evaluating the real performance of the government during this pandemic. Further, the government can also assess its role played at the time of this pandemic.     

COVID-19 and Historical Global Rupture in Latin America

This article contrasts two significant ruptures in globalisation. World War I in 1914 was a significant break from the Latin American export-oriented development that was firmly connected to economic globalisation. This article uses the Argentine case study to reveal the ramifications of the post-1914 global breakdown for the republic's internationally dependent development. It draws comparisons with the current COVID-19 crisis as a significant departure from rapid globalisation. Both events altered the trajectory of international activity. Analysis of the 1914 rupture exposes the parallels with COVID-19 and its potential severity for Latin America's internationally connected development.     

新冠疫情背景下妨害传染病防治罪的解释扩张及其回归

新型冠状病毒肺炎疫情中的法律规范适用带来新视角与新问题,在超越可容忍的社会相当性且有刑事可罚追究必要的场合,我国刑法中妨害传染病防治罪的规范适用值得关注。该罪的对象被限定为"甲类传染病",本次新冠肺炎被列为"乙类传染病",从而该罪存在适用上的瓶颈。司法解释的渐进扩张具有唤醒妨害传染病防治罪和注重公共卫生安全法益保护的一面,但是选取的方式难以与刑事法治相契合。为了更好地实现刑法参与社会治理的功能需求,应当对妨害传染病防治罪采取"立法类型化调整、司法解释适度限制"的组合路径,使刑法规范的社会适应性与刑罚处罚的有限性相融合。     

让全球化的国际与国内协作控制流行疾病传播全球化

随着全球贸易、信息交换兴起,以及观念上隔膜的逐步打破和多年以来各种国际性组织共同进行防治疾病的工作,使得大型传染病防治成为了全球性非传统安全问题的一个分支——公共卫生安全的重要议题。若想妥善解决这一问题,必须具备国内稳定、高效的防控机制和国际积极的合作。本文将从人类健康的全球化视角出发,以流行疾病的自身特点,疾病传播的途径等专业知识为背景,借鉴以往的国际流行传染病治理中的经验及教训,阐述全球化的国际与国内协作对维护人类公共卫生安全的重要性。