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Anikó Lajtai M.Sc. Mátyás Mayer Pharm.D. Ágnes Lakatos Ph.D. Zoltán Porpáczy Ph.D. Attila Miseta M.D. D.Sc. 《Journal of forensic sciences》2016,61(2):573-575
Tanax®(T‐61) is a euthanasia solution commonly used in veterinary medicine in Europe. It consists of three active components: embutramide, mebezonium iodide, and tetracaine hydrochloride. Human consumption of Tanax®(T‐61) is usually associated with suicide attempts. In our 15‐year‐long practice, embutramide was detected only three times but within a short period. First, it was found in the urine of a 42‐year‐old veterinarian, and the other two observations were made in a 16‐year‐old young man. Urine samples were analyzed using Shimadzu Prominence TOX.I.S.II. HPLC–DAD system with online SPE extraction system. Both of the two patients denied any intention to die. These cases show that this veterinary drug may also be considered as potential drugs of abuse. 相似文献
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Jonathan Scher 《Family Court Review》2009,47(1):167-189
Acknowledging the rapid growth of child sexual abuse in the United States, this Note advocates for the recognition of a limited exception to the blanket-hearsay ban on out-of-court statements made by unavailable declarants set out by the Supreme Court in Crawford v. Washington . In order to protect a criminal defendant's Sixth Amendment confrontation right, Crawford requires that hearsay evidence that is "testimonial" in nature be deemed inadmissible if the witness is unavailable and the defendant does not have a prior opportunity to cross-examine the witness against him. However, Crawford noted that, where nontestimonial hearsay is at issue, cross-examination may not be necessary. Accordingly, where a child sexual abuse victim makes statements during a structured or semi-structured forensic interview to a member of a multidisciplinary team, these statements should be deemed nontestimonial and thus admitted into evidence, without requiring cross-examination of the child. Allowing for this exception to the general hearsay ban in Crawford is not only consistent with current precedent, but it is also warranted to promote public policy and to curb the negative impact such abuse has on society. 相似文献
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目的:探讨百令胶囊治疗早期糖尿病肾病(diabetic nephropathy, DN)的作用机制.方法:将60例早期DN患者随机分为百令胶囊组和福辛普利组各30例,治疗3个月.在治疗前后用流式细胞仪检测T细胞亚群,用放射免疫法检测白介素-2(interleukin-2, IL-2)水平.结果: 治疗前福辛普利组和百令胶囊组患者血清IL-2水平、CD4+细胞百分率和CD4+/CD8+比值显著低于正常对照组(P<0.01),CD8+细胞百分率显著高于正常对照组(P<0.01).与治疗前比较,福辛普利组和百令胶囊组患者血清IL-2水平、CD4+细胞百分率显著升高(P<0.01).百令胶囊组患者血清IL-2水平、CD4+细胞百分率显著高于福辛普利组(P<0.01).结论:调节T淋巴细胞亚群和IL-2水平可能是百令胶囊治疗早期DN的重要机制之一. 相似文献
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众所周知,穿鞋足迹的情况分析在刑事案件现场勘察检验中占有相当的比重和地位,而对步法特征的分析又是重中之重。不管是同一人的步幅特征还是步态特征,都具有一定的稳定性,而不同人的步幅特征和步态特征是存在差异的。我们通过对一定数量的穿鞋油墨捺印足迹进行研究,用概率论及数理统计的知识对实验数据进行处理:通过T实验法检验实验对象的各个相应指标的标准差之间的近似,证明了同一人步法特征的稳定表现;通过U实验法检验不同实验对象之间各个相应指标的差异,从而论证了不同人在步法特征表现方面的差异。 相似文献
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目的 研究补肾解毒法对多发性硬化小鼠中枢神经炎症及外周血CD4+ T细胞亚群(Th1、Th2、Th17、Treg细胞)的影响。方法 以实验性自身免疫性脑脊髓炎(experimental autoimmune encephalomyelitis, EAE)模型作为多发性硬化动物模型,以C57BL/6小鼠皮下多点注射髓鞘少突胶质细胞糖蛋白35-55(myelin oligodendrocyte glycoprotein 35-55,MOG35-55)的方法复制EAE模型。将小鼠随机分为正常组,模型组,泼尼松组,中药高、中、低剂量组,每组8只小鼠。模型复制后第30天取小鼠脊髓,光镜下观察各组小鼠脊髓炎性细胞浸润和脱髓鞘等病理改变,流式细胞仪检测小鼠脾脏Th1、Th2、Th17、Treg细胞亚群,ELISA法检测脾脏细胞培养上清液中干扰素-γ(interferon gamma, IFN-γ)、白细胞介素-4(interleukin-4, IL-4)、白细胞介素-10(interleukin-10, IL-10)、白细胞介素-17A(interleukin-17A, IL-17A)水平。结果 中药高剂量组、泼尼松组炎症评分和脱髓鞘评分明显低于模型组(P<0.05)。与模型组比较,中药高剂量组、泼尼松组脾细胞培养后上清液中致炎因子IFN-γ、IL-17A降低明显,而抑炎因子IL-4、IL-10升高明显,Treg比例明显升高,Th1和Th17比例明显降低,差异均具有统计学意义(P<0.05)。结论 补肾解毒法能够调节EAE小鼠失衡的CD4+ T细胞亚群,显著抑制EAE模型的炎性反应。 相似文献
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ANDREW CONNELL 《The Political quarterly》2012,83(3):551-559
This article draws on T H Marshall's celebrated classification of civil, political and social rights to examine the use of the courts by individuals seeking to establish rights to particular forms or models of welfare service provision. It argues that tensions between the collective and individual aspects of social rights, the relationship of social rights to inequality, and the difficulty of quantifying (and therefore enforcing) legitimate expectations, all make the use of litigation to establish social rights intensely problematic. Drawing on the recent UK Supreme Court case of R (on the Application of McDonald) v Royal Borough of Kensington and Chelsea, it goes on to suggest that it is unhelpful to think of social rights in terms of human rights: instead, we would do better to adopt Marshall's emphasis on the citizenship basis of social rights and on the social and political context within which they necessarily exist. 相似文献
59.
东北老工业基地区域科技能力特征浅议 总被引:3,自引:0,他引:3
科技能力是一个系统概念,它的稀缺性和不完全流动性使其具有区位要素①的特征。区域科技能力研究是对区域经济的预决性进行研究的组成部分。量化分析其对区域经济发展所起的作用并剖析东北老工业基地的科技能力特征是从战略上实现东北振兴,从而最终达到区域可持续发展的重要途径。 相似文献
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目的:探讨脾虚证与血清甲状腺激素及下丘脑、胸腺细胞核T3受体的关系。方法:成年SD大鼠32只了随机分为4组(每组8只):A组(正常组)、B组(脾虚组)、C组(治疗组)、D组(自复组)。采用放射配基分析法,测定各组大鼠血清T3、T4、FT3、FT4、 γ-T3 及下丘脑、胸腺细胞核T3受体的含量。结果:B、D组大鼠血清T3、T4、FT3、FT4含量均较A、C组低,有显差异(P<0.05或P<0.01);各且间血清γ-T3 含量无显性差异;B、D组下丘脑、胸腺细胞T3受体含量较A、C组低,有显差异(P<0.01)。结论:血清甲状腺激素及下丘脑、胸腺细胞核T3受体的水平降低,可导致甲状腺激素生物效应低下,经由神经内分泌免疫调节环路,削弱免疫功能,这可能是脾虚证的一种重要病机。 相似文献