吉林省科技能力现状及其成长路径研究

科技能力供给的短缺,将迫使区域生产结构服从“短边规则”,保持低水平均衡,这对吉林省科技能力板块进行系统研究提出要求,吉林省科技能力现状及其成长路径的培养和识别将对区域发展起到积极的促进作用。     

Science and Technology for Economic Growth. New Insights from when the Data Contradicts Desktop Models1

Science and technology policy initiatives in the early 1980s have focused in both the United States and Western Europe on improving capacity to apply a good science base in practice, expecting increases in technological advancement, improved market presence and enhanced economic growth. Results varied broadly in the United States and Europe. Even more puzzling, Japan charged ahead in technological advancement without that strong of a science base of its own. Some industrialized economies do not conform to the expected science–technology relationship, whereby strong performance in science shall lead to strong technological performance. The puzzling science–technology relationship in advanced countries has plausible explanations. (1) Science–technology relationship is much interdependent or symbiotic. Its strength and primary direction at a given time varies largely by field of science or technological innovation and across long periods of time. (2) Science–technology link in a country may depend on the overall scientific and technological level of development in that country. The strength and interdependent nature of this link evolves historically and varies across fields of science and technology. The strength of the link is affected by scientific and technological specialization in a country. Different technological fields have different scientific intensities, or degrees of building upon the science base. (3) Specialization of countries across scientific and technological fields varies. Hence, the strength of science–technology link differs between countries. High technological specialization of a country may impact its technological performance more than its immediately current scientific performance does. History, tradition and knowledge transfers may affect more returns on R&D expenditures than the actual value of R&D funds spent in science or technology. Explanations of puzzling behavior of science–technology link may become policy recommendations.     

蜂毒素诱导人T淋巴细胞白血病细胞株6T-CEM的凋亡作用

目的：探讨蜂毒素诱导人T淋巴细胞白血病细胞株6T－CEM的凋亡作用。方法：利用DNA断裂点标记法（TUNEL）、DNA凝胶电泳、活细胞拒染以及光镜方法研究6T－CEM细胞的凋亡。结果：5μg/ml蜂毒素作用4h及4μg/ml蜂毒素作用24h诱导6T－CEM出现明显的凋亡特征。结论：蜂毒素在杀伤6T－CEM的同时能明显诱导细胞凋亡。     

人参皂苷Rg1抑制小鼠实验性自身免疫性脑脊髓炎的作用及免疫机制

目的观察人参皂苷Rg1对实验性自身免疫性脑脊髓炎(experimental autoimmune encephalomyelitis,EAE)的抑制作用及其对脾淋巴细胞T细胞亚群和外周血细胞因子水平的影响。方法采用C57BL/6小鼠皮下多点注射MOG35-55、百日咳毒素的方法复制EAE模型。将EAE小鼠随机分为模型组,人参皂苷Rg1低、中、高剂量组,同时设置正常对照组,每组6只。首次免疫后第10天予以不同剂量Rg1腹腔注射,连续给药14 d。第35天处死小鼠后取脊髓,观察各组小鼠脊髓炎症细胞浸润和脱髓鞘等病理变化,采用流式细胞仪检测小鼠脾淋巴细胞Th1、Th17、Treg细胞亚群,采用ELISA法检测外周血白细胞介素(interleukin,IL)-17A、干扰素γ(interferon gamma,IFN-γ)、IL-6、IL-10水平。结果与模型组比较,人参皂苷Rg1低、中、高剂量组小鼠神经症状评分显著下降(P<0.05),脊髓炎症细胞浸润评分和脱髓鞘评分显著降低(P<0.05),脾淋巴细胞CD4+、CD8+、Th1、Th17 T细胞亚群比例显著降低(P<0.05),Treg(CD4+CD25+FoxP3+)比例显著升高(P<0.05),外周血IFN-γ、IL-17A、IL-16水平显著降低(P<0.05),IL-10水平显著升高(P<0.05),人参皂苷Rg1的作用呈现明显的剂量依赖性。结论人参皂苷Rg1可显著改善EAE小鼠的临床症状,减轻中枢神经系统脱髓鞘和炎症细胞浸润,其作用可能与调控Th17、Th1、Treg细胞亚群失衡,抑制炎症细胞因子表达相关。     

Law Like Poetry – Burnt Norton

Poetry and law are usually cast in opposition but there is a little regarded dimension of responsiveness in law which would incline them towards similarity. The opposition and the similarity are amplified in various instances. Then similarity is affirmed in an involvement in the first of T.S. Eliot'sFour Quartets, ``Burnt Norton'. This revised version was published online in August 2006 with corrections to the Cover Date.     

桦褐孔菌多糖对感染弓形虫小鼠CD4~+和CD8~+ T淋巴细胞亚群的影响

将40只昆明种小鼠随机分成4组:空白对照组、阴性对照组、蒿甲醚组和桦褐孔菌多糖组,每组10只.每组小白鼠腹腔接种弓形虫RH株速殖子1 × 102个,建立小鼠急性弓形虫感染模型.采用流式细胞仪检测脾中CD4+、CD8+T细胞百分数及CD4+/CD8+T细胞比例,探讨了桦褐孔菌多糖对感染弓形虫小鼠CD4+、CD8+T淋巴细胞亚群的影响.结果显示,桦褐孔菌多糖组中CD4+T细胞百分数及CD4+/CD8+T细胞比例与其他3组比较差异极显著(P<0.01);阴性对照组CD8+T细胞百分数显著高于桦褐孔菌多糖组(P<0.05),与其他2组比较差异极显著(P<0.01).结果表明,桦褐孔菌多糖可有效调节感染弓形虫小白鼠的CD4+T细胞百分数及CD4+/CD8+比例,达到抗弓形虫目的.     

The Limits of Political Citizenship

Policy makers tend to focus on the extension of citizenship as the primary means by which new populations become incorporated into a society. Although acquiring formal citizenship is necessary in order to participate in many aspects of a state's civic, social, and political life, the extension of legal citizenship is far from a guarantee for full membership. Instead of focusing exclusively on naturalizing immigrants, we need to consider T.H. Marshall's three spheres of citizenship—the civil, political, and social. By extending social elements of citizenship prior to or at the same time as we extend other benefits, we will move towards more complete citizenship for and greater civil and political engagement among all residents in our society—non-citizens, naturalized, and native-born, alike.

《云南省公安民警预防HIV／AIDS教育及对高危人群管理的能力建设》项目预调查报告

针对目前公安民警普遍缺乏艾滋病防范知识的情况 ,为适应公安工作的实际需要 ,减少艾滋病的发展蔓延及加强对高危人群流动的管理工作 ,有必要对公安民警加强HIV/AIDS预防教育 ,以提高民警的自我保护能力及对高危人群的管理水平 ,我校与省公安厅、省教育厅、省卫生医疗机构合作 ,向国家项目办联合申报了《云南省公安民警预防HIV/AIDS教育及对高危人群管理的能力建设》科研项目 ,并获批准。依据来自本预调查报告。     

Measuring Technological Change in Greece

This paper uses the Growth Accounting methodology to estimate technological change, as well as labor and capital productivity in the various sectors of the Greek economy over the period 1988–1998. The results show that the technological level, as measured through annual growth in Total Factor Productivity, has remained practically unchanged. Meanwhile, technological change accounts for about 40% of economic growth, which is slightly lower compared with the relative performance of other O.E.C.D. countries. Finally, our main findings are, in general terms, consistent with estimates by other researchers.      

鸡T淋巴细胞和B淋巴细胞分离纯化方法的建立

将鸡胸腺和腔上囊淋巴组织剪碎后与PBS磷酸盐缓冲液混合,通过密度梯度离心和尼龙棉柱过滤对T、B淋巴细胞进行了分离纯化。纯化的T、B淋巴细胞以FITC标记的鼠抗鸡CD4单抗,RPE标记的鼠抗鸡CD8单抗,FITC标记的鼠抗鸡Bu-1单抗染色,用流式细胞仪分类检测其纯度,用台盼蓝排斥试验检测T、B淋巴细胞的活力。结果表明,以本研究建立的方法分离到的T、B淋巴细胞纯度较高(均达90%以上),细胞活力强,与流式细胞仪分选的效果相当,且经济简便。