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41.
本文应用十二烷基硫酸钠—聚丙烯酰胺凝胶电泳(SDS-PAGE)首次对细粒棘球绦虫六钩蚴排泄分泌(ES)抗原的多肽组分进行了分析并同时对牦牛源棘球蚴原头节可溶性粗抗原的多肽组分进行了分析。应用10%凝胶,采用垂直板型电泳、考马斯亮蓝R-250染色进行SDS-PAGE的结果表明,六钩蚴ES抗原至少由14种多肽组分组成,分子量范围270~17.5KD,其中主要组分6种。原头节可溶性粗抗原至少由25种多肽组分组成,分子量范围230~17KD,其中主要组分13种。本项研究为功能性抗原的进一步分析、分离奠定了基础。 相似文献
42.
Steven F. Messner 《Journal of Quantitative Criminology》1992,8(2):155-173
This paper examines the common practice in cross-national research on homicide of using crime estimates for a multiyear period based on a smaller number of years than theoretically desired because of erratic data reporting for selected nations. Correlations between hypothetical baseline rates and various alternative estimates are examined to simulate the potential consequences of using temporally incomplete data rather than data for the full multiyear period of interest. The results reveal that this common practice is likely to be highly acceptable for certain national samples but less acceptable for others. The paper concludes with suggestions for dealing with potentially problematic cases. 相似文献
43.
44.
Methodological aspects of the Dutch National Threat Assessment 总被引:1,自引:0,他引:1
Peter Klerks 《Trends in Organized Crime》2007,10(4):91-101
This paper discusses issues related to measuring organized crime as they have become manifest in the Dutch contribution to
the EU Organised Crime Threat Assessment (OCTA). It intends to convey to a wider academic community certain issues of definition,
methodology and accountability, understanding the NTA process in terms of the communication of risks in a context of competitive
defining institutions.
相似文献
Peter KlerksEmail: |
45.
Donell Holloway Manzurul Alam Arthur Griffiths David Holloway 《Australian Journal of Public Administration》2012,71(1):20-32
This article investigates the implementation of key performance indicators (KPIs) in Western Australia's public mental health system. A nationally agreed performance measurement framework forms part of the much needed reform now taking place within Australia. However, progress in the effective monitoring and reporting of KPIs is slow in most states, including Western Australia. The authors report on the results of a selective case study involving semi‐structured interviews with mental health administrators and offer a more nuanced insight into the intricacies and difficulties involved in performance measurement reform. The principal finding is that effective performance measurement and reporting can be internally problematic, particularly within a fragmented and networked system. This tends to give rise to a conformance‐only approach to performance measurement. 相似文献
46.
《Justice Quarterly》2012,29(1):147-162
The errors associated with measuring the number of militia and patriot groups may cast doubt on conclusions drawn from prior studies of the spatial variation of these movements. Most studies of militias have been qualitative investigations of a single group, state, or region. A growing number of studies, however, have used quantitative techniques to assess the hypothesis that the number of militia groups by state covaries with structural and cultural forces. We outline a number of concerns with the validity of the counts, conducted by the Anti‐Defamation League and the Southern Poverty Law Center, used by these studies. We re‐estimate models from previous studies using the four alternative measures of these groups employed in prior studies. We find that many inferences drawn for identical theoretical models differ based upon the measure used. These discrepancies apply not simply to tangential control variables but to indicators of key theoretical constructs. In other words, the decision as to whether or not a particular theoretical framework receives empirical support often depends upon which measure of the dependent variable is used. This suggests that the inconsistent findings in prior research may be due to measurement error and makes it difficult to assess the validity of the conclusions drawn from these studies. It is important to be aware of these weaknesses since scholars studying political crimes and related phenomena often use information from similar sources, making this specific example relevant to a more general area of research. 相似文献
47.
Margaret H. Lloyd Sieger Jessica Becker Kelly Earles Karin Thompson-Wise Kaitlin Hagain 《Family Court Review》2023,61(3):586-601
In 2019, the family treatment court (FTC) best practice standards (the Standards) were published to clarify attributes of FTC programs associated with superior child, parent, and family outcomes. The Standards cover the breadth of FTC operations including program structure and leadership, substance use treatment and complementary services, and behavioral responses to participants. This study aimed to develop an instrument (the Model Standards Implementation Scale; “MSIS”) that stakeholders can use to assess implementation of the Standards by individual FTCs. The MSIS balances usability with scientific validity. Interrater reliability (IRR), internal consistency, and several types of validity were assessed. Results indicated moderate to strong IRR, high internal consistency, mixed known groups validity depending on Standard, and high convergent and divergent validity. Initial findings suggest good validity and usability of the MSIS for evaluating FTC Standards' implementation. Notably, the process of using the tool functioned to educate FTC team members on the Standards. Although implementation of the MSIS is a resource-intensive process, the opportunity to receive constructive feedback proved to be an effective incentive for initial and subsequent participation in the evaluation among FTCs. Future research is needed to examine predictive validity, including association between Standards' implementation and family outcomes in FTCs. 相似文献
48.
Understanding the changing role of public sector performance measurement in less developed countries
This article develops a framework for understanding changes in the demand for and supply of performance information in public sector organizations in less developed countries (LDCs). New Institutional Sociology (NIS) is used to argue that pressures from specific stakeholders stimulate organizations to produce particular performance information. The article distinguishes three groups of stakeholders (i.e. funding bodies, statutory boards and purchasers), and elaborates on the performance dimensions these stakeholders are interested in. The group of funding bodies, with their interest in financial performance information, used to be the most important group of stakeholders. However, statutory boards and purchasers are gaining importance as a result of recent public sector reforms, which include decentralization, marketization and the implementation of anti‐corruption programs. As a consequence of pressures coming from these stakeholders, new performance dimensions, such as the quality and quantity of services and the political governance structure, will be added to organizations' performance measurement (PM) systems. Whether these and other—often more traditional financial—performance dimensions will be balanced and integrated throughout organizations depends on the power positions of the various stakeholders. The arguments presented in this article intend to stimulate public sector organizations in LDCs to design and redesign PM systems as a response to changing stakeholder interests. Copyright © 2010 John Wiley & Sons, Ltd. 相似文献
49.
田刚 《浙江省政法管理干部学院学报》2020,34(3):63-76
刑法对网络安全的保护立场,正由网络运行安全转向网络信息安全。刑事立法更新不断增设网络信息安全专属罪名的同时,刑事司法的定量评价体系却未能一体构建,成为网络安全刑法保护的薄弱环节。当前网络信息安全犯罪的定量评价体系缺乏明确的逻辑主线,同时适用错位的“传统法益侵害程度”量化标准和模糊的“数据规模”新型量化标准,无法满足网络信息安全专属罪名司法适用的准确性和统一性需求,导致了司法适用的困境。消弭规范和技术之间的差异,以“信息规模”为定量评价核心的基础上,建构信息价值的分层评价模型,并将“组信息”作为基础的数据规模计量单位,是大数据时代背景下,突破网络信息安全犯罪司法定量评价困境的合理路径。 相似文献
50.
目的 观察针刺联合生物反馈治疗盆底松弛型便秘的临床疗效。方法 将60例盆底松弛型便秘患者随机分为研究组和对照组。研究组30例,采用生物反馈疗法联合针刺支沟、大肠俞、肾俞、长强、天枢、八髎等穴位;对照组30例,仅予以生物反馈治疗。治疗前和治疗至少1个疗程后,分别进行临床症状评分、肛管压力测定和Glazer评估。结果 两组便秘疗效比较,差异有统计学意义(P<0.05),研究组便秘疗效明显优于对照组。在降低排便费力、排便间隔、肛门直肠阻塞感积分,升高肛门直肠最大收缩压和最大耐受量,以及升高盆底表面肌的快速收缩值、耐受测试值及持续收缩值方面,研究组均明显优于对照组(P<0.05)。结论 针刺联合生物反馈治疗对盆底松弛型便秘疗效确切。 相似文献