血中氯胺酮的液液提取及GC／ECD检测

通过采用液液提取技术以安定为内标对血中氯胺酮进行检验研究,同时考查了各种因素对提取率的影响,表明血中氯胺酮的最佳提取条件是:在pH10.8的碱性条件下,用乙醚提取,回收率为85.5%,最小检出限可达35ng/mL,并通过中毒实验,对中毒兔的血检材进行了分析,证明该方法准确、灵敏、可用于氯胺酮吸毒的认定。     

就业平等权的法律保护

形形色色的就业歧视现象说明,目前我国公民的就业平等权保护不足。这种情况不利于维护我国法律的权威,不利于维护稳定的法治秩序,也不符合就业平等权保护的国际化潮流。应当从我国实际情况出发,借鉴其他国家的经验,加强对公民就业平等权的法律保护,为此需要从完善立法、加强执法、司法等方面采取有效措施。     

中毒死者体内毒鼠强的GC/MS-SIM分析

一 1 9岁男子赌气吞服一白色粉末 ,1 0min后口鼻流血、抽搐 ,迅速送医院 ,经催吐、透析等方法治疗 5天后死亡。根据中毒症状和经验怀疑为毒鼠强中毒。用GC/NPD检验肝中毒鼠强有干扰。改用GC/MS -SIM法分析 ,心血、肝和胃组织中全部检出毒鼠强 ,浓度分别为 0 5 1 μg .mL- 1、0 4 5 μg .g- 1和 0 33μg .g- 1,和文献结果在同一水平。GC/MS -SIM对复杂检材中低含量毒鼠强测定具有更高的选择性 ,也具有较高的灵敏度 ,同时进一步证实毒鼠强排泄较慢 ,经过较长时间后在体内分布比较均匀     

监狱人民警察队伍专业化建设的理性思考

监狱警察专业化是维护监狱安全稳定、提高行刑效率和改造质量、实现司法公正的基本保障,也是推进社会主义监狱法治和现代化建设的内在要求。监狱警察队伍专业化建设的基本思路,旨在从新的视角调整监狱警察结构;在管理机制上有新的探索;在教育培训上有新的突破;在专业化分类上有新的拓展。     

对故意传播艾滋病的刑事立法刍议

保障艾滋病病毒感染者和艾滋病病人的合法权利,使其得到应有的治疗,并规定他们应承担的避免将艾滋病毒传染给他人,包括亲人的义务。政府必须加快制定HIV感染者病人的行政和刑事管理法规,对“传播艾滋病罪”作出规定。     

艾灸督脉组穴对血管性痴呆大鼠海马p38 MAPK信号通路及细胞凋亡的影响

目的 基于p38丝裂原活化蛋白激酶(mitogen-activated protein kinase, MAPK)通路探究艾灸督脉组穴对血管性痴呆(vascular dementia, VD)大鼠的脑保护机制。方法 将60只SPF级健康雄性SD大鼠随机分为假手术组(12只)和实验组(48只);实验组大鼠采用双侧颈总动脉永久结扎法复制VD大鼠模型,随后将模型复制成功的大鼠分为模型组、艾灸组、阻滞剂组、艾灸+阻滞剂组,每组12只;艾灸组大鼠取“百会”“大椎”“风府”穴,采用温和灸法治疗,每次30 min,每日1次,治疗6 d,休息1 d,连续治疗4周;阻滞剂组在模型复制前30 min腹腔注射p38 MAPK阻滞剂(10μmol/L SB203580),模型复制成功后隔日注射1次,每次每只大鼠按1 mL/kg注射10μmol/L SB203580,连续注射4周;艾灸+阻滞剂组大鼠在阻滞剂组干预方法基础上进行艾灸治疗。采用Morris水迷宫实验检测大鼠认知功能,TUNEL法检测大鼠海马组织CA1区神经元凋亡率,Western blot法和RT-qPCR法分别检测大鼠海马组织CA1区p38 MA...     

电针激活Nrf2/HO-1通路抗帕金森病模型小鼠氧化应激的机制研究

目的 观察电针“风府”“太冲”“足三里”穴对帕金森病(Parkinson’s disease, PD)模型小鼠大脑纹状体中酪氨酸羟化酶(tyrosine hydroxylase, TH)、核因子E2相关因子2(nuclear factor-erythroid 2-related factor 2,Nrf2)、血红素加氧酶-1(heme oxygenase-1,HO-1)水平的影响,探讨电针治疗PD的可能机制。方法 将30只小鼠按随机数字表法分为对照组、模型组和电针组,每组10只。模型组、电针组小鼠按照30 mg/kg腹腔注射1-甲基-4-苯基-1,2,3,6-四氢吡啶(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, MPTP)制备PD小鼠模型。电针组小鼠给予“风府”“太冲”“足三里”穴电针干预,每日1次,每次30 min,连续干预12 d。其余两组小鼠不予任何干预。采用爬杆实验和悬挂实验观察3组小鼠行为学改变,旷场实验观察小鼠自主运动总路程,免疫组织化学法检测小鼠大脑纹状体中TH表达水平,实时荧光定量PCR法检测小鼠大脑纹状体中Nrf2、超氧...     

The Impact of Language Status as an Acculturative Stressor on Internalizing and Externalizing Behaviors among Latino/a Children: A Longitudinal Analysis from School Entry through Third Grade

This study examined the relationship between limited English proficiency status, and internalizing and externalizing behaviors among a sample of Latino/a children (N = 2,840) from the US Department of Education’s Early Childhood Longitudinal Study, Kindergarten (ECLS-K) data set. Results of cross sectional regression and hierarchical linear modeling (HLM) analyses suggest that there is a positive relationship between limited English proficiency and externalizing symptoms, particularly by third grade. Additionally, sex and place of birth also helped to explain externalizing behaviors at various time points in the models. Place of birth and family poverty were significantly associated with internalizing symptoms. Implications for future research and interventions related to internalizing and externalizing behavior among the Latino/a school aged population are discussed.

Comparing Putin’s and Brezhnev’s Policies toward the Middle East

This article compares Moscow’s and Washington’s foreign policies toward the Middle East in 1982 and 2008. In 1982, Moscow and Washington each had a distinct set of friends and foes. In 2008, Washington still has a distinct set of friends and foes, but Moscow has relatively good relations with all governments and most major opposition movements in the region—the only exceptions being Al Qaeda and its affiliates. It is argued that Putin’s policy toward the Middle East is not really aimed at displacing the U.S. in the region, but protecting Russia and Russian interests from Al Qaeda and its allies. Indeed, a continued American presence in the region serves to protect Russian interests in the region.