A Fatal Case of Poisoning with Fentanyl Transdermal Patches in Japan

Fentanyl transdermal patches have been used to treat cancer‐ and noncancer‐related chronic pain. However, its inappropriate or illegal application may cause fatal poisoning. We herein present the case of a Japanese woman in her 40s who was found dead with seven 25‐μg/h fentanyl transdermal patches on her body. We established a detailed toxicological analysis procedure to quantify fentanyl, and its metabolite norfentanyl, and other drugs (acetaminophen, allylisopropylacetylurea, celecoxib, estazolam, promethazine, and sertraline) in human whole blood by ultra‐high‐performance liquid chromatography–tandem mass spectrometry. The measured fentanyl and norfentanyl concentrations in the femoral and cardiac blood were 0.051 and 0.072 μg/mL and 0.033 and 0.076 μg/mL, respectively. The decedent's fentanyl concentrations were consistent with previously reported postmortem blood levels for fatal cases of poisoning by fentanyl transdermal patches. Based on the decedent's case history, autopsy findings, and toxicological analyses, the cause of death was identified as intoxication with transdermal fentanyl.     

Understanding and Measuring Consumption Motives in the Performing Arts

Currently, there is no common understanding of categorizing, conceptualizing, and measuring consumption motives in the performing arts. Study one presents the results of forty-seven semi-structured, in-depth interviews and deepens the understanding of consumption motives. A new framework consisting of cultural and social motives is introduced. This framework is tested in the second study. Here, a quantitative instrument is developed. The results of the principal components analysis refine the framework and demonstrate the following consumption motives: cultural aesthetics (with two dimensions: artistic value and enjoyment of beauty), cultural relaxation, cultural stimulation, social bonding, social attraction, social distinction, and social duty.     

An initial evaluation of the Global Review Form as an approach to measuring individual change

Background: Routine assessment of individual change in forensic mental health services is increasingly recognised as important. However, existing tools have been criticised and their periodic use make them unsuited to directly measure the impact of interventions. This paper describes the initial evaluation of the Global Review Form (GRF) as a framework for measuring change over time. Specifically, measurement properties, feasibility and usefulness in routine practice are examined. Method: 28 male service users in three distinct areas of an adult secure service (low secure, locked rehabilitation and high relational support housing) were rated over a 20-week period by their multidisciplinary teams. Findings: The GRF showed promising construct validity and appropriate stability and sensitivity to change across time. It enabled measurement and understanding of individual change over time. Staff feedback suggested the GRF is a useable and practical outcome measuring tool. Conclusions: The GRF shows promise for use as a routine outcome monitoring tool within forensic mental health services.     

监狱工作法制化的内涵及其外化表现

监狱工作法制化就是要形成完备的法律、法规、规章体系,把监狱的全部工作纳入法制化的轨道,依法管理,规范运行,切实做到依法治监.为实现监狱工作法制化,必须构建完备的监狱法律体系,培养高素质监狱管理人员,建立专门的监狱法制工作机构,构筑现代监狱行刑机制.     

GC/MS测定尿液中氯胺酮含量不确定度评定

目的评定气相色谱—质谱法（GC/MS）测定尿液中氯胺酮含量的不确定度。方法依据不确定度评定的指导性文件,从测定程序分析了不确定度的来源,量化不确定度分量,计算检测结果的合成标准不确定度和扩展不确定度。结果尿液检材中测定结果平均值为0.257μg/mL的扩展不确定度为0.016μg/mL。结论尿液中氯胺酮含量的不确定度主要来源于标准品纯度和标准曲线。     

超高效液相色谱-串联质谱法同时测定尿液中16种抗生素

目的 建立同时分析尿液中16种抗生素的超高效液相色谱-串联质谱(UPLC-MS、MS)方法.方法 以哌拉西林为内标.尿样中的目标化合物经Oasis HLB固相萃取柱富集、纯化,利用ZORBAX SB-C18色谱柱,以0.1%的甲酸溶液-乙腈为流动相经梯度洗脱分离,采用多反应监测(MRM)模式进行分析.结果各化合物的最低...     

喷墨打印机走纸步进量作为机种特征的实验研究

目的确定一个有助于识别喷墨打印机种的墨迹特征。方法对Epson、HP、Canon和Lexmark四大品牌的65种喷墨打印机的实验输出样本墨迹中重复出现的瑕疵进行分析。这些瑕疵包括：横向漏白条纹、重叠条纹和纵向对接错位等。结果相邻两个瑕疵之间的距离与打印机固有的走纸步进量直接相关。观测得出的走纸步进量既稳定又反映特定机种。结论将走纸步进量作为一个喷墨打印机种特征来利用具有较强的有效性和可行性。     

公务员情绪智力与工作绩效关系及开发实证研究

根据研究假设,以347份问卷调查结果对公务员情绪智力与其工作绩效的关系进行实证研究。研究结果表明:公务员情绪智力中的自我觉知、自我管理、社会觉知和社交技巧四个维度对任务绩效和关系绩效均有显著正向影响,这四个维度的不同表现水平,将带来公务员工作绩效的差异。据此,为了有效提升公务员情绪智力水平,本文从编制情绪智力词典、开发情绪智力测评体系、个人发展、组织发展等角度提出了对策建议。     

大学生诚信影响因素的解析结构模型研究

基于层次分析法,从自身因素、家庭环境、学校环境和社会环境四个一级指标,构建大学生诚信的影响因素指标体系,充分考虑各因素之间存在的错综复杂的影响关系,借助解析结构模型（ISM）,建立大学生诚信影响因素的层次递阶结构,找出大学生诚信的最根本影响因素是家庭经济条件、社会环境、网络与媒体导向、学校监督力度和校内利益分配,并根据影响因素的层次结构,从家庭、学校、社会三个方面提出了加强大学生诚信教育的对策。