Sickle cell trait-associated deaths: a case series with a review of the literature

This study presents a series of 16 carriers of hemoglobin S (HbS) who died during various circumstances. Many of the cases were associated with mild to moderate exertion. The onset and/or duration of symptoms varied from a few minutes to several hours with many displaying a prolonged lucid interval with stable vital signs. Despite seeking medical treatment, sickle cell trait-related micro-occlusive crisis was never considered in the differential diagnosis. Several cases were associated with sudden death. In those deaths which were delayed, high anion gap and uncompensated metabolic acidosis were typical and were not heat related. Also characteristic were large increases in creatine kinase, alanine aminotransferase, and aspartate aminotransferase along with myoglobinemia. Although the antemortem diagnosis of rhabdomyolysis was made, the underlying cause was never deduced by the clinicians. The sickling found at autopsy is not always a postmortem artifact, and in the right circumstances can be diagnostic.     

加强公安科技队伍建设是落实科技强警战略的当务之急

公安科技队伍是公安队伍的重要组成部分,在落实科技强警战略、促进公安工作发展中起着举足轻重的作用。当前,公安科技队伍的建设现状还不能满足公安工作的现实要求。公安科技队伍中,人才数量不足、管理政策不明、整体素质不高、创新能力不强仍是制约公安科技发展的"瓶颈"因素。因此,要着力解决好以下问题:一是公安科技队伍的内涵界定与科学分类;二是公安科技队伍的现状及影响因素分析;三是公安科技人员的基本管理制度建设;四是公安科技队伍的评价激励机制设计;五是公安科技队伍的发展战略与对策研究。     

Rapid Identification of Synthetic Cannabinoids in Herbal Incenses with DART‐MS and NMR

The usage of herbal incenses containing synthetic cannabinoids has caused an increase in medical incidents and triggered legislations to ban these products throughout the world. Law enforcement agencies are experiencing sample backlogs due to the variety of the products and the addition of new and still‐legal compounds. In our study, proton nuclear magnetic resonance (NMR) spectroscopy was employed to promptly screen the synthetic cannabinoids after their rapid, direct detection on the herbs and in the powders by direct analysis in real time mass spectrometry (DART‐MS). A simple sample preparation protocol was employed on 50 mg of herbal sample matrices for quick NMR detection. Ten synthetic cannabinoids were discovered in fifteen herbal incenses. The combined DART‐MS and NMR methods can be used to quickly screen synthetic cannabinoids in powder and herbal samples, serving as a complementary approach to conventional GC‐MS or LC‐MS methods.     

The Use of Laser Microdissection in Forensic Sexual Assault Casework: Pros and Cons Compared to Standard Methods

Sexual assault samples are among the most frequently analyzed in a forensic laboratory. These account for almost half of all samples processed routinely, and a large portion of these cases remain unsolved. These samples often pose problems to traditional analytic methods of identification because they consist most frequently of cell mixtures from at least two contributors: the victim (usually female) and the perpetrator (usually male). In this study, we propose the use of current preliminary testing for sperm detection in order to determine the chances of success when faced with samples which can be good candidates to undergo analysis with the laser microdissection technology. Also, we used laser microdissection technology to capture fluorescently stained cells of interest differentiated by gender. Collected materials were then used for DNA genotyping with commercially available amplification kits such as Minifiler, Identifiler Plus, NGM, and Y‐Filer. Both the methodology and the quality of the results were evaluated to assess the pros and cons of laser microdissection compared with standard methods. Overall, the combination of fluorescent staining combined with the Minifiler amplification kit provided the best results for autosomal markers, whereas the Y‐Filer kit returned the expected results regardless of the used method.     

植物SSR标记的研究现状及其在法庭科学中的应用

随着SSR分子标记技术的深入研究,其在植物遗传多样性分析、种属鉴定、个体识别中得到越来越广泛的应用。本文就植物SSR分子标记技术的特性、发展、研究现状进行综述,并探讨其在法庭科学中的应用前景,旨在为法庭科学和相关学科中的应用和相关领域中的研究提供参考。     

Psychopathy and Female Gender: Phenotypic Expression and Comorbidity; A Study Comparing a Sample of Women Hospitalized in Italy's Maximum Security Facility with Women Who were Criminally Sentenced and Imprisoned,

Various studies have shown that women with psychopathy tend to commit crimes that are less violent than those of psychopathic men. The present study was designed to address the influence of psychopathy on the crimes committed by female offenders. A national sample of female offenders found NGRI or of diminished responsibility and at risk for criminal recidivism (OPG patients) was compared with a sample of female offenders who were convicted and imprisoned. Results of this comparison between the two groups of female offenders indicate that psychopathy is a transversal psychopathological dimension which may or may not be associated with other mental disorders. In both samples, the most commonly reported offenses among women with high PCL‐R scores were minor offenses, not particularly violent, but they appear to be related to typical psychopathic features such as superficial charm, pathological lying, and manipulation.     

全二维气相色谱在刑事技术中的应用

综述了近年来发展起来的全二维气相色谱(GCхGC)技术正交分离系统原理及其特点以及在刑事技术中应用的发展前景。     

党的第三代中央领导集体对邓小平教育思想的继承和发展

邓小平教育思想博大精深 ,内容丰富 ,以江泽民为核心的第三代领导集体在继承其合理内核的基础上 ,根据条件变化进行了新的发展 :在邓小平的教育要优先发展的思想基础上 ,明确提出了科教兴国战略 ;在邓小平的“三个面向”指导思想下 ,强调进一步深化教育改革 ,全面推进素质教育 ;同时 ,还十分重视终身教育和远程教育     

鉴定人的责任负担

鉴定人是司法鉴定活动的决定性因素。鼓励专家参与法庭服务与约束专家独立、客观实施鉴定这一对矛盾需要通过制度的合理设置达到一定的平衡状态,以适合诉讼活动的开展。鉴定人的责任负担是体现对鉴定人实施鉴定活动进行约束的主要手段,也是我国进一步深化司法鉴定体制改革不可回避的重要内容之一。     

国有企业及科教文卫等行业行政化管理与“官本位”问题研究

由＂官本位＂衍生出来的泛行政化管理已成为影响和制约我国国有企业和科教文卫行业科学发展的最大阻力之一。本文在对我国国有企业及科教文卫等行业行政化管理的表现、问题、产生＂官本位＂的原因、危害进行分析的基础上,借鉴国内外人力资源管理开发的经验与教训,为在这些企业、行业有效防止和克服＂官本位＂消极影响提出了一些对策与建议。