中小城镇发展问题的反思与转变

分析我国城市发展“小城镇，大问题”、“小城镇，大发展”、“小城镇，大战略”转变历程，反思中小城镇发展问题的战略路径，在新型城镇化背景下，重新回归到研究增强中小城镇发展问题上。依据城镇规模等级体系理论，研究得出了中小城镇建设在城镇体系结构和城镇化建设中的战略地位作用，提出了加快中小城镇建设发展的思路，地方政府要优化公共服务，统筹城发乡展，更好引导发挥企业和居民“以足投票”的作用，为完善城市体系结构和城市可持续发展提供新动力。     

Establishing a Social-Darwinist Mentality in Japan’s Paternalist State: The Potential of Resistance by a Counter-Public

ABSTRACT

From a historical perspective, the welfare net in Japan was established from above without democratic participation and expanded only slowly. This expansion in many cases was aimed at enhancing national cohesion, especially during war time. During the current neoliberal era, Japan’s paternalistic welfare state has been able to put into practice the dismantling of national pension and health-care systems without the need for any theoretical re-orientation. In response, counter-publics have engaged in protest and resistance. By doing so, the victims of modernization and those who are socially weak and disadvantaged in multiple ways are able to regain their self-esteem and personal integrity.     

Bacterial Cross‐contamination Potential Associated with Contaminated Currency

Previous studies have shown a significant amount of contaminants on paper currencies. It is important to study the transfer of microorganisms between paper currencies to determine whether it meets the level of a human health threat. This cross‐contamination potential was analyzed by seeding new US 1‐dollar bills with Bacillus thuringiensis, and pressing or rubbing them against clean currency to determine the amount of bacteria transfer to the unseeded currency. The transferred amount of bacteria was recovered, plated, incubated, and the colony‐forming units were quantified. Among the recovery methods tested, the most efficient method, vortexing for 10 min with a recovery efficiency of 40 ± 8.1%, was used in this analysis. The resulting transfer rates were 4.8%, 8.6%, and 14.3% when pressed for 24 h, 72 h, and rubbed together, respectively. These transferred amounts of bacteria are significant and have the potential to spread infectious diseases.     

Justifications for Non-Consensual Medical Intervention: From Infectious Disease Control to Criminal Rehabilitation

A central tenet of medical ethics holds that it is permissible to perform a medical intervention on a competent individual only if that individual has given informed consent to the intervention. Yet it occasionally seems morally permissible to carry out non-consensual medical interventions on competent individuals for the purpose of infectious disease control (IDC). We describe two different moral frameworks that have been invoked in support of non-consensual IDC interventions and identify five desiderata that might be used to guide assessments of the moral permissibility of such interventions on either kind of fundamental justification. We then consider what these desiderata imply for the justifiability of carrying out non-consensual medical interventions that are designed to facilitate rehabilitation amongst serious criminal offenders. We argue that these desiderata suggest that a plausible case can be made in favor of such interventions.     

细菌素在动物疾病防治中的作用和机理研究进展

从细菌素的性质、生产与制备、在动物疾病防治中的作用、抑(杀)菌机理及安全性评价等方面概述了此类由细菌分泌的高效抗菌蛋白类物质的研究进展。认为,细菌素不仅在体外对各种致病菌具有较强的抑杀作用,而且经口服能显著抑制动物胃肠道内的有害菌,腹腔或静脉注射后可防治动物全身性细菌感染,无任何毒害作用,是一类可用于动物疾病防治的理想的抗生素替代品。     

一种新禽病——禽卡氏杆菌病的研究进展

概述了禽卡氏杆菌的病原特征,阐述了该病原在分离培养、流行病学、诊断方法、防控措施以及流行现状等方面的研究进展,包括组织学、免疫学、分子生物学等方面所取得的进展,旨在为研究该病提供理论参考.     

Antibiotics and probiotics in chronic pouchitis:A comparative proteomic approach

AIM:To profile protein expression in mucosal biopsies from patients with chronic refractory pouchitis following antibiotic or probiotic treatment,using a comparative proteomic approach. METHODS:Two-dimensional polyacrylamide gel electrophoresis and matrix-assisted laser desorption/ ionization-time of flight mass spectrometry were used to characterize the changes related to antibiotic therapy in the protein expression profiles of biopsy samples from patients with chronic refractory pouchitis.The same proteom...     

Complex Congenital Heart Malformation Including Transposition of the Great Vessels,Presenting as Sudden Unexplained Infant Death

Transposition of the great vessels (TGV) is a common congenital heart defect that is difficult to diagnose before birth. Antenatal diagnosis is associated with increased survival. Unusual features such as anomalous pulmonary artery origin may delay cyanosis, decreasing clinical suspicion. A three‐week old female infant who had never been cyanotic presented for forensic autopsy due to onset of unresponsiveness at home. History included risk factors for TGV and signs of heart enlargement that were not recognized during life. Cardiac pathology consultation identified D‐type TGV with additional rare anomalies. TGV may present as sudden unexplained infant death (SUID) for forensic autopsy if variant features prevent development of cyanosis. Cardiac pathology consultation is helpful in clarifying these features.     

温病湿热证湿重于热动物模型舌的病理观察

目的：观察温病湿热证湿重于热动物模型舌的病理改变。方法：复制温病湿热证湿重于热动物模型,观察大鼠舌的病理改变,并设湿热组、脾虚组、正常组进行比较。结果：湿重于热组、湿热组固有层乳头密度及核分裂相频数显著增多,与正常组及脾虚组比较差异有显著性;湿重于热组和湿热组固有层均出现炎症、充血及水肿,前者水肿更甚,后者则充血明显。结论：舌的病理改变,可能是湿热证型中舌苔变化的病理基础,并可作为判定湿热轻重的指标之一。     

口蹄疫病毒A/WH/09株结构蛋白P1基因的克隆及其B细胞抗原表位的预测

对口蹄疫病毒(FMDV)A/WH/09株P1结构蛋白基因进行了扩增、克隆及序列测定。结果显示,FMDV A/WH/09株P1基因长2 208bp,包含完整的开放阅读框,编码736个氨基酸,其中VP1长636bp,编码212个氨基酸;VP2长654bp,编码218个氨基酸;VP3长663bp,编码221个氨基酸;VP4长255bp,编码85个氨基酸。采用DNAStar Protean软件对P1蛋白的二级结构、可塑性、亲水性、表面可及性及抗原指数等参数进行了综合分析,并预测其B细胞的抗原表位分布。结果表明,VP1、VP2和VP3上均有多个区域为B细胞抗原优势表位,VP4上也有少量潜在的B细胞抗原表位。与已鉴定的B细胞抗原表位相比,本试验所用方法预测的结果有较高的准确度,是一种较为先进的表位研究方法。