私利·公利·正义·仁义--义利关系的传统反思与现代诠释

本文首先在剖析中西义利观区别的基础上,把义和利的内涵分别分解为私利、公利和正义、仁义等不同层次.然后通过对社会主义市场经济内在本质的考察,提出理解义利关系的三大理论原则第一,以私利为动力,以公利为目标;第二,以正义为约束,以仁义为引导;第三,以利释义,以义制利,义利统一.最后根据以上原则提出社会主义市场经济条件下坚持义利统一的三个层次合理谋利即是义;增进公利即是义;自觉让利即是义.     

丰田零库存管理对我国企业库存管理优化的启示

零库存管理对丰田公司经营的成功发挥了重要作用,对我国现代化企业经营也具有较强的借鉴意义.鉴于我国企业对库存管理存在的认识误区,基于对丰田零库存管理的内涵及应用效果的分析,提出我国企业应学习丰田库存管理的先进经验,避免对零库存管理的认识误区,进一步转变观念、建立新型库存管理模式的观点,并在此基础上针对我国制造业企业在借鉴丰田零库存管理方面提出对策建议.     

猪生殖与呼吸综合征病毒广东株ORF3和ORF5基因的克隆与分析

采用RT PCR方法扩增了猪生殖与呼吸综合征病毒广东株的糖蛋白基因ORF3、ORF5 ,并对其进行了克隆和序列分析。用Blast分析软件比较分析了其与VR 2 332株以及流行的欧洲株之间的同源性 ,并对其编码氨基酸序列的分子质量、等电点、穿膜区、糖基化位点进行了分析。结果显示 ,PRRSV广东株ORF3与美洲株的同源性达 90 % ,而与欧洲株只是在 318～ 393bp、5 0 2～ 6 97bp之间有 77%左右的同源性 ;ORF5与美洲株的同源性为 88% ,与欧洲株仅在 133～ 2 0 9bp区间有 77%左右的同源性。     

Genetic polymorphism at 15 tetrameric short tandem repeat loci in four aboriginal tribal populations of Bengal

POPULATIONS: This study reports the genetic polymorphism observed at 15 short tandem repeat loci D3S1358, TH01, D21S11, D18S51, D5S818, D13S317, D7S820, D16S539, CSF1PO, vWA, D8S1179, TPOX, D2S1338, D19S433, and FGA in four aboriginal populations of Bengal. The analysis was performed to decipher the suitability of CODIS as well as six other highly polymorphic and unlinked markers in Forensic Testing. Studied populations include four tribes: Karmali, Kora, Maheli, and Lodha.     

Medical data breaches: Notification delayed is notification denied

The EU and the United States have implemented data breach notification rules that cover the health sectors. Nevertheless, data breach incidents involving medical data continue to rise, especially in the US and the UK. The HITECH Act, Pub. L. 111-5 Title XIII is the first federal health breach notification law in the US to be characterized by less government intrusions, while the revised EU Privacy Directive, 2009/136/EC calls for tougher privacy protection for data held by electronic communication providers. While the EU law sets a global de facto standard, the law remains toothless without strong enforcement mechanisms.     

Comparison of two methods for isolating DNA from human skeletal remains for STR analysis

Abstract: The quality and efficiency of a standard organic DNA isolation method and a silica‐based method using the QIAGEN Blood Maxi Kit were compared to obtain human DNA and short tandem repeats (STRs) profiles from 39 exhumed bone samples for paternity testing. DNA samples were quantified by real‐time PCR, and STR profiles were obtained using the AmpFlSTR^® Identifiler^® PCR amplification kit. Overall, the silica‐based method recovered less DNA ranging from 0 to 147.7 ng/g (average 7.57 ng/g, median = 1.3 ng/g) than did the organic method ranging from 0 to 605 ng/g (average 44.27 ng/g, median = 5.8 ng/g). Complete profiles (16/16 loci tested) were obtained from 37/39 samples (95%) using the organic method and from 9/39 samples (23%) with the silica‐based method. Compared with a standard organic DNA isolation method, our results indicate that the published silica‐based method does not improve neither the quality nor the quantity of DNA for STR profiling.     

“修改不得超范围”原则法律论争的若干问题

《专利法》第33条规定了"修改不得超范围"原则。但如何理解和适用该原则,专利审查部门与实务界在此原则上存在分歧与争论。例如,关于《专利法》第33条的立法目的之争;关于如何理解"原说明书和权利要求书记载的范围"之争;关于修改原则与修改方式、修改时机之争;关于修改与"禁止反悔"原则的关系之争等。从专利法的原理体系出发,针对上述法律论争做出简要介绍与评论,以期业内全面探讨"修改不得超范围"原则。     

Sudden death in an adolescent due to undiagnosed classic Hodgkin lymphoma

Few cases of natural sudden death presenting as an undiagnosed lymphoma have been reported in the literature, especially in adolescents. Herein we provide a report of sudden death caused by undiagnosed classic Hodgkin lymphoma (cHL). We describe an 18-year-old female who collapsed after several weeks of weight loss, decreased appetite, and dyspnea. At autopsy, a bulky mass arising in the mediastinum and neck compressed the esophagus and trachea, surrounded the great vessels, obliterated the pericardial sac, and infiltrated the myocardium. The lungs were collapsed and large pleural effusions were present. The tumor burden, which weighed at least 2710 g in aggregate, was entirely above the diaphragm. Microscopic examination of the masses showed features typical for nodular sclerosis cHL including large bands of sclerosis, numerous Hodgkin/Reed-Sternberg (HRS) cells, and an eosinophil-rich mixed inflammatory cell infiltrate. Immunohistochemical stains showed the HRS cells to be uniformly positive for CD30 and CD15 and negative for CD3, CD20, CD45, and PAX5. This case exemplifies a rare sudden natural death due to previously undiagnosed cHL in a young patient.