氢氧化铝纳米颗粒对鸡新城疫抗原的免疫佐剂效应

以新城疫病毒为抗原,制备纳米氢氧化铝和常规氢氧化铝佐剂灭活疫苗,分别免疫20日龄雏鸡,比较了免疫后2～24 d的抗体效价和外周血淋巴细胞CD4、CD8分子mRNA的表达水平。结果显示,纳米氢氧化铝佐剂组抗体效价在免疫后第10 d达到峰值,为6.67±0.58,免疫保护期超过9 d,常规氢氧化铝佐剂组抗体效价在免疫后第10 d达到峰值,为4.33±0.58,免疫保护期小于7 d;与常规氢氧化铝佐剂组相比,纳米氢氧化铝佐剂组免疫后4～17 d的CD4以及10～17 d的CD8分子mRNA的表达水平显著提高,在峰值时后者的表达量为前者的2.0和1.9倍。结果表明,纳米氢氧化铝佐剂能辅佐鸡体产生比常规氢氧化铝佐剂更强烈的体液免疫和细胞免疫。     

论WTO对我国经济法制建设的影响及对策

加入WTO,对有中国特色社会主义市场经济登上世界经济舞台,建设成熟的社会主义市场经济法制体系,是机遇大于挑战。我国亟需在相关的立法中进一步深化经济法制的理念,积极健全和完善与WTO经济法律制度相适应的相关法律。加快适应“法治经济”发展的法制建设,是保障我国加入WTO之后实现经济健康、快速发展的关键。     

Sudden death due to an unrecognized cardiac hydatid cyst: three medicolegal autopsy cases

Echinococcosis is a human infection caused by the larval stage of Echinococcocus granulosus. The most common sites of infection are the liver and the lungs. Cardiac hydatid cysts are very rare, even in regions where hydatic cysts are endemic (the Mediterranean, South America, Africa, and Australia). It has been reported that cardiac involvement is seen in about 0.5-3% of human echinococcosis cases. Three cases of cardiac hydatid disease that caused sudden death and which were histopathologically diagnosed are reported. Cardiac echinococcosis is rare, but due to its insidious presentation and affinity to cause sudden death, it is important that it be identified in the histopathological examination.     

Gender Differences in the Impact of Family of Origin Violence on Perpetrators of Domestic Violence

This study examines the applicability of theories related to the intergenerational transmission of violence. Studies of the impact of violence in the family of origin on the propensity to engage in domestic violence as an adult have commonly focused on boys as potential perpetrators. This study examined the impact of previous violent victimization on males and females charged with domestic violence perpetration, finding previous violence significantly related to increased fear and hyper-vigilance to threat in adult relationships. In addition, the study explored the theoretical assertion that those who use violence in their homes are not also generally violent and found that the majority of individuals using violence, both males and females, were not violent outside the home.     

Corporal Punishment and Kids: How Do Parent Support and Gender Influence Child Adjustment?

Previous research on corporal punishment has failed to consider the interaction of parent support and parent gender in predicting child outcomes. The current study examined whether parental support moderated the effects of corporal punishment on child outcomes (i.e., depression and aggression), and more specifically, whether the gender of the supportive parent moderated the effects of punishment from the opposite-sex parent. Results differed depending on the gender of the punishing and supportive parents, suggesting that parental support can be a protective factor in child outcomes but only under certain conditions. Mother support moderated the effects of father punishment on child depression but not child aggression. High corporal punishment by father was related to more child depression at both high and low levels of mother support. High levels of mother support only seemed important (i.e., children were less depressed) at low levels of father corporal punishment. In contrast, father support moderated the relationship between mother corporal punishment and child aggression but not depression. Children with high father support showed less aggression across all levels of mother corporal punishment. At low levels of father support, child aggression increased as mother corporal punishment increased. For depression, mother corporal punishment was positively related to child depression regardless of level of father support. These findings suggest differential effects for mother and father support and have implications for the treatment and prevention of negative outcomes in children who are physically punished by their parents.

Verbal and Physical Aggression in Couples Where the Female Partner is Drinking Heavily

This study evaluated (i) frequencies of aggression in maritally distressed problem drinking (DP) women relative to controls, (ii) aggression, marital satisfaction, and partner drinking in predicting female drinking, and (iii) discrepant within-couple drinking in predicting marital distress. The sample included 27 DP women, 24 maritally distressed nonproblem drinking women (DNP women), and 24 women with neither problem (NDNP women). DP women reported frequencies of physical aggression similar to DNP women, but less male verbal aggression than DNP women. Predictors of female drinking were marital satisfaction and male drinking, but aggression did not predict female drinking. Female marital satisfaction was predicted by interspousal discrepancies in drinking after accounting for verbal aggression.     

The Relationship Between Traumatization and Pain: What is the Role of Emotion?

The role of emotion in the relationship between traumatic experiences and physical pain was examined via path modeling by using a sample of hospital outpatients (N = 138). Most of the participants reported being traumatized (77%) and experiencing chronic pain (69%). Trauma survivors and nontraumatized individuals did not differ significantly on mean symptom scale scores (i.e., depression, anxiety, anger, dissociation, somatization and pain). However, a moderate effect size was found for dissociation. There were also significant associations found between trauma levels and levels of adult symptomatology. Interestingly, sexual abuse was less highly correlated with symptomatology than other types of traumatization, such as neglect. None of the three proposed path models describing the relationship between trauma, pain, and emotion fit the data successfully. Implications are discussed.     

Treatment of Gang Members Can Reduce Recidivism and Institutional Misconduct

Gang violence creates serious safety and security concerns in the community and prisons. Treated gang and nongang members recidivated significantly less in a 24-month follow-up than their untreated matched controls. Treatment consisted of high intensity cognitive-behavioral programs that follow the risk, need, and responsivity principles (Andrews & Bonta, 2003). The treated gang members who recidivated violently after treatment received significantly shorter sentences (i.e. they committed less serious offences) than their untreated matched controls. Untreated gang members had significantly higher rates of major (but not minor) institutional offences than the other three groups. Correctional treatment that follows the risk, need and responsivity principles appears able to reduce recidivism and major institutional misconduct. Effective correctional treatment should be considered as one of the approaches in the management and rehabilitation of incarcerated gang members.     

Mugshot Exposure Effects: Retroactive Interference, Mugshot Commitment, Source Confusion, and Unconscious Transference

More than 25 years of research has accumulated concerning the possible biasing effects of mugshot exposure to eyewitnesses. Two separate metaanalyses were conducted on 32 independent tests of the hypothesis that prior mugshot exposure decreases witness accuracy at a subsequent lineup. Mugshot exposure both significantly decreased proportion correct and increased the false alarm rate, the effect being greater on false alarms. A mugshot commitment effect, arising from the identification of someone in a mugshot, was a substantial moderator of both these effects. Simple retroactive interference, where the target person is not included among mugshots and no one in a mugshot is present in the subsequent lineup, did not significantly impair target identification. A third metaanalysis was conducted on 19 independent tests of the hypothesis that failure of memory for facial source or context results in transference errors. The effect size was more than twice as large for "transference" studies involving mugshot exposure in proximate temporal context with the target than for "bystander" studies with no subsequent mugshot exposure.