浅谈移动通信规划的几个问题

结合在深圳、温州等地区的规划经验 ,总结提炼出在移动通信规划中负荷预测的方法 ,并在局所和管网规划等方面提出了自己的见解和观点 ,对城市移动通信产业的管理及规范发展提供了一些可借鉴的经验。     

慢性阿片依赖者在戒断阶段细胞免疫功能的研究

为科学地鉴定、预防毒品相关死亡提供一定的实验证据，采用免疫组化、细胞培养、核素掺入、ELISA等方法，研究26例用药模式相近的慢性阿片依赖者在戒断阶段的细胞免疫功能，并与健康对照组进行统计比较。结果表明：慢性阿片依赖者戒断期CD＋4细胞数目减少（30．40±9．45％，P＜0．05），CD＋4／CD＋8比例降低（1．27±0．19，P＜0．01）；PBMC合成DNA的能力下降（SI＝8．62±3．20，P＜0．01），产生IL－2的水平降低（23．78±8．77，P＜0．06）和产生IL－6的能力呈降低趋势（468．81±196．40，P＞0．05）；血清中免疫抑制性因子sIL－2R水平显著升高（566．33±265．50，P＜0．01）。慢性阿片依赖者在戒断阶段有多种免疫参数紊乱，细胞免疫功能低下。     

移动电话“靓号”应成为盗窃罪的犯罪对象——全国首例“靓号黑客案”的物权法解读

全国首例“靓号黑客案”二审判定移动电话“靓号”不属于刑法上的财物范畴,从而否定其成为盗窃罪的犯罪对象。这是二审法院受刑法学理论界关于盗窃罪犯罪对象的“有体性说”错误指导的结果。“有体性说”的错误根源在于对民法中无体物与有体物相区分理论的错误理解。我国刑事司法实务界应该主动舍弃“有体性说”,并应从盗窃罪犯罪对象的几个基本特征入手,认定移动电话“靓号”可以成为盗窃罪的犯罪对象。     

手机用户消费群体弱势地位及法律保护

手机作为网络终端设备,具备了网络终端的一切基本特征。当我们把无线网络中的手机作为独立的研究对象进行考察时,就会发现,无线网络终端用户是最具有典型意义的弱势群体。文章分析了网络电信服务中消费者弱势地位加剧的原因,并对网络环境下完善消费者权益保护的对策进行了有益的探究。     

手机短信息诈骗犯罪的手段、成因、特点及防范

手机短信息诈骗犯罪的主要手段有 :中奖引诱 ,销售廉价走私商品 ,有偿提供六合彩特码 ,征婚骗局 ,结交“Q友” ,办理证件。手机短信息诈骗犯罪的特点 :犯罪手法具有新颖性、隐蔽性、欺骗性 ;犯罪主体具有团伙性。手机短信息诈骗犯罪的防范对策 :大力开展防范宣传 ,提高人们的防范意识 ;加快立法进程 ,完善法制 ;电信部门应加强管理 ,推进改革 ;规范银行管理 ,严格执行规定 ;公安机关力争取证调查透彻 ,全面查处案件     

Recovery of single source DNA profiles from mixtures by direct single cell subsampling and simplified micromanipulation

Deconvolution of forensic DNA mixtures into their individual component DNA (geno)types is of great investigative value, though often complex and difficult. Two-person mixtures comprising a major and minor contributor are often easily interpreted although, when the DNA ratio of the two individuals is approximately equal (~1:1), deconvolution and interpretation becomes much more difficult. To address this issue, a physical separation of individual-, two- or three- cell subsamples prior to autosomal STR analysis was performed using a simplified micromanipulation technique paired with a decreased reaction volume and increased cycle number PCR. Using this method, single and multiple buccal epithelial cells were collected from a 1:1 two-person mixture (i.e. from individual 'A' and 'B') and directly amplified, omitting standard DNA extraction and purification steps. Single cell subsamples resulted in partial single-source profiles for both contributors while, in accordance with expectations of a quasi-binomial sampling schema, two- and three-cell subsamples resulted in single source informative partial profiles of individual A and individual B as well as complete consensus profiles, and equally mixed 1:1 (2-cell subsamples) and 2:1 (3-cell subsamples) admixed profiles of individual A and B. This proof-of-concept approach shows promise in permitting the DNA deconvolution of mixed samples where the individual contributors are present in similar amounts that would otherwise be difficult to interpret, resulting in an increase in evidentiary value. The subsampling approach can be readily investigated for DNA casework applications without additional investment in costly, new equipment, requiring only a stereo microscope and a tungsten needle.     

手机短信诈骗犯罪的预防与控制——从法社会学的视角思考

犯罪是一种复杂、流变的社会现象。随着社会新兴领域研究的不断拓展,科学技术的大踏步前进,犯罪中的高科技、高技能含量正日益扩大,手机短信诈骗便是在时代发展过程中出现的一种新型的诈骗犯罪形式。只有认真研究其特点及发展规律,才能因案施策,迅速侦破此类犯罪案件,并以此把握犯罪发展的轨迹,做好防控和打击工作。     

新藤黄酸对人脐静脉内皮细胞凋亡的影响

目的 探讨新藤黄酸对人脐静脉内皮细胞（human umbilical vein endothelial cells,HUVECs）增殖和凋亡的影响。方法 用不同浓度的新藤黄酸培养细胞24、48 h后,采用MTT法观察新藤黄酸对细胞生长的抑制作用;倒置显微镜下观察HUVECs细胞形态变化;通过DAPI染色后倒置荧光显微镜观察新藤黄酸对细胞形态学的影响;通过Annexin V-FITC/PI双染及流式细胞术检测新藤黄酸对HUVECs细胞凋亡率的影响;Western blot检测新藤黄酸对HUVECs中凋亡相关蛋白Caspase-3的表达变化。结果 MTT检测结果显示新藤黄酸能够明显抑制HUVECs的增殖,并呈时效及量效关系;荧光显微镜观察结果显示,新藤黄酸作用HUVECs后出现大量凋亡细胞;流式细胞术结果显示,与空白对照组相比,随着新藤黄酸浓度的增加,细胞凋亡率明显增加;Western blot检测结果表明Caspase-3蛋白表达水平显著增加。结论 新藤黄酸对HUVECs有明显的抑制作用,其作用机制可能是通过诱导细胞凋亡实现的。     

基于网络药理和细胞实验探索芪玉三龙方治疗非小细胞肺癌的机制

目的 采用网络药理学和细胞实验探究芪玉三龙方治疗非小细胞肺癌的潜在作用机制。方法 利用中药系统药理学数据库与分析平台和中医药整合数据库检索芪玉三龙方成分筛选靶点,通过美国肿瘤基因组图谱数据库获得肺癌靶点基因。构建蛋白相互作用网络,并采用基因本体数据库和京都基因和基因组百科全书数据库进行富集分析。对核心靶蛋白与化合物进行分子对接分析,并以A549细胞进行实验验证。结果 芪玉三龙方对于非小细胞肺癌的潜在有效靶点162个,蛋白相互作用网络分析得到核心靶点基因20个,主要的生物学过程为对缺氧的反应、MAPK级联、炎症反应,主要的功能通路为钙信号通路、TNF信号通路、IL-17信号通路、细胞周期。分子对接结果表明,MMP9-槲皮素、PPARG-异鼠李素、PTGS2-刺芒柄花素、JUN-刺芒柄花素之间存在有效的结合亲和力。在A549细胞实验中,PCR和Western blot分析结果表明,芪玉三龙方含药血清能够促进PPAR-γ mRNA和蛋白表达（P＜0.05）,抑制c-JUN、COX-2、MMP-9 mRNA和蛋白表达（P＜0.05）。结论 芪玉三龙方通过影响A549肺癌细胞的凋亡、侵袭和肿瘤血管生成及炎症进程达到干预肺癌的作用。     

Investigating the uses of mobile phone evidence in China criminal proceedings

Data from mobile phones are regularly used in the investigation of crime and court proceedings. Previously published research has primarily addressed technical issues or provided operational manuals for using forensic science evidence, rather than analysing human factors and the implementation of forensic tools in investigation settings. Moreover, previous research has focused almost entirely on western countries, and there is a dearth of research into the uses of forensic evidence in China. In this study, a review was carried out of court sentencing documents referring to mobile phone evidence in China over the period 2013–2018. Automated content analysis was used to identify the specific evidence types utilised and the sentencing outcome for each case. Results show that mobile phone evidence was used in 3.3% of criminal proceedings. Among various data types mentioned in criminal proceedings, call records sustained as the most frequently used type of data. After which, instant messaging tools (e.g. WeChat) are an increasing proportion of all mobile phone evidence, from 1% in 2015 to 25% in 2018. For cases that utilised mobile phone data, the analysis of instant messaging and online transaction tools is routine, with little variation in the use of each application (WeChat, Alipay, QQ) for investigations of different types of crime. However, in the majority of criminal cases, mobile phone data function as subsidiary evidence and posed limited impacts on verdict reached. The current findings indicate that a large amount of mobile phone evidence was transformed into other evidence formats or filtered out directly before court proceedings.