Diabetes mellitus and hypopituitarism

A 38-year-old diabetic woman developed hyponatraemia and fatal non-ketotic coma after elective cholecystectomy. At the autopsy, it was revealed that the immediate cause of death was cerebral oedema with secondary pontine haemorrhage. The cerebral oedema was associated with severe hyponatraemia and atrophy of the endocrine organs, including the adrenal glands. Biochemical analysis of serum taken immediately before death indicated that the primary defect was pituitary insufficiency, a recognised but rare complication of diabetes.     

Nixon and the Jews

ABSTRACT

In public the 37th President of the United States did not express hostility or disparagement, or show any signs of religious prejudice towards Jews. But inside the White House, Richard M. Nixon's remarks were often scurrilous. His antisemitism was not casual; it was close to compulsive. And it could be coupled with other seething grievances, for example, towards liberals, radicals, the media, Blacks and Italian-Americans. Yet Nixon controlled his antisemitism. It had no adverse effect on Jewish life, either at home or abroad. The malice that he nurtured remained unmobilized. Apart from a few limited personnel instances (mostly but not completely ignored by Nixon's underlings), it is impossible to connect private resentment to public policy, probably because the barriers to the expression of antisemitism in the United States have been so high. The ugliness of his utterances in the Oval Office revealed his character, but did not extend outward to shape the processes of governance. A disconnect can therefore be discerned between what he felt and how he acted. Most American Jews voted for Nixon's Democratic opponents in 1968 and 1972. But even Jews who voted against him, even those who loathed him, have often acknowledged that Nixon's policies fortified the security of Israel; and he was proud of his support for the Jewish state during the Yom Kippur War. What betrayed Nixon, and what forced him to resign the presidency, was his decision to instal a secret taping system in the Oval Office. When the tapes were played in 1974, he showed himself to be conspiring to obstruct justice. In subsequent years, further exposure of the tapes revealed the extent and intensity of Nixon's antipathy to Jews. The expletives that had to be deleted did much to besmirch the dignity of the office. But such was the stigma the political culture attached to antisemitism that, had his bigotry become public before 1968, Nixon's career would have been over.     

Magnitude and durability of electoral change: Identifying critical elections in the U.S. Congress 1854–2010

The two hallmarks of a critical election and, hence, of a critical realignment are the magnitude of the observed change and the durability of that change. In addition to offering a new approach to measuring durable change in national party dominance, and providing a non-parametric criterion to identify unusual changes in seat/vote shares, we provide fresh insights via a unifying statistical approach that reflects both of these factors simultaneously. Furthermore, we assess the robustness of critical election determinations in two ways. First, we compare the magnitude of inter-election shifts with both average volatility over the entire time period and volatility relative to a particular time period. Second, as an alternative to the usual perspective, we consider critical elections not as a one-time cataclysm, but rather as a pair (or perhaps even triple) of consecutive substantial shifts, generated by the same underlying factors. Overall, we distinguish six elections that marginally or provisionally meet our criteria to be critical elections. But focusing on pairs of elections, 1858–60 and 1930–32 stand out as critical among all elections since the 1850s.     

野田内阁加入TPP的战略意图探析

TPP是一种旨在实现贸易、投资及人员往来等全面自由化的高水平自由贸易协定。野田内阁意图通过TPP提升日本企业的国际竞争力,推动国内农业的结构性改革,重振日本经济;在对外关系上,则欲借此修复巩固日美同盟,配合美国牵制中国的战略布局,并在未来亚太经济一体化的进程中占据有利位置。基于上述战略意图,尽管遭到日本国内长期依赖财政补贴及贸易保护的农业部门和希望继续维持现有医疗保障体系的医师会等团体的坚决反对,以致日本面临政治分裂的风险,野田仍作出了参加TPP谈判的政治决断。     

美国证据排除规则的衰变及其启示——以Herring v. United States案为主线的考察

2009年1月的Herring v.United States案判决是近年来美国联邦最高法院关于证据排除规则方面影响最大的判决,它确立了＂过失行为所得非法证据不适用证据排除＂的新规则。该判决以其不同以往任何案例的特殊性引发了关于证据排除的存在必要性、适用范围、审查模式等一系列问题的理论探讨和实务争议。以该判决前后美国联邦最高法院的态度转变和学界回应为鉴,我国证据排除规则的确立应定位于阻吓违法行为,以过错原则为判断标准,并配合职务监督方式施行。     

Comparison of two methods for isolating DNA from human skeletal remains for STR analysis

Abstract: The quality and efficiency of a standard organic DNA isolation method and a silica‐based method using the QIAGEN Blood Maxi Kit were compared to obtain human DNA and short tandem repeats (STRs) profiles from 39 exhumed bone samples for paternity testing. DNA samples were quantified by real‐time PCR, and STR profiles were obtained using the AmpFlSTR^® Identifiler^® PCR amplification kit. Overall, the silica‐based method recovered less DNA ranging from 0 to 147.7 ng/g (average 7.57 ng/g, median = 1.3 ng/g) than did the organic method ranging from 0 to 605 ng/g (average 44.27 ng/g, median = 5.8 ng/g). Complete profiles (16/16 loci tested) were obtained from 37/39 samples (95%) using the organic method and from 9/39 samples (23%) with the silica‐based method. Compared with a standard organic DNA isolation method, our results indicate that the published silica‐based method does not improve neither the quality nor the quantity of DNA for STR profiling.     

Fournier Gangrene and Unexpected Death

Abstract: Fournier gangrene represents a rare but progressive perineal infection that may result in rapid death. A 70‐year‐old man with poorly controlled diabetes mellitus and alcohol abuse is reported who was found unexpectedly dead. He had last been contacted the night before his death. At autopsy, the most striking finding was deep necrotic ulceration of the scrotum with exposure of underlying deep muscles and testicles, with blood cultures positive for Escherichia coli. Death was, therefore, attributed to necrotic ulceration/gangrene of the perineum (Fournier gangrene) that was due to E. coli sepsis with underlying contributing factors of diabetes mellitus and alcoholism. In addition there was morbid obesity (body mass index 46.9), cirrhosis of the liver, and marked focal coronary artery atherosclerosis with significant cardiomegaly. Fournier gangrene may be an extremely aggressive condition that can result in rapid death, as was demonstrated by the rapid progression in the reported case.     

WTO中的公共道德例外条款分析

多边贸易协定一个重要目的就是消除贸易壁垒,实现贸易自由化。但是有时过度地追求贸易自由可能会给一国的公共道德造成威胁。因此,在多边贸易协定中往往内含了一些可以豁免缔约方缔约义务的例外条款。缔约方为了保护本国的公共道德,可以援引这些例外条款来对抗其他缔约方的指控。在WTO中,公共道德例外主要体现在GATT第20条﹙a﹚和GATS第14条﹙a﹚。另外,在《与贸易有关的知识产权协定》第27条第2款和《政府采购协定》第23条第2款中也规定了这种例外。     

美国国家安全委员会变迁探析

美国建立了世界上第一个国家安全委员会,历经67年世势风云的洗礼,美国国家安全委员会已成为美国处理所有国际事务的中心,作为美国国家安全事务的咨询与协调机构,它在美国国家安全决策过程乃至世界外交局势的演变中都持续发挥着重要的影响力。历经各任领导者对其地位与角色的不同定位,美国国家安全委员会的职能、制度、运行及决策程序在不断修改与调整中走向稳定与成熟。其机构和人员的设置既审时度势、灵活多样、顺应时代变化,又逐渐探索确立了富有特色的部际协调机制,将各法定成员、法定顾问、国家安全事务助理以及非法定成员有效地组织起来,通过形式各异的正式程序、非正式程序以及秘密程序的分析、评估与协调会议,为总统的国家安全事务决策提供必不可少的支持。美国国家安全委员会变迁与改革的每一步都伴随着法律及行政法令的颁行与修订,授权与监督,体现了法制先行的特点。美国国家安全委员会戏剧性的发展历程中积累的经验与教训,为中国建立不久的中央国家安全委员会提供了借鉴。     

3D打印治安管理对策研究

3D打印技术如今已受到了社会各界广泛的关注,有着良好的发展前景。然而其本身也具有着一定的治安隐患,如危险物品泛滥、特殊物品复制等。对于3D打印技术,需要进行系统的风险评估,并通过完善机制的构建进行人为控制,以保证其健康发展。这一机制的构建,除了应运用较多的高科技手段外,也应当在管理规范层面做到有序、协调。