人民民主专政理论的哲学分析及当代启示

人民民主专政理论是毛泽东思想的重要组成部分,包含着丰富的哲学思想。关于这一理论的哲学分析,对当前中国特色社会主义建设的启示是:党必须推动中国经济社会的全面发展,必须始终把发展作为党执政兴国的第一要务,必须始终坚持以人为本的执政理念,必须用发展着的马克思主义指导中国新的实践。     

师专学生心理健康状况的调查分析及对策

对1986名师范专科学校的新生的心理健康状况调查表明,有12.34%的学生存在不同程度的心理症状和心理问题,有50.14%的学生存在人际关系不协调、新环境不适应等问题。造成大学生心理健康状况欠佳的原因是多方面的,学校有必要进一步加强学生的心理卫生教育。     

Science Parks’ tenants versus out-of-Park firms: who innovates more? A duration model

We study the successfulness of Science Parks (SPs) as seedbeds of innovation. We investigate whether SPs enhance the innovative output of their tenants and if tenants outperform comparable outside-SPs firms. We rely on original matching datasets regarding in- and out-SP Finnish firms and their patenting activity over 1970–2002. We estimate and compare the ‘before-versus-after’ hazard rates of patenting of both samples. The results suggest that, given the existence of a common tendency to slow down the pace at which all firms patent during their life cycle, Park tenants exhibit a comparatively better performance. Results are robust to various model specifications and to Wald tests performed over the pooled samples.

Identification of acepromazine in hair: an illustration of the difficulties encountered in investigating drug-facilitated crimes

After a drug-facilitated sexual assault (DFSA), a woman was found in a drowsy state at home. She remembered having drunk an unknown beverage by the accused. Blood samples (collected 8 hours after the DFSA), two glasses, and a teaspoon seized by the police were analyzed. Acepromazine, a phenothiazine tranquilizer used in human and veterinary medicine, was detected in the residue of one of the glasses. In spite of acepromazine absence in the victim's blood, the possible use of acepromazine in the DFSA was reported to the police. Two weeks later, a suspect admitted having orally administered acepromazine to the victim. Using a liquid chromatography-tandem mass spectrometry method, this compound was subsequently detected (31 pg/mg) in a sample of the victim's hair collected a month and a half after the DFSA. A potential short elimination half-life in humans and/or the well-known in vitro degradation of acepromazine could explain the negative blood result. DFSA toxicological investigations are challenging and can be complicated when a rather unusual substance is concerned. In particular, special care should be taken when interpreting the results, taking into account elimination and/or instability data, when available.     

A real-time multiplex SNP melting assay to discriminate individuals

A method that quickly and inexpensively differentiates crime scene samples from multiple donors would expedite casework analysis by allowing the selection of probative items requiring comprehensive testing. This new method need not be perfectly definitive nor give a complete 13 locus short tandem repeat (STR) profile; it simply must be able to differentiate between most victim and suspect samples. We describe the development of multiplex, single nucleotide polymorphism (SNP), fluorescence resonance energy transfer-based real-time polymerase chain reaction (PCR) assays to fulfill this need. Dual probes, one fluorescently labeled and the other labeled with a quencher, are monitored during a melt analysis to reveal an increase in fluorescence, which allows the assessment of the two SNP alleles. Two alternate 6-plex assays (with and without gender determination) have been developed for the six-color RG6000 real-time instrument (Corbett Robotics, Inc.) and one seven SNP plus gender assay (performed as two 4-plex assays, one with gender the other without) have been developed for use in four/five color real-time instruments. This technique can discriminate between 95% and 99% of samples from different individuals. This assay is fast (approximately 2 h), much less expensive than STR analysis, and uses a real-time PCR instrument which is found in most forensic and molecular biology labs.     

大鼠弥漫性轴索损伤后NGF表达

目的研究大鼠弥漫性轴索损伤后神经生长因子（NGF）表达的时间变化规律及意义。方法采用SD雄性大鼠复制弥漫性轴索损伤（DAI）模型,分别于伤后1、3、6、12、24、48h和3、7d取脑组织,应用免疫组织化学法对DAI后不同时间段大脑皮层、丘脑、小脑和海马部位NGF的表达变化进行观察并与正常组、假手术组对照。结果正常及假手术组大鼠大脑皮层、丘脑、小脑、海马均有少量NGF的表达。打击后1hNGF表达增强,12h达高峰,3d开始下降,7d降至正常。结论NGF参与弥漫性轴索损伤后的修复：NGF的时序性变化有望成为法医学脑损伤时间推断的客观指标。     

Classification and individualization of black ballpoint pen inks using principal component analysis of UV-vis absorption spectra

The technique of principal component analysis has been applied to the UV-vis spectra of inks obtained from a wide range of black ballpoint pens available in the UK market. Both the pen ink and material extracted from the ink line on paper have been examined. Here, principal component analysis characterised each spectrum within a group through the numerical loadings attached to the first few principal components. Analysis of the spectra from multiple measurements on the same brand of pen showed excellent reproducibility and clear discrimination between inks that was supported by statistical analysis. Indeed it was possible to discriminate between the pen ink and the ink line from all brands examined in this way, suggesting that the solvent extraction process may have an influence on these results. For the complete set of 25 pens, interpretation of the loadings for the first few principal components showed that both the pen inks and the extracted ink lines may be classified in an objective manner and in agreement with the results of parallel thin layer chromatography studies. Within each class almost all inks could be individualised. Further work has shown that principal component analysis may be used to identify a particular ink from a database of reference UV-vis spectra and a strategy for developing this approach is suggested.     

A Bayesian approach to estimate skeletal age-at-death utilizing dental wear

In the forensic context, teeth are often recovered in mass disasters, armed conflicts, and mass graves associated with human rights violations. Therefore, for victim identification, techniques utilizing the dentition to estimate the first parameters of identity (e.g., age) can be critical. This analysis was undertaken to apply a Bayesian statistical method, transition analysis, based on the Gompertz-Makeham (GM) hazard model, to estimate individual ages-at-death for Balkan populations utilizing dental wear. Dental wear phases were scored following Smith's eight-phase ordinal scoring method and chart. To estimate age, probability density functions for the posterior distributions of age for each tooth phase are calculated. Transition analysis was utilized to generate a mean age-of-transition from one dental wear phase to the next. The age estimates are based on the calculated age distribution from the GM hazard analysis and the ages-of-transition. To estimate the age-at-death for an individual, the highest posterior density region for each phase is calculated. By using a Bayesian statistical approach to estimate age, the population's age distribution is taken into account. Therefore, the age estimates are reliable for the Balkan populations, regardless of population or sex differences. The results showed that a vast amount of interpersonal variation in dental wear exists within the current sample and that this method may be most useful for classifying unknown individuals into broad age cohorts rather than small age ranges.     

Assessing the (eco)macroeconomic performance index of India: A data envelopment analysis approach

The prime objective of this article is to construct a robust macroeconomic performance (MEP) index of the Indian economy using the data envelopment analysis (DEA) approach. Seven major macro indicators, namely, economic growth, employment rate, terms of trade, inflation rate, fiscal deficit, pollution, and climate change are used to compute MEP and Eco‐MEP indices of the Indian economy from 1980–1981 to 2018–2019. Overall, both the MEP and Eco‐MEP index scores have quite similar best performing years worst performing years, and have also captured the major events that affected adversely the Indian economy during the past decades. The trend in the overall performance of the Indian economy was better in the 1980s and the 1990s but has deteriorated since 2000. The autoregressive distributed lag bounds testing approaches to cointegration methods are used to test the robustness/utility of these indices. The estimated results show that MEP and Eco‐MEP have a positive impact on private investment, foreign investment inflows, foreign direct investment, and a negative effect on the current account deficit. Hence, the suggested composite MEP index is stable, robust and truly captures the economic performance of India. The constructed MEP composite index may be used by foreign investors, rating agencies, private investors, and policymakers for their planning and decision‐making processes.