Potential forensic application of closely linked autosomal STR haplotype in complex kinship testing

It has been noticed that the most commonly used commercial STR kits and mtDNA may not be able to solve some special kinship cases, such as alleged aunt, uncle, niece, nephew or half-siblings. Due to its unique hereditary pattern, the haplotype of genetic markers could be a solution of these questioned family relationships. In this study, we investigated the genetic features of an autosomal STR cluster by employing confirmed family samples. To evaluate the forensic practical value of autosomal STR haplotype, 5 closely linked STR loci, D1S2127-D1S2138-D1S3460-D1S1643-D1S518, which were arranged in about 2 cM region (from 186.29 cM to 188.02 cM; 1 cM represents 1% average recombination between two loci) on chromosome one, were selected to compose haplotype. Genotyping of 60 samples from 8 trios (father–mother–children), 8 duos (father or mother–children), and 4 three-generation pedigrees were performed using PAGE. Haplotypes were identified in the child by determining alleles for all 5 loci transmitted from each parent. Total 73 haplotypes were detected in all samples and 34 haplotypes were observed to be passed down as a whole and was corresponding with the inherited characteristics of haplotype. In all family members, 34 unrelated individuals contributed 65 haplotypes, of which 62 haplotypes appeared only once and the rest 3 haplotypes appeared twice. No recombination was observed in 4 three-generation pedigrees. In conclusion, the haplotype consisting of 5 closely linked autosomal STRs could pass down steadily as a whole. The family specificity of most haplotypes may provide a unique advantage in forensic complex kinship testing.     

Comment on Carl Abbott's “The Portland region: Where city and suburbs talk to each other—and often agree”

Abstract

The Portland, OR, area's urban growth boundary is an idea whose benefits to the region may depend on a willingness to expand the boundary occasionally. The parable contained in this comment suggests that the declared unwillingness to expand the urban growth boundary could have contributed to Portland's recent sudden increase in housing prices. It further suggests that an inflexible attitude toward the boundary could cause long‐run losses in employment in the Portland region, with few if any offsetting environmental benefits. Other regions should be aware of the potential drawbacks of installing such a boundary.     

Some realities about sprawl and urban decline

Abstract

Many urban analysts believe suburban sprawl has become an important issue because it helps generate two types of problems: growth‐related difficulties like rising traffic congestion, and high concentrations of poor minority households in core‐area neighborhoods. However, a careful regression analysis of measures of both sprawl and urban decline shows no statistically significant relation between these two conditions.

The basic nature of the American urban development process would cause core‐area poverty concentrations even if sprawl were replaced by more compact growth forms. But sprawl does aggravate growth‐related problems. Those problems could be attacked through either alternative overall growth strategies—such as high‐density, tightly bounded growth—or specific anti‐sprawl tactics, such as regional tax‐base sharing and regional coordination of land uses. But no feasible policies are likely either to alleviate traffic congestion much or cause most American regions to abandon sprawl.     

Comment on John T. Metzger's “planned abandonment: The neighborhood life‐cycle theory and national urban policy”

Abstract

I take strong exception to the idea that theories of neighborhood change, in and of themselves, caused the decline of inner cities. Rather, the demographic, social, and economic forces that existed in the postwar years caused some inner‐city neighborhoods to decline. The replacement of working‐class and middle‐income households by households with much lower incomes, on average, was the single biggest cause of neighborhood decline. Metzger ignores this fact as an alternative explanation for why some neighborhoods declined. It is highly implausible that my theories and those of other urban experts had such a strong impact on the public policy, building, and finance communities. Because people were responding to real conditions, it is likely that the same events would have occurred even if my model of neighborhood change had never been developed.     

New Urbanism and Selection Bias in the Formation of Social Capital

Over the past several decades, there has been a decline in social capital in American communities. New urbanism has been proposed as a tool to reverse some of this decline. This study seeks to understand the potential benefits of new urbanism in terms of social capital. Differences in social capital between a new urbanist subdivision (NUS) and a standard suburban subdivision (SSS) are compared. The findings of this study suggest that residents of NUSs have more social capital than residents of SSSs. However, many of the differences between the two communities disappeared when a social bias control was added to the model.     

Administrative Capacity Building of Public Administrations Under the European Financial Assistance

From a European perspective as referring to EU member states, which are receiving European financial assistance, the idea of assessment of the countries＇ administrative capacity represents a priority and an issue of concern not only for the new member countries but also for the all the member countries. Based on its functions, public institutions should perform an evaluation or measure their administrative and organizational capacity performance when significant changes occur, in order to facilitate the necessary improvements for their organizational and administrative capacity. Following these considerations, after studying the literature concepts about the administrative capacity and based upon an empirical research, this article aims： （1） to classify the European countries （EU27） according to their administrative capacity, based on some relevant identified indicators as following the European Commissions＇ reports from the official websites; and （2） to identify and analyze the influence and effects that strategic management and project management have on the administrative capacity of Romanian public administration using a survey which analyses the performance of the Romanian public administration.