Impact of Myocardial Infarction and Abnormalities of Cardiac Conduction System on Sudden Cardiac DeathCSCD

Sudden cardiac death (SCD), most commonly seen in coronary heart disease, is a kind of sudden death caused by series of cardiac parameters, which usually combines with myocardial infarction. However, some SCDs (including early myocardial infarction) happen suddenly and cause death in a very short time. In these circumstances, typical morphological changes are lack in macroscopic or microscopic fields, which make such SCDs become the emphasis and difficulty in the present research. SCD caused by myocardial infarction and abnormalities of cardiac conduction system (CCS) is related to atherosclerosis of coronary artery closely. This paper reviews cardiac dysfunction caused by myocardial infarction and diseases of CCS from morphology and molecular biology, and explores potential relationship between them. This paper aims to provide clues to the mechanism of myocardial infarction related sudden death and possible assistance for forensic diagnosis of SCD. © 2017 by the Editorial Department of Journal of Forensic Medicine.     

Full Sibling Identification by IBS Scoring Method and Establishment of the Query Table of Its Critical ValueCSCD

Objective: To establish a query table of IBS critical value and identification power for the detection systems with different numbers of STR loci under different false judgment standards. Methods: Samples of 267 pairs of full siblings and 360 pairs of unrelated individuals were collected and 19 autosomal STR loci were genotyped by Goldeneye™ 20A system. The full siblings were determined using IBS scoring method according to the 'Regulation for biological full sibling testing'. The critical values and identification power for the detection systems with different numbers of STR loci under different false judgment standards were calculated by theoretical methods. Results: According to the formal IBS scoring criteria, the identification power of full siblings and unrelated individuals was 0.764 0 and the rate of false judgment was 0. The results of theoretical calculation were consistent with that of sample observation. The query table of IBS critical value for identification of full sibling detection systems with different numbers of STR loci was successfully established. Conclusion: The IBS scoring method defined by the regulation has high detection efficiency and low false judgment rate, which provides a relatively conservative result. The query table of IBS critical value for identification of full sibling detection systems with different numbers of STR loci provides an important reference data for the result judgment of full sibling testing and owns a considerable practical value. © 2017 by the Editorial Department of Journal of Forensic Medicine.     

Analysis on the Injury Mechanism and Characteristics of Ox HornCSCD

Objective: To study the morphological characteristics of the injury caused by ox horn on human body and its injury mechanism, and to discuss the rules and characteristics of injury by ox horn and provide forensic evidences for identification of such cases. Methods: The comparative analysis of position and morphological characteristics were performed by summarizing the data of 100 victims gored by ox accepted by Heilongjiang agricultural areas public security bureau during 2004-2014. Results: The specific injuries only could be found at the contact positions such as thorax and abdomen, lower back and limbs of the victims gored by ox horn. Most of the skin wounds had the characteristics of sharp injuries, the bar-type injury by club which called "rail way bruise" was an obvious characteristic appeared on the soft tissue. Conclusion: Ox horn can cause non-specific injuries on thorax and abdomen, lower back and limbs of human body, which are similar with the characteristics of sharp injury and injury by club. Careful analyzation and identification should be performed on such injury in daily work. © 2017 by the Editorial Department of Journal of Forensic Medicine.     

Correlation between Genetic Variants and Polymorphism of Caveolin and Sudden Unexplained DeathCSCD

Objective: To explore the genetic variation sites of caveolin (CAV) and their correlation with sudden unexplained death (SUD). Methods: The blood samples were collected from SUD group (71 cases), coronary artery disease (CAD) group (62 cases) and control group (60 cases), respectively. The genome DNA were extracted and sequencing was performed directly by amplifying gene coding region and exonintron splicing region of CAV1 and CAV3 using PCR. The type of heritable variation of CVA was confirmed and statistical analysis was performed. Results: A total of 4 variation sites that maybe significative were identified in SUD group, and two were newfound which were CAV1:c.45C>T (T15T) and G4V7:C.512G>A (R171H), and two were SNP loci which were CAVl:c.246C>T (rs35242077) and CAV3:C.990T (rsl008642) and had significant difference (P<0.05) in allele and genotype frequencies between SUD and control groups. Forementioned variation sites were not found in CAD group. Conclusion: The variants of CAV1 and CAV3 may be correlated with a part of SUD group. © 2017 by the Editorial Department of Journal of Forensic Medicine.     

Forensic analysis of Telegram Messenger for Windows Phone

This article presents a forensic analysis methodology for obtaining the digital evidence generated by one of today's many instant messaging applications, namely “Telegram Messenger” for “Windows Phone”, paying particular attention to the digital forensic artifacts produced. The paper provides an overview of this forensic analysis, while focusing particularly on how the information is structured and the user, chat and conversation data generated by the application are organised, with the goal of extracting related data from the information. The application has several other features (e.g. games, bots, stickers) besides those of an instant messaging application (e.g. messages, images, videos, files). It is therefore necessary to decode and interpret the information, which may relate to criminal offences, and establish the relation of different types of user, chat and conversation.     

Historical Trends in Graduate Research and Training of Diplomates of the American Board of Forensic Anthropology

The history of forensic anthropology has been documented by numerous scholars. These contributions have described the work of early pioneers in the field and have described important milestones, such as the founding of the Physical Anthropology Section of the American Academy of Forensic Sciences (AAFS) in 1972 and the American Board of Forensic Anthropology (ABFA) in 1977. This paper contributes to the growing literature on the history of forensic anthropology by documenting the academic training of all individuals who have been granted diplomate status by the ABFA (n = 115). Doctoral dissertation titles were queried to discern broad patterns of research foci. A total of 39 doctoral granting institutions have trained diplomates and 77.3% of board‐certified forensic anthropologists wrote dissertations involving skeletal biology, bioarchaeology, or forensic anthropology. Board‐certified forensic anthropologists are a broadly trained group of professionals with far‐reaching anthropological interests and expertise.     

情杀酿悲剧之案例分析

情杀往往发生于传统观念与现代观念冲突,当今年轻人道德观念日渐淡薄,夫妻间忠诚难以坚守。本案通过法医病理学及DNA检测,发现死者双方尸体上损伤属法医病理学典型的自杀和他杀特征。男方割腕后,采用暴力手段将女方致死进而自杀身亡。这种轻视他人和自己生命的做法便导致悲剧的发生。     

情杀酿悲剧之案例分析

情杀往往发生于传统观念与现代观念冲突,当今年轻人道德观念日渐淡薄,夫妻间忠诚难以坚守。本案通过法医病理学及DNA检测,发现死者双方尸体上损伤属法医病理学典型的自杀和他杀特征。男方割腕后,采用暴力手段将女方致死进而自杀身亡。这种轻视他人和自己生命的做法便导致悲剧的发生。     

A study on the forensic mechanisms of VoIP attacks: Analysis and digital evidence

This paper discusses the use of communication technology to commit crimes, including crime facts and crime techniques. The analysis focuses on the security of voice over Internet protocol (VoIP), a prevention method against VoIP call attack and the attention points for setting up an Internet phone. The importance of digital evidence and digital forensics are emphasised. This paper provides the VoIP digital evidence forensics standard operating procedures (DEFSOP) to help police organisations and establishes an experimental platform to simulate phone calls, hacker attacks and forensic data. Finally, this paper provides a general discussion of a digital evidence strategy that includes VoIP for crime investigators who are interested in digital evidence forensics.     

An analysis of single and multi-copy methods for DNA quantitation by real-time polymerase chain reaction

The goal of this paper was to examine and compare two different commercially available approaches to the determination of the relative quantities of autosomal and Y chromosomal DNA using real-time PCR. One, Quantifiler^® Duo, utilizes a TaqMan^® assay with single copy probes for both autosomal human and Y quantification. The other method, Plexor HY^® utilizes a primer quenching assay with multi-copy probes for its quantification of autosomal human and Y chromosomal DNA. To test these approaches we have utilized the NIST Human DNA Quantitation Standard Reference Material 2372, a set of three different NIST human DNA quantification standards, to examine the precision, accuracy and sensitivity of the real-time PCR assays. We also examined data from both systems utilizing casework samples. The results show that both systems produced linear estimates for DNA quantity over a broad range of input DNA. However we did observe some apparent copy number effects when comparing the three different NIST standards which we attributed to issues with sequence variations in the different standards. Overall, the single copy approach provided better accuracy while the multi-copy approach produced better sensitivity. Thus the choice of which system to use should depend upon the goals of the user.