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921.
922.
大鼠心肌缺血后SERCA和PLB基因表达变化的观察 总被引:1,自引:0,他引:1
目的观察大鼠心肌缺血后,肌浆网钙调节蛋白SERCA和PLB基因表达水平变化,探讨其在早期心肌缺血诊断上的应用价值。方法25只大鼠随机分为正常对照组、缺血5、10、15min及缺血性猝死组,建立大鼠急性心肌缺血模型;利用荧光标记逆转录聚合酶链反应技术(RT—PCR)检测不同时间大鼠心肌缺血后,SERCA和PLB的基因表达变化,并与缺血性猝死组相比较。结果心肌缺血5min即可检测到SERCA和PLBmRNA表达相对下降,且随着缺血时间的延长,呈逐渐下降趋势,心肌缺血组与缺血性猝死组表达存在显著性差异。结论大鼠心肌缺血后SERCA和PLB基因表达变化呈一定规律性。对早期心肌缺血的诊断具有法医学意义。 相似文献
923.
Alexandra Szőke 《Citizenship Studies》2015,19(6-7):734-750
The paper discusses the effects of the ‘public work programme’ on social citizenship in remote rural localities in Hungary, where it has developed into an extreme form of workfare in lack of other employment options. Drawing on extensive empirical material from two rural localities, the paper shows that, due to decentralisation, large variations exist in the ways the programme is implemented locally. The practices and approach of local officials, who as key welfare workers in a highly decentralised state primarily determine its local implementation, are strongly linked to local social relations, as well as dominant notions of deservingness/undeservingness on which local claims and negotiations of belonging are based. The study concludes that, whilst the programme fails to address, and even upholds, structural inequalities, the ways in which the programme is organised can, nevertheless, fundamentally affect both the material welfare and the locally constituted social citizenship of its participants. 相似文献
924.
N. Siklodi 《Citizenship Studies》2015,19(6-7):820-835
Globalisation has begun to transform the processes through which citizens are differentiated and non-citizens are excluded. This article provides an in-depth qualitative interrogation of these processes of differentiation and exclusion, and argues that the transformation in these processes compels us to reconsider the conceptual dichotomy of passive/active citizens along the stayers/mobiles distinction. This transformation is most apparent in Europe, with the introduction of European Union (EU) citizenship. The article builds on Bourdieu’s cultural capital in the cosmopolitan context, existing qualitative studies on citizens’ sense of EU identity and citizenship, and illustrative focus group evidence of visiting EU and home students’ perceptions of EU citizenship across three dimensions – identity, rights and participation. The evidence indicates that we can distinguish between four categories of citizens in the EU: passive EU citizens, including two groups of stayers; the potential EU (i) and member state-oriented (ii) citizens, and active EU citizens, including EU-15 (iii) and Central and Eastern European (iv) mobile citizens. These categories reveal that important distinctions are emerging between the perceptions and behaviour of stayers and mobiles as passive/active citizens. 相似文献
925.
Libby McEnhill 《The Political quarterly》2015,86(1):101-109
Parties in coalition governments must address the ‘unity/distinctiveness’ dilemma: how to maintain governing cohesion, while sustaining individual identities. Within the Cameron–Clegg government this is a challenge for both parties, but it is more so for the Liberal Democrats as the junior partner. This paper considers how the Liberal Democrats negotiated this dilemma in relation to ministerial portfolio allocations. While the Liberal Democrat strategy of placing ministers in almost all departments has served the Coalition well in terms of governing unity, it has limited the extent to which they have been able to assert their distinctive contribution to Coalition policy‐making. This is demonstrated through an examination of the Liberal Democrats' influence on Coalition welfare policy. A lack of clear policy contributions is potentially highly damaging to the Liberal Democrats electorally, as it suggests that they have made little substantive contribution to the Coalition beyond propping up their Conservative partners. Accordingly, the paper reflects on lessons for junior partners in future UK coalition governments, suggesting that concentrating ministers within one or two departments may provide a more viable means of carving out a distinctive governing legacy. 相似文献
926.
When the US President's Emergency Plan for AIDS Relief (PEPFAR)-supported Supply Chain Management System (SCMS) programme began working in Ethiopia in 2006, the estimated population of people living with HIV exceeded one million, while only 24,000 were on treatment and only 50 treatment sites were in operation. SCMS and other key partners entered into this context to support the Ethiopian government in significantly strengthening the public health supply chain system, with the aim of increasing the availability and accessibility of pharmaceutical products. The country now has 1,047 treatment sites and is nearing complete treatment coverage. This article discusses how priorities were set among many competing challenges from 2006 until 2014, and how the four-step strategy of build, operate, transfer, and optimise has resulted in a successful partnership. 相似文献
927.
This article demonstrates how donor resources can enable MSM/TG practitioners to exercise agency in diverse ways, which produce collateral benefits for sexuality/gender-diverse communities. By focusing on what Thai MSM/TG practitioners actually do, we illustrate how their practices respond to their own aspirations, not only the demands of donor funding regimes. We position our project as queer in the sense that it interrupts the normative absence of practitioner agency within current “MSM” development literature. We argue that our reading might enable greater recognition and donor support for MSM/TG practitioners who produce collateral benefits through their work. 相似文献
928.
Like many other political actors, the extreme right is currently expanding beyond national borders, and, as with any civil society organization, the Internet is assuming a growing role in achieving this goal. To date, however, this topic is understudied. In this article, aiming to empirically filling this gap, we shall explore the new tactics of the extreme right in Europe and the USA in the context of transnational politics. Namely, we investigate the degree and forms of extreme right transnationalization (in terms of mobilization, issues, targets, action strategies, and organizational contacts) and the potential role of the Internet in these developments. The analysis combines qualitative and quantitative data derived from 54 interviews with representatives of extreme right organizations in six European countries (Austria, France, Germany, Great Britain, Italy, and Spain) and the USA with a formalized Web content analysis of 336 right-wing websites. We will compare different types of right-wing groups which compose the radical right family (from political parties to associations), underlining the main differences and similarities across groups and across countries. 相似文献
929.
Stephen Gilmore 《The Modern law review》2015,78(6):1042-1056
This comment examines Re D (Withdrawal of Parental Responsibility), the first reported Court of Appeal decision on withdrawal of parental responsibility pursuant to section 4(2A) of the Children Act 1989. It demonstrates that the Court overlooked earlier Court of Appeal authority, resulting in tension in the Court's guidance. The comment criticises the Court of Appeal's characterisation of parental responsibility as entirely child‐centred and its uncritical acceptance that the child's welfare is the paramount consideration in applications for withdrawal of parental responsibility. It argues that such an approach may not adequately respect the parent's interests in retaining parental responsibility, especially in the context of an order which is more draconian in effect than a care order. The impact upon applications for removal of parental responsibility of the new presumption of parental involvement, which was implemented shortly after the decision in Re D, is also considered. 相似文献
930.
A record six African states were awarded a national pavilion at the 2013 Venice Biennale, the premier venue for showcasing a nation's contemporary art, from which Africa has historically been excluded. While first-time participant Angola won the top prize, Kenya's pavilion was the target of bafflement and ire. Using a cultural diplomacy framework that integrates the insights of leading scholars, this research makes concrete recommendations for practitioners vis-à-vis a comparative case study of the two pavilions. Analysis and recommendations consider the interests of a variety of stakeholders and offer insights relevant to Africa and other emerging regions. 相似文献