Developing STR databases on structured populations: The native South Siberian population versus the Russian population

Developing a forensic DNA database on a population that consists of local ethnic groups separated by physical and cultural barriers is questionable as it can be genetically subdivided. On the other side, small sizes of ethnic groups, especially in alpine regions where they are sub-structured further into small villages, prevent collecting a large sample from each ethnic group. For such situations, we suggest to obtain both a total population database on allele frequencies across ethnic groups and a list of θ-values between the groups and the total data. We have genotyped 558 individuals from the native population of South Siberia, consisting of nine ethnic groups, at 17 autosomal STR loci of the kit packages AmpFlSTR SGM Plus и AmpFlSTR Profiler Plus. The groups differentiate from each other with average θ-values of around 1.1%, and some reach up to three to four percent at certain loci. There exists between-village differentiation as well. Therefore, a database for the population of South Siberia is composed of data on allele frequencies in the pool of ethnic groups and data on θ-values that indicate variation in allele frequencies across the groups. Comparison to additional data on northeastern Asia (the Chukchi and Koryak) shows that differentiation in allele frequencies among small groups that are separated by large geographic distance can be even greater. In contrast, populations of Russians that live in large cities of the European part of Russia are homogeneous in allele frequencies, despite large geographic distance between them, and thus can be described by a database on allele frequencies alone, without any specific information on θ-values.     

保障流动人口合法权益 促进厦门和谐社会建设

随着厦门市经济发展和社会进步,流动人口劳工总量呈稳步上升之势.虽然厦门市在保障流动人口权益、促进厦门和谐社会建设方面取得了显著成绩,但还存在着一些问题,为此应采取措施,保障流动人口合法权益,促进和谐社会建设.     

Analysis of 124 SNP loci included in HID Ampliseq identity panel in a small population of Rio de Janeiro,Brazil

Implementation of massively parallel sequencing platforms can bring a great contribution to Forensic Genetics field, with a great saving of time and costs, as well as allowing reliable results to be obtained from small or extremely degraded samples. The aim of this work was to analyze 124 SNP loci (90 autosomal and 34 Y-SNP) included in HID-Ion Ampliseq Identity Panel in a small sample from Rio de Janeiro state, Brazil. Samples from 12 non-related individuals were amplified with HID-Ion Ampliseq Identity Panel and sequenced on the Ion Torrent PGM platform (Thermo Fisher Scientific); genotypes were generated with HID SNP Genotyper plugin and forensic parameters were calculated with PowerStats v.12. All samples were successfully genotyped and were used to calculate allele frequencies, homozygosity, heterozygosity, random match probability (RMP) and exclusion power for all 90 autosomal SNP loci. Using the formula proposed by Budowle et al. (1996), only 4 of the 90 loci genotyped (4,4%) showed allele frequencies below the minimum required. It means that although a small set of individuals was used on this study, it may have shown a good perspective of Rio de Janeiro state allele frequencies. Among the 11 male samples analyzed, a prevalence of the haplogroup R1b of Y chromosome was observed, followed by the haplogroups E, Q and J. Such distribution reflects the results demonstrated in other studies for the population of Rio de Janeiro. All results together demonstrate the usefulness and applicability of SNP analysis on Ion Torrent PGM.     

Autosomal microsatellite data from Northwestern Colombia

Allele frequencies and some forensic parameters for 12 autosomal microsatellites (CSF1PO, TPOX, THO1, VWA, D16S539, D7S820, D13S317, D5S818, F13A1, FESFPS, F13B, LPL) were estimated from three departments from Northwestern Colombia. The total number of samples analysed was 1045 individuals.Comparative analysis among the three studied departments and with other published Colombian populations were also performed and discussed.     

试论人口萎缩对国家安全的影响

从国家安全的角度来看,一个国家必须保持一个适度的人口规模,不仅是因为民族及文化得以延续的需要,也是正常进行社会分工的最起码的条件。而人口的过度萎缩会给工业国家带来国家和民族的“集体自杀”、人口的过度老龄化以及民族结构的改变等对国家安全的不利影响。对中国而言,适度的人口萎缩并不会对中国的文化和种族的延续构成威胁,反而有利于缓解在资源和环境方面所承受的巨大压力,但是过快、过急的人口萎缩会改变中国合理的人口结构,从而引发社会、经济和政治问题,并对国家安全构成威胁。     

Population data of Y-chromosomal STRs in lithuanian, latvian and estonian males

Data of nine Y-chromosomal STRs, the so called “extended core set”, were obtained from 152 unrelated males from Lithuania, 145 from Latvia and 133 from Estonia. The haplotype data reported here have been included into the Y-STR database maintained at the Institute of Legal Medicine, Humboldt-University, Berlin.     

当前户籍制度改革面临的难点与动力基础分析

近年来,要求改革户籍制度的呼声不断。户籍制度改革面临的难点:1.从资源分配上,统一城乡户口并不意味着相关社会问题会随之解决;2.对于大城市户籍改革成本的认识难以统一;3.统一城乡户口意味着流动的双向性。动力基础:1.城市拉力不断提升;2.农村推力经济的持续发展;3.实现比较利润的平衡化。     

Human Y-specific STR haplotypes in a Slovenian population sample

The allele distribution of the systems DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385 and YCAII were investigated in a sample of 121 unrelated males from Slovenia     

美国华侨华人政治经济发展新形势及对我国政策建议

通过对近期美国华侨华人人口、职业构成、企业家实力、社团运动、联邦与地方参政情况等政治经济发展的主要方面进行阐述与分析,探讨在中美关系大背景下,美国华侨华人政治经济发展遇到的新问题与新机遇,以及其在中美关系良性发展过程中扮演的重要角色,由此提出对国家华侨华人政策的相关建议。