An STR database on the Volga-Ural population

This work develops a reference STR database on the Volga-Ural population, Russia, comprised of 640 individuals that were sampled from eight ethnic groups (Finno-Ugric Mari, Mordva-Moksha, Mordva-Erzja, Komi-Permjak, and Udmurt, and Turkic-speaking Bashkir, Tatar-Mishary, and Chuvash) and typed with 10 autosomal STR markers: TH01, CSF1P0, FGA, vWA, D3S1358, TPOX, D16S539, D8S1179, D13S317, FES. The groups differentiate in allele frequencies, and therefore we computed θ-values between allele frequencies in each ethnic groups and those in the database as a measure of their differentiation. Nevertheless, the Volga-Ural ethnic groups form a relatively compact cluster that greatly deviate from the Romanic Moldovans and the Turkic Yakuts, taken for comparison, and are closer to the Slavic Russians, Belarusians, and Ukrainians, although significantly differ from those as well.     

Developing STR databases on structured populations: The native South Siberian population versus the Russian population

Developing a forensic DNA database on a population that consists of local ethnic groups separated by physical and cultural barriers is questionable as it can be genetically subdivided. On the other side, small sizes of ethnic groups, especially in alpine regions where they are sub-structured further into small villages, prevent collecting a large sample from each ethnic group. For such situations, we suggest to obtain both a total population database on allele frequencies across ethnic groups and a list of θ-values between the groups and the total data. We have genotyped 558 individuals from the native population of South Siberia, consisting of nine ethnic groups, at 17 autosomal STR loci of the kit packages AmpFlSTR SGM Plus и AmpFlSTR Profiler Plus. The groups differentiate from each other with average θ-values of around 1.1%, and some reach up to three to four percent at certain loci. There exists between-village differentiation as well. Therefore, a database for the population of South Siberia is composed of data on allele frequencies in the pool of ethnic groups and data on θ-values that indicate variation in allele frequencies across the groups. Comparison to additional data on northeastern Asia (the Chukchi and Koryak) shows that differentiation in allele frequencies among small groups that are separated by large geographic distance can be even greater. In contrast, populations of Russians that live in large cities of the European part of Russia are homogeneous in allele frequencies, despite large geographic distance between them, and thus can be described by a database on allele frequencies alone, without any specific information on θ-values.     

保障流动人口合法权益 促进厦门和谐社会建设

随着厦门市经济发展和社会进步,流动人口劳工总量呈稳步上升之势.虽然厦门市在保障流动人口权益、促进厦门和谐社会建设方面取得了显著成绩,但还存在着一些问题,为此应采取措施,保障流动人口合法权益,促进和谐社会建设.     

Analysis of 124 SNP loci included in HID Ampliseq identity panel in a small population of Rio de Janeiro,Brazil

Implementation of massively parallel sequencing platforms can bring a great contribution to Forensic Genetics field, with a great saving of time and costs, as well as allowing reliable results to be obtained from small or extremely degraded samples. The aim of this work was to analyze 124 SNP loci (90 autosomal and 34 Y-SNP) included in HID-Ion Ampliseq Identity Panel in a small sample from Rio de Janeiro state, Brazil. Samples from 12 non-related individuals were amplified with HID-Ion Ampliseq Identity Panel and sequenced on the Ion Torrent PGM platform (Thermo Fisher Scientific); genotypes were generated with HID SNP Genotyper plugin and forensic parameters were calculated with PowerStats v.12. All samples were successfully genotyped and were used to calculate allele frequencies, homozygosity, heterozygosity, random match probability (RMP) and exclusion power for all 90 autosomal SNP loci. Using the formula proposed by Budowle et al. (1996), only 4 of the 90 loci genotyped (4,4%) showed allele frequencies below the minimum required. It means that although a small set of individuals was used on this study, it may have shown a good perspective of Rio de Janeiro state allele frequencies. Among the 11 male samples analyzed, a prevalence of the haplogroup R1b of Y chromosome was observed, followed by the haplogroups E, Q and J. Such distribution reflects the results demonstrated in other studies for the population of Rio de Janeiro. All results together demonstrate the usefulness and applicability of SNP analysis on Ion Torrent PGM.     

浅议统计学原理教学中多媒体辅助教学手段的利用

文中分析了统计学原理教学引进多媒体辅助手段的重要性,并就多媒体教学中应着重解决的问题进行了探讨。     

Violent Crime in the Urban Community: A Comparison of Stockholm and Basel

In this article the authors present some preliminary findings from a comparative study of police recorded violent crimes in Stockholm and Basel. They present the first results from a comparative analysis of the situational context, the ecology of crime, and of offender residences in these cities. There is impressive evidence of basic similarities in the situational context of violent crime and the residential distribution of violent offenders. Yet there are also significant differences, some of which may have interesting implications for crime prevention. Firstly, violent crime seems to be more highly concentrated during weekend nights in Stockholm than in Basel. Secondly, they find evidence that the presence of weapons in a community increases the risk of more serious outcomes of violent events. Efforts to reduce the availability of weapons may thus have significant effects on the outcomes of violence, but not necessarily on its frequency. Thirdly, they show that offenders in both cities are highly concentrated in socially disorganised communities with few economic and social resources.     

Juvenile Crime Trends in Post-War Europe

In the literature, two models - routine activity and social control - are most often used in attempts to account for a continuous upward trend in the number of juvenile offenders during the post-war period. In Sweden, contrary to what we might expect given these models, the number of juvenile offenders has been stable, and may even have decreased, over the last 25 years. This article will present an analysis of juvenile crime trends in West European countries during the post-war period (1950-1995). A sensible way to begin a comparative study is to take advantage of the analyses already carried out by researchers in the relevant countries. Besides the official crime statistics this study also uses alternative statistics, that is, self-report studies and victim surveys. An obvious advantage with these surveys is that they are independent of the relevant country's judicial system and official statistics. The availability of data played an important part in the choice of countries to be included. In addition, contacts were established with researchers and research centres in most countries covered by the study.     

Genetic polymorphism of 30 autosomal InDel loci in Chinese Hainan Li population

A novel genetic marker, Insertion/Deletion polymorphism (InDel) shows remarkable potential for forensic DNA applications. Hainan Island is the southernmost and the second largest island in China, of which the Li ethnic group is regarded as the original inhabitants. In this study, 207 individual samples of Li ethnic group from Hainan were genotyped using Investigator DIPplex kit which contains 30 autosomal InDels and Amelogenin. Allele frequency and forensic parameters were calculated for these loci. Several deviations from Hardy-Weinberg equilibrium (HWE) and linkage disequilibrium (LD) may indicate founder effect in the Li ethnic group. The combined power of discrimination (CPD) and the cumulative probability of exclusion (CPE) reached 0.99999999992912 and 0.9861, respectively. These results suggested that the kit was effective for personal identification in Hainan Li population. The population comparisons through the Nei’s standard genetic distance (R_st), phylogenetic tree, multidimensional scaling analysis (MDS), principal component analysis (PCA), and STRUCTURE analyses along continental divisions manifested that the 30 InDels panel had a certain intercontinental differentiation ability.     

数字化背景下老年友好社区构建策略——基于杭州市K街道N社区的调查

近年来,我国数字城市、5G运用、未来社区建设的推进,改变了老年人的社区养老环境,老年友好社区作为我国社区研究中的一个重要组成部分,亟待对其在数字城市背景下的构建内容、实践与评估、发展趋势开展深入探究。本研究通过对杭州市K街道N社区数字化背景下的老年友好社区构建的满意度调查,分析了数字化背景下的老年友好社区构建与老年人日常生活的关系、与原居养老的关系、与代际互动的关系以及融入的意愿度,认为这是老年友好社区的构建内容从单一的物质环境向多维度转变、构建主体由政府单一型向老年人参与及多主体合作型转变,探索形成良好代际互动的全龄社区的内在机制。