Staphylococcal scalded skin syndrome mimicking child abuse by burning

Determining the cause for the sudden death in young adults tends to be complex and difficult. Two cases of death of young people were autoptically investigated who died suddenly while carrying out their hobbies (a 22-year-old male musician and a 20-year-old female dancer). In both cases neither the police investigation, the autopsy, nor the toxicological investigations gave any relevant results. However, when investigating the histology fatty and fibrotic tissue in the right ventricle of the myocardium were found, whereas the myocytes proved to be degenerated--typical for arrhythmogenic right ventricular cardiomyopathy (ARVC). It is important to consider the possibility of heart rhythm failure if a clear reason for sudden death in young adults cannot be detected. Heart rhythm failure often involves the genetic background of the case, which suggests that genetic analysis should be carried out as a supportive means of diagnostics.     

论我国在押人员死亡调查制度之完善

在现行制度下,在押人员死亡后,没有一个独立于监管部门的外部机构进行独立调查,也没有社会力量能参与到整个调查过程中,相关部门给出的调查结论往往面临很多质疑。长此以往,国家权力的公信力将受到严峻挑战。为此,应借鉴英国经验,深化改革,以立法明确在押人员死亡的调查由检察机关主导,社会力量参与;同时,通过举行公开听证、公布调查报告等,满足社会公众的知情权,确保调查程序的正当性。     

A comparison of wrongful convictions in death penalty cases between China and the United States

In recent years, both China and the United States (US) have discovered numerous wrongful convictions, including several cases in which innocent people have been sentenced to death. These discoveries have led both countries to reform the death penalty but the extent and nature of the reforms in each country have been greatly different. This article explores the similarities and differences between the nature of wrongful convictions in death penalty cases in China and the US. It will also compare the reforms undertaken in each country. On the whole, the US has made greater progress in the prevention and correction of wrongful convictions involving the death penalty, especially in the areas of evidentiary rules and post-conviction review. In order for China to match America's success, it is necessary that China adopt more substantive reforms. China should learn from America's experience and should continue to adopt international standards of criminal justice, such as due process rights, the presumption of innocence and the exclusion of illegally obtained evidence. In the interim, China should immediately suspend all executions until adequate reforms can be carried out. Ultimately, China should surpass the US in criminal-justice reform and in the field of human rights protection by completely abolishing the death penalty and creating a more effective mechanism for criminal punishment.     

Genetic variability of RyR2 and CASQ2 genes in an Asian population

We analyzed the coding regions of the cardiac calcium-handling genes, ryanodine receptor 2 (RyR2) and calsequestrin 2 (CASQ2) for genetic variants in a healthy Chinese population (n = 95) and in a cohort of 28 sudden unexplained death victims. Mutations in RyR2 and CASQ2 have been shown to alter calcium homeostasis during excitation–contraction coupling and predispose individuals to fatal cardiac arrhythmias. The genetic screening was accomplished by denaturing high-performance liquid chromatography and DNA sequencing methods. Genetic analysis revealed the following non-synonymous genetic variations: two reported RyR2 polymorphisms; 5654G>A (G1885E) and 5656G>A (G1886S), two reported CASQ2 polymorphisms; 196A>G (T66A) and 226G>A (V76M) and one novel CASQ2 mutation; 529G>C (E177Q). The functional significance of the novel CASQ2 mutation has not been evaluated and characterized. This study shows that multiple genetic variations of the RyR2 and CASQ2 genes exist in the two study populations. The inter-individual genetic variability may underlie the different susceptibility of individuals to developing ventricular tachycardia. The research results will be valuable for which future work involving clinical and forensic samples can be based upon to distinguish potential disease-associated mutations from common polymorphisms.     

Mahaim纤维致猝死5例

寻找心源性猝死者的病理形态学诊断依据。采用本组建立的心传导系统检查法 ,对 16 5例无心外器官疾病猝死者的心脏 ,作心传导系统的组织学检查。发现 5例存在心传导系统Mahaim纤维 ,全部均为束室束型。本组Ma haim纤维的形态学与房室束 (HB)或左束支 (LBB)相似 ,胞体横径在 10～ 35 μm左右 ,胞浆丰富 ,色淡红染 ;来自HB的纤维胞体呈细条状 ,核居中 ;来源于LBB的则按其始发点不同自上而下逐渐变大 ,纵切细胞未见分叉 ,但部分细胞周围见有一薄层结缔组织包围。分析结果表明 ,Mahaim纤维是可致猝死的房室传导旁路。     

191例急死死因分析

本文对191例急死法医病理检案资料进行统计分析，结果表明急死年龄以15～59岁为多，共154例（占80．63％）。死因以心血管系统疾病为多，80例（占41．88％），但5岁以下以呼吸系统疾病为多；在191例急风中，以冠状动脉疾病最多，共55例（占28．80％），其次为小叶性肺炎21例（占10．99％）和急性出血性胰腺炎（12例占6．28％）。死亡诱因多为纠纷／或轻微外伤87例（占45．55％），另有51例（占26.70％）死前有轻微临床症状体征，经医生诊治用药后很快死亡，从而引发医疗纠纷。     

试析《论犯罪与刑罚》中关于死刑的法律思想

死刑是对犯罪分子最严厉的处罚,也是最古老的刑罚之一,自死刑产生后的几千年,被历代统治者奉为"治国法宝",没有人质疑它存在的合理性."近代刑事法之父"贝卡利来在<论犯罪与刑罚>中最早对死刑的残酷性提出尖锐的批判,由此引发关于死刑存废的争论.本文着重探究贝卡利来主张废除死刑的积极思想,以期对死刑制度进行理性的再反思.     

羊水栓塞致产妇猝死的免疫组织化学研究

羊水栓塞是引起产妇猝死的最常见原因之一,作者们应用免疫组织化学、免疫酶标法技术,对52例产妇死亡的尸体解剖材料进行了分析研究,确定12例是由羊水栓塞引起的产妇猝死。确认采用免疫组织化学的方法可提高法医病理工作者对诊断羊水栓塞的准确性和科学性。     

青年人CCS脂肪超前变化致猝死

为研究心传导系统（CCS）与猝死的相互关系，对120例心性猝死者CCS作常规检查，光镜下作半定量计算其脂肪含量。结果发现：9例经一般常规尸检未找到任何致死原因的青年人（30岁以下），其房室结（AVN）与房室束（HB）的脂肪组织含量为70％，比同龄人明显增多，致使结、束肌细胞被脂肪分割中断或压迫萎缩。结内外细胞连接不足或缺失是构成心电不稳的病理基础。此外本文尚对其脂肪浸润的病因发病，猝死机理作了探讨。     

心肌炎侵及心传导系统病理学观察

本研究采用已建立的人体心脏传导系统简易取材法,对6例心肌炎的案例进行了传导组织的病理学观察,结果发现6例心肌炎患者CCS均有明显炎症,尤以SAN、AVN病变为主;推测CCS炎症可能为心肌炎患者猝死的主要原因。因此,本文提出对怀疑心性猝死案例应作常规传导系统检查。