香港商业罪案调查的主要特点及其借鉴意义

香港作为国际性的贸易和金融中心,其商业犯罪案件具有典型性。香港警方对付商业犯罪,也具有特点。主要是有完善的易于操作的法例,能动的侦查机制,网络化的联动查案方式以及高度专业化的人力支援等。这些方面对于中国大陆都有借鉴意义。     

活血通脉颗粒对真性红细胞增多症患者血栓弹力图K值的影响

目的 观察活血通脉颗粒治疗真性红细胞增多症（polycythemia vera,PV）的临床疗效,及其对血栓弹力图K值的影响。方法 随机将60例PV患者分为试验组、对照组各30例。对照组给予西药羟基脲治疗;试验组在对照组的基础上加用活血通脉颗粒。治疗6个月后,观察和比较两组PV患者临床疗效、中医证候评分、外周血象及血栓弹力图K值。结果 两组患者临床疗效分布比较,差异具有统计学意义（P<0.05）;两组患者治疗后证候评分均较治疗前显著降低（P＜0.05）,试验组治疗前后中医证候评分差值显著大于对照组（P＜0.05）;两组治疗后血常规各项指标均较治疗前显著降低（P＜0.05）,试验组治疗前后血小板计数差值显著大于对照组（P＜0.05）;两组患者治疗后血栓弹力图K值均较治疗前显著升高（P＜0.05）,试验组升高至正常值范围,其升高值显著大于对照组（P＜0.05）。结论 活血通脉颗粒可明显改善PV患者中医证候及外周血象,并通过诱导血小板表面受体表达,改善PV患者凝血功能。     

促进罪犯回归社会：英国的实践

促进罪犯重新融入社会是当代英国的重要刑罚目标。为此,立法上规定有监禁刑与半监禁刑,监禁刑执行中规定有刑期管理、家庭监视等制度。这对我国不无借鉴意义。     

英国软件反向工程适用立法探讨

软件反向工程在现代社会具有极其重要的作用，但滥用则会违背知识产权之根本保护法理，理应受到法律规制。英国是一个软件反向工程适用立法较完备的国家，其主要适用欧盟相关立法《软件指令》和本国专门性立法《软件条例》。     

气相色谱/质谱检验合成大麻素K3中AKB48

目的建立较为快速准确的合成大麻素K3中AKB48的气相色谱/质谱检验方法。方法对进样口温度、初始柱温、柱流速及质谱采样率等4项色谱及质谱实验参数进行考察优化。结果 GC/MS检验合成大麻素K3中AKB48的优化条件为:进样口温度280℃,柱初始温度80℃,柱流速为2.0ml/min,质谱采样率为2。结论该方法具有快速、准确、灵敏等优点,可用于K3中AKB48的定性检验鉴定。     

浅谈武术散手中边腿技术的重要性及教学要点

边腿具有攻击时起动速度快、进攻点多、使用和命中率高、得分多等特点,它是武术散手实战中的一项重要技术。在边腿技术教学中,我们要注意正确的基本技术、良好的战术意识、过硬的身体素质和专项素质这三个教学要点,理论联系实践,循序渐进。     

蛋白酶K-Chelex100法提取肋软骨DNA技术的优化

目的优化蛋白酶K的用量和消化时间,用于提取肋软骨DNA。方法 30份肋软骨样本各取大小为0.2cm×0.3cm×0.4cm的软骨块5份,分别编为A～E组。采用不同蛋白酶K用量和消化时间的Chelex100方法,提取5组各30份软骨块DNA,进行DNA定量、采用Sinofiler试剂盒扩增后进行电泳检测,采用非参数检验法比较检验成功率。结果 A～E组样本中采用加入2μL蛋白酶K并消化30min的D组方法成功率最高(96.7%),组间差异具有统计学意义。结论采用蛋白酶K-Chelex100方法,选择加入2μL蛋白酶K,消化30min可有效提高肋软骨DNA分型检验成功率。     

Mary Wollstonecraft’s divergent attitudes towards trust

ABSTRACT

Mary Wollstonecraft is increasingly being recognized as a philosopher who made a noteworthy contribution to moral and political philosophy. Her work not only encompassed political treatises, such as the now well-known A Vindication of the Rights of Woman, but also fiction. This article demonstrates how Wollstonecraft’s work comprised three main ways of engaging with trust, namely distrust, virtuous trust, and open trust. It puts these three forms of trust into context with Wollstonecraft’s ambivalent relation to the 18^th-century culture of sensibility. Moreover, Wollstonecraft’s open form of trust is compared with the 20^th-century Danish theologian and philosopher K. E. Løgstrup’s conception of trust. Løgstrup regarded genuine trust as a spontaneous, basic phenomenon that was not rooted in moral reasoning. While there are some similarities between Wollstonecraft’s open trust and Løgstrup’s understanding of trust, Wollstonecraft ultimately reinforced the value of ‘an educated heart’, namely the idea that the feelings of the heart should be cultivated by reason. Accordingly, this article offers some insight into how we may perceive Wollstonecraft’s strong rejection of Edmund Burke’s ‘inbred sentiments’, that is, Burke’s belief in innate, benign moral instincts.     

二参真武汤调控PI3K/AKT/mTOR信号通路抑制心肌纤维化的体外实验研究

目的 探究二参真武汤抑制心肌细胞纤维化的作用机制。方法 采用灌胃给予SPF大鼠二参真武汤、贝那普利7 d的方法制备含药血清,从出生3 d内的乳鼠心脏中提取原代心肌成纤维细胞,采用免疫荧光和台盼蓝染色法鉴定细胞纯度与成活率,采用CCK-8法确定二参真武汤含药血清的最佳给药浓度与给药时间,采用血管紧张素Ⅱ(angiotensinⅡ,AngⅡ)刺激原代心肌成纤维细胞复制心肌纤维化模型,将原代心肌成纤维细胞分为正常组、模型组、二参真武汤组、贝那普利组,采用ELISA法检测胶原蛋白(collagenase, Col)-Ⅰ和Col-Ⅲ含量,采用Western blot法检测平滑肌肌动蛋白(alpha-smooth muscle actin, α-SMA)、Col-Ⅰ、Col-Ⅲ、PI3K、p-PI3K、AKT、p-AKT、mTOR、p-mTOR蛋白表达水平,qRT-PCR法检测α-SMA、Col-Ⅰ、Col-Ⅲ、PI3K、AKT、mTOR mRNA表达水平。结果 提取的原代心肌成纤维细胞纯度与成活率均达到95%以上。与正常组比较,模型组、Col-Ⅰ、Col-Ⅲ含量显著升高(P<0.05),α...     

Tominaga Nakamoto and the Origin of Japan's Oriental Studies

Tominaga Nakamoto, a Japanese scholar of the early 18th century, changed the basic pattern of Japans Buddhist and Confucianist studies with his books Shutsujō Kōgo (Words after Enlightenment) and Okina no Fumi (The Writings of an Old Man). In the former book, based on his analysis of Chinese culture in terms of Confucianism and Indian culture from the viewpoint of Buddhism, he compared Indian, Chinese and Japanese culture and summarized their characteristics with the words “fanciful”, “elegant” and “simple” respectively. In the meantime, in combing through the development of Buddhism he put forward a set of key concepts in relation to his research methodology, extending his domain from country-specific studies to Asia regional studies and finally Oriental studies. In the latter book, he used the concept “makoto”, roughly meaning “practicing the good”, to synthesize the Way of the three nations. His study transformed Japanese Confucianism and Buddhism from a system of belief to an academic field. Despite his rational analysis and criticism of the traditional oriental culture, Tominaga consciously identified with it and inherited it. As the first scholar in early modern Japan who developed his own research methodology, Tominaga is the trailblazer of Oriental studies.