肝癌并发上消化道出血的危险舌象分析

目的:以望舌为主了解原发性肝癌并发上消化道出血的危险因素,为临床预防提供依据。方法:收集737例原发性肝癌患者的临床资料,并使用标准化舌象采集环境获取其临床舌象,由医学专家给出舌象诊断,使用条件Logistic回归对肝癌并发上消化道出血的危险因素进行筛选。结果:舌色按由淡白、淡红到红进行分类,结果显示上消化道出血的主要危险因素主要与肝癌临床分期(OR=3.607,P=0.000)、舌形异常(OR=3.295,P=0.005)、舌下脉形状(OR=1.558,P=0.008)和血清总胆红素水平(OR=1.008,P=0.015)有关;而舌色按紫与不紫进行分类,结果显示舌色也与肝癌并发上消化道出血密切相关(OR=1.989,P=0.047)。结论:舌体胖大、舌下脉增粗或迂曲、舌色见紫、肝癌临床分期进展和血清胆红素水平过高均为上消化道出血的危险因素,以舌象观察为主可望作为一种预测肝癌并发上消化道出血的简捷方法。     

Diversity of 17-locus Y-STR haplotypes in Upper (Southern) Egyptians

Seventeen Y-STR loci included in the AmpF?STR^® Yfiler™ PCR Amplification kit were typed in a population sample of 208 males from Upper (South) Egypt. Of 204 observed haplotypes, 200 were unique (96.6%) and 4 were found twice each. The 17 loci gave a discriminating power of 0.9998. DYS458 showed the highest diversity as a single-locus marker (h = 0.868) along with a high frequency of microvariants and new alleles (22% of the sample). Other loci revealed duplicated and null alleles. Comparative analysis with Y-STR datasets of relevant populations and submission of the haplotypes to the Y-STR Haplotype Reference Database (YHRD) were undertaken.     

电针关键肌结合“颈—肩—胸”调整术治疗颈型颈椎病伴上交叉综合征的随机对照研究

目的 探讨电针关键肌结合“颈—肩—胸”调整术对颈型颈椎病伴上交叉综合征患者的临床效果。方法 选取颈型颈椎病伴上交叉综合征患者70例,采用随机数字表法分为对照组和观察组,每组35例,对照组采用电针关键肌治疗,观察组在电针关键肌的基础上采用基于“筋骨并举”思想的“颈—肩—胸”调整术治疗。治疗前后分别运用中文版颈部疼痛和废用量表（Chinese version of neck pain and disability scale,SC-NPDS）对患者颈椎疼痛水平、功能、残疾及情绪和认知进行评分,测量治疗前后颈椎活动度的改变以及前肩角度（forward shoulder angle,FSA）、头前伸角度（forward head angle,FHA）的变化。结果 与治疗前比较,两组治疗后SC-NPDS评分、FSA、FHA显著降低（P＜0.05）,颈椎左旋、右旋、左右侧屈、屈曲、伸展活动度显著升高（P＜0.05）;两组患者治疗前后SC-NPDS评分、颈椎活动度及FSA、FHA差值比较,差异均有统计学意义（P＜0.05）。结论 电针关键肌治疗颈型颈椎病伴上交叉综合征能减轻患者疼痛,改善颈椎大部分活动度及前倾姿势,而在此基础上采用“颈—肩—胸”调整术更能有效减轻患者疼痛,改善颈椎活动度,纠正患者静态头颈部前倾姿势。