人外周血FoxO3a mRNA表达随龄变化规律的初步研究

目的评估人外周血中FoxO3a mRNA表达的随龄变化规律,为法医学个体年龄推断寻找新的分子指标。方法采集80个健康无关个体血样,按年龄分为8组:≤9岁、10～19岁、20～29岁、30～39岁、40～49岁、50～59岁、60～69岁、≥70岁组,每组10人。提取总RNA后,用实时定量RT-PCR技术检测FoxO3a mRNA的表达水平。结果人外周血FoxO3a mRNA表达随年龄的增长而逐渐增加,具有良好的相关性(r=0.841,P0.01),以年龄分组为自变量,FoxO3a mRNA表达水平为因变量,可得拟合曲线Y=0.001e0.418x。结论人外周血中FoxO3a mRNA表达具有较强的年龄特征,有望成为年龄推断的有用指标之一。     

利用牙齿推断年龄的研究进展

牙齿是人体最坚硬的器官之一,其抗腐蚀能力强,多项形态特征具有增龄性变化,因此利用牙齿推断年龄在法医学中得到广泛应用。由于牙齿的生理性变化的复杂性及环境因素的影响,不同牙齿推断年龄的方法各具其应用价值,同时也存在一定的局限性,法医工作者需要依据具体情况选择适合的方法并加以综合运用,以提高年龄推断的准确性。本文对国内外利用牙齿推断年龄的研究现状进行综述,并对各种推断方法进行比较评价,希望能为相关研究和实践提供参考。     

Mighty Morphin’ age progression: how artist,age range,and morphing influences the similarity of forensic age progressions to target individuals

When children go missing, authorities sometimes release age progressed images that are intended to approximate the person's current appearance. The current studies measured the influence of the range between the time when the child went missing and the age portrayed in the age progression on the similarity between the progressions and current images of the targets. Experiment 1 examined whole face images and Experiment 2 examined internal features only. Eight artists were recruited to produce progressions at three age ranges. Also included were averaged (morphed) images made of progressions of the same individual at a given range by different artists. Progressions across shorter ranges produced images more similar than those across longer ranges, and target comparisons yielded higher similarity ratings than foil comparisons. Although there was much variability among artists, the morphed images performed better than the average rating given to all age progressions.     

Differing patterns of marriage between a city and villages in 18th century Korea: The case of Taegu Area

While the urban area was increasingly filled with middle- and low-status residents, the rural area was dominated by high-status settlers whose number increased because of migration from the city and natural growth. Remarkable differences existed between urban and rural marriage features such as marriage age and rate of remarriage. The more sincere adoption of the high-status marriage culture in the rural area may be attributed to its occupational homogeneity. In the rural agrarian settings, landlords, self-cultivators and tenants shared a similar living pattern and value system based on the agricultural cycle. The urban area, however, exhibited a variety of work patterns of local functionaries, artisans and merchants. Many middle- and low-status people might well have found the high-status culture of the rural area incompatible with their own.     

Violence against women as conveyed by surveys – the Finnish case

The methodological choices made in a survey may partly shape the picture a survey conveys of partnership violence. This article considers some of the choices made in the Finnish survey on violence against women, such as the way the violence was defined and how the definition tried to take into account the special characteristics of this kind of violence, in order to help the respondents to identify and recall different events of it. The empirical analyses showed that the used definition of violence had not reached all the respondents representing different population groups. The experiences of partner violence among older, less educated women, and the experiences of those who felt embarrassed or ashamed to speak about issues concerning their partner or partnership, were more probably under-represented in the survey.     

城市社区老年群体就医行为影响因素分析

日益增长的老年人健康需求是老龄化带来的诸多挑战中的一个重要方面。新一轮医药卫生体制改革突出强调基本医疗服务供给和基层卫生服务体系建设,在缓解老年人健康压力方面有一定的积极作用。老年人在身体条件、经济能力、思想观念等方面的特点,使得其就医行为受到机构服务能力、距离、费用、就医过程等多方面因素影响。在新医改背景下,需要结合这些影响因素继续完善基层医疗服务体系,以更好地满足老年群体健康需求。     

Pronasale Position: An Appraisal of Two Recently Proposed Methods for Predicting Nasal Projection in Facial Reconstruction

This study examines two recently proposed methods for predicting nose projection from the skull, those developed by Stephan et al. (Am J Phys Anthropol 122, 2003, 240) and Rynn et al. (Forensic Sci Med Pathol 6, 2010, 20). A sample of 86 lateral head cephalograms of adult subjects from Central Europe was measured, and the actual and predicted dimensions were compared. Regarding nose projection (the anterior and vertical position of the pronasale), in general, the method of Rynn et al. (Forensic Sci Med Pathol 6, 2010, 20) was found to perform better and with less error variance than the method of Stephan et al. (Am J Phys Anthropol 122, 2003, 240), but the mean difference between the actual and predicted values did not exceed 2.2 mm (6.5% of the actual dimension) in most of the variables tested. The vertical dimensions of the nose were predictable with greater accuracy than the horizontal dimensions. Although the mean error of both methods is not great in practice and thus both methods could be considered to be “accurate,” the real variance of error should not be overlooked.     

Dental Age Assessment in Children: A Comparison of Four Methods in a Recent French Population

The aim of this study was to analyze the accuracy and the reliability of four methods of dental age estimation (Demirjian, Willems I, Willems II, and Chaillet standards) in a French population. Orthopantomograms of 743 children aged between 4 and 15 years were used. The Demirjian standards gave a consistent overestimation of dental age compared with chronological age (+0.45 and +0.46 years for girls and boys, respectively). We found that three modified methods were more accurate for both sexes than Demirjian's method: the Willems I method appeared to be more suitable when the sex and ethnicity are both known (?0.09 and +0.14 years for girls and boys, respectively); the Willems II method was more accurate for children of unknown sex (mean difference = 0.00 years), and the Chaillet method was found to be more accurate than the Demirjian method, but less accurate than the Willems I method (?0.59 and ?0.18 years for girls and boys, respectively).