87例大脑及脑干挫伤HSP70变化的研究

目的探讨人大脑及脑干挫伤后神经细胞HSP70变化与损伤时间的关系及大脑与脑干HSP70变化的差异。方法对87例闭合性颅脑损伤死亡脑挫伤组织进行病理学及HSP70免疫组织化学染色,结果进行图像分析。结果脑挫伤24h后.HSP70阳性神经细胞最多见,且免疫反应性最强,随后逐渐下降,14d组及30d组HSP70表达与对照组类似。脑挫伤部位可见较多HSP70阳性的淀粉样小体。图像分析显示大脑与脑干HSP70阳性细胞3个参数(A、IOD及AOD)之间呈高度显著正相关或显著正相关,由高至低排列为:A>IOD>AOD。结论神经细胞HSP70免疫组化染色结合图像分析技术作为推断脑挫伤经过时间的参考,大脑与脑干挫伤后神经细胞HSP70变化规律基本一致,但脑挫伤灶周围淀粉样小体形成的意义有待于进一步研究。     

应用斑点ELISA快速进行体液(斑)的血型测定

<正> 在法医学上体液(斑)的血型测定一般常规应用中和试验、吸收试验、解离试验及混合凝集反应。这些试验既耗时,又需较高的技术,且要新鲜标准红细胞指示结果。本实验系应用我们自己提纯标酶的抗-A,-B与抗-H单克隆抗体A,利用斑点ELISA来进行体液(斑)的血型测定。通过颜色变化直接判断血型。     

Exploring a New View： Judicial Activism of Justice Attestation Quantitative Analysis fromPerspective of Procedure

随着社会经济的迅速发展，司法实践对法官能力提出了更高的要求。赋予法官司法能动权，改变传统的司法运行模式，不仅需要在刑事诉讼中营造有助于法官能动性发挥的外部环境，还要探寻激励法官能力提升的内在因素。刑事认证程序是法官发挥司法能动性的重要领域，通过对这一阶段法官心证的定量化分析，可以直观掌握不同因素影响法官司法能动性发挥的现状，进而采用合理搭配各学历层次法官比例、优化法院内部考核及选任方式、培养法官整体性思维等方式提升法官能动性的发挥。     

论法律理论的方法及其性质——基于分析法理学的视角

在从事具体的法律理论工作之前,我们必须澄清围绕在法律理论四周的种种误解,确立恰当的研究方法以及厘清法律理论的性质。从分析法理学的视角来看,法律的概念分析就是对法律之本质的探究。分析法理学这一方法论的基本论题需从以下四个方面来理解:一是法律的概念分析不是对法律概念的语义分析;二是概念分析是对法律之必然属性的探究,是对法律这种特定制度性类型的探究,从根本上讲,这是对属于我们的法律概念之自我理解;三是一种合格的法律理论只能是评价性或证立性的;四是法律理论的普遍性不仅不排斥地方性,而且要以地方性为出发点。     

有限责任内涵的实证分析——一种公司损失分摊的法律规则

有限责任既不是公司的法律责任,也不是股东的法律责任,而是一种公司损失的分摊规则。从实证角度分析,有限责任是股东分摊公司"有限损失"的一种制度设计。根据有限责任规则,股东对公司损失实行"定额分摊",而社会﹙主要但不限于债权人﹚则实行"余额分摊"。鉴于公司损失涉及到社会分摊问题,公司不仅是"利益共同体",也是"损失共同体",这是公司相关制度刚性设计的基础。     

microRNA Detection in Blood,Urine, Semen,and Saliva Stains After Compromising Treatments

Evaluation of microRNA (miRNA) expression as a potential method for forensic body fluid identification has been the subject of investigation over the past several years. Because of their size and encapsulation within proteins and lipids, miRNAs are inherently less susceptible to degradation than other RNAs. In this work, blood, urine, semen, and saliva were exposed to environmental and chemical conditions mimicking sample compromise at the crime scene. For many treated samples, including 100% of blood samples, miRNAs remained detectable, comparable to the untreated control. Sample degradation varied by body fluid and treatment, with blood remarkably resistant, while semen and saliva are more susceptible to environmental insult. Body fluid identification using relative miRNA expression of blood and semen of the exposed samples was 100% and 94%, respectively. Given the overall robust results herein, the case is strengthened for the use of miRNAs as a molecular method for body fluid identification.     

Transphobic discourse and moral panic convergence: A content analysis of my hate mail

Recently, new social anxieties about transgender people have begun to emerge, framed as an issue of “grooming”—a term typically used in the context of child sexual abuse. In this way, moral panic about transgender people seems to be merging with oft-repeated social fears about pedophilia, resulting not only in policies criminalizing trans people and their allies but also in escalating hatred and threats toward trans-affirming educators. This pattern requires further inquiry. As a trans academic who has been at the center of moral panic, my own hate mail can provide material for this exploration. I conducted a content analysis of 231 letters and e-mails sent to me containing messages of hate, to answer the following research questions:

1. What beliefs and understandings did my correspondents indicate having about me and my research?
2. To what extent did my correspondents’ beliefs and understandings about me reflect intersecting contemporary moral panics around trans and queer people, pedophilia, and educators?
3. What stated or implied goals did my correspondents aim to achieve by writing to me?

The findings of this study can add to understanding of how moral panics can converge, and the consequences of their convergence for marginalized groups in academia and beyond.     

气相色谱法快速分析人血、尿中地芬尼多

目的建立人血、尿中地芬尼多的气相色谱快速分析方法。方法用氯仿提取血、尿中的地芬尼多,采用气相色谱法进行定性、定量分析。以正常人血浆、尿液为空白样本,分别添加标准地芬尼多及SKF525（内标物）对方法进行考察和优化,并对1例大剂量误服地芬尼多中毒者体液浓度进行快速测定和检测。结果所建方法分析血、尿中地芬尼多的线性范围均为5.0～200.0μg/mL;最低检测限均为1.0μg/mL（S/N≥3）;日内、日间精密度RSD≤5.6%（n=5）;回收率：血≤（106.23±2.05）%;尿≤（104.19±5.51）%。结论该分析方法操作便捷、实用,适用于地芬尼多的临床血药浓度快速监测和法医毒物鉴定。     

THE UTILITY OF THE DEVIANT CASE IN THE DEVELOPMENT OF CRIMINOLOGICAL THEORY*

This article asserts that the deviant case method offers a potential avenue for enhancing theory directed at explaining crime by using more available information to better connect the process of analyzing cases with that of explanatory refinement and elaboration. This approach has facilitated theoretical development in other social sciences and has proven useful where applied in criminological inquiry. Extant research is reviewed, and an empirical example is presented to demonstrate how this approach might be operationalized in criminological inquiry using quantitative methods. Conclusions relevant to future research are considered.     

Granger因果分析模型研究进展

由于时间序列的非平稳性,不具有有限方差,所以高斯—马尔科夫定理不再成立,用普通最小二乘法得到的参数估计不再是一致的,出现伪回归的现象,从而导致错误的因果关系。同时由于时间序列的非线性,常规的线性向量自回归模型难以正确描述经济变量之间的因果关系。从G ranger因果分析模型研究进展情况,可见目前所面临的问题和未来可能的发展方向。