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排序方式: 共有133条查询结果,搜索用时 15 毫秒
101.
冠心病"瘀毒"病因的提出成为防治冠心病的一个新思路,某些危险因素的存在和控制不理想是"瘀毒"病因产生和发展的重要因素.应通过临床研究探索"瘀毒"病因产生的临床表征和微观病理变化,在辨证论治基础上合理应用活血解毒方药对冠心病防治具有重要意义. 相似文献
102.
Shijia Chan 《Journal of forensic sciences》2022,67(1):363-369
Immunoglobulin G4-related disease (IgG4-RD) is a fibro-inflammatory condition that can affect many organs, either simultaneously or metachronously. In recent years, IgG4-related vascular complications of larger arteries such as the aorta and iliac arteries have been increasingly identified. Among vascular complications, coronary artery involvement in the forms of either periarteritis or coronary artery aneurysms (CAAs) has also been reported; however, are very rare in comparison. This case report presents a rare case of a sudden death due to occlusive thrombosis of IgG4-related giant CAAs measuring up to 10 cm in diameter, demonstrates their possible clinical progression, and shows how they can distort normal anatomy which may then pose challenges in the interpretation of postmortem-computed tomography scans. It also briefly discusses the diagnosis of IgG4-RD in arteries, both clinically and in the postmortem setting. 相似文献
103.
Reisha Rijal MBBS Asit Ranjan Mridha MD Sudheer Kumar Arava MD Chittaranjan Behera MD 《Journal of forensic sciences》2021,66(1):403-406
Misdiagnosed PAS confirmed at medicolegal autopsy Pulmonary artery sarcoma (PAS) is a rare disease and usually indistinguishable from acute or chronic thromboembolic disease of the pulmonary arteries. We present a case of pulmonary artery sarcoma in a 54‐year‐old male, who was clinically misdiagnosed as pulmonary thromboembolism. The patient died of disease; however, the actual diagnosis of PAS was made after a medicolegal autopsy. PAS can be a diagnostic challenge for both clinicians and pathologists. In an autopsy case with a clinical suspicion of pulmonary thromboembolism, if there is an abnormal gross appearance in the pulmonary artery, the forensic pathologist should have a high index of suspicion of PAS, which should be ruled out by a histopathologic examination. 相似文献
104.
Isabelle Le Blanc‐Louvry M.D. Ph.D. Fréderique Papin M.D. Emmanuelle Vaz M.D. Bernard Proust M.D. Ph.D. 《Journal of forensic sciences》2013,58(6):1640-1643
After strangulation, cervical arterial injuries (CAI) are uncommon. We report three unusual cases where strangulation induced immediate stroke. CAI were examined using brain CT scan and Doppler ultrasonography in the three cases and then by autopsy in one of the victims. One of the two victims who survived the attempted strangulation had a unilateral carotid dissection, whereas in the other victim, no arterial dissection or thrombosis was observed. As regards the deceased victim, the autopsy confirmed the bilateral dissection showed on CT scan and Doppler ultrasonic examination and revealed that both carotid arteries were dilated up to two times the normal diameter. Microscopic examination showed a major bilateral hemorrhagic dissection of the media with obliterating fibrous endarteritis lesions associated with inflammatory damage. CT scan with arteriography does not demonstrate all the different types of arterial injury, particularly atheromatous embolism, direct compression, or prolonged spasm. Thus, traditional autopsy remains an essential forensic tool after strangulation to show the type of CAI. 相似文献
105.
目的通过运用多层螺旋CT(multi—slicespiralcomputedtomography,MSCT)冠状动脉钙化积分(coronaryarterycalciumscoring.CACS)的方法.评价其在冠心痛(coronaryarterydisease,CAD)猝死案例中的法医学应用价值,为虚拟解剖鉴定CAD猝死探索有效手段。方法收集9例进行法医学鉴定的心源性猝死案例.尸体解剖前均进行MSCT扫描。通过Agatston’s法对每例冠状动脉钙化程度进行定量分析,并计算CACS,钙化积分〉400作为存在CAD的评判标准,并与尸体解剖结果比较。结果经尸体解剖证实CAD猝死的9例案例中仅有2例钙化积分〉400,CACS对CAD的预测率仅为22.2%。MSCT检查与系统尸体解剖均发现CAD猝死案例中普遍存在不同程度肺水肿改变,冠状动脉左前降支较其他分支发生管腔狭窄的发病率高。结论运用MSCT并结合计算CACS可对CAD猝死案例中冠状动脉钙化明显的进行检测,而钙化不明显的需要辅以如尸体血管造影等其他技术。 相似文献
106.
107.
We report a case of a juvenile male with muscle rigidity caused by cerebral palsy who experienced intraoperative sudden death due to pulmonary fat embolism after multiple muscle-release and tenotomy of the bilateral lower limbs. Data were obtained through review of the surgical and anesthesia records, as well as from autopsy and histopathological examination. All surgical procedures were performed within the same operation, beginning with the right lower limb and then proceeding with the left lower limb, with application of a pneumatic tourniquet to avoid intraoperative hemorrhage. Slight changes in the hemodynamics were noticed after release of the right tourniquet. Further, sudden onset of hypotension, severe bradycardia, and a marked decrease in percutaneously monitored oxygen saturation occurred just after release of the left tourniquet when the left limb was raised for casting. The patient died despite immediate and vigorous cardiopulmonary resuscitation. At autopsy performed 20 h after death, examination of the lungs revealed a pale surface, slight edema, and obvious fat droplets in the vessels at the cut surfaces. Histopathological examination with fat staining was notable for the presence of pulmonary fat embolism. These results suggest that restoration of venous return after removal of the tourniquet combined with massive fat embolism from dead spaces was the likely cause of death. 相似文献
108.
109.
给 5 0日龄蛋用鸡经翼静脉注射内皮素 1(endothelin 1,ET 1)ETA受体 (ET 1的选择性受体 )的特异性拮抗剂BQ12 3,采用右心导管法通过生理多导仪测定蛋用鸡肺动脉收缩压和舒张压。结果显示 ,ETA受体拮抗剂BQ12 3能够使蛋用鸡肺动脉收缩压和舒张压明显下降 ,而注射相同容量生理盐水的蛋用鸡肺动脉压没有显著变化 (P≥ 0 .0 5 ) ,而且BQ12 3高剂量 (2 .0 μg/kg)对肺动脉收缩压和舒张压的影响比低剂量 (0 .4 μg/kg)的影响大。试验结果说明 ,ETA受体的特异性拮抗剂BQ12 3能不同程度地降低肺动脉收缩压和舒张压 ,推测ET 1是维持蛋用鸡正常肺动脉压的基本条件之一 ;若ET 1和ETA受体发生变化 ,阻断其生物学作用 ,就能改善蛋用鸡肺血流动力学 相似文献
110.
冠心病猝死心肌mcl-1蛋白检测及其意义 总被引:1,自引:0,他引:1
目的观察冠心病猝死(SCD)心肌mcl-1蛋白产物,探讨其免疫组化检测及其对SCD诊断的意义。方法运用免疫组织化学SABC法,对46例SCD和40例非猝死心肌(有冠心病和无冠心病)中mcl-1蛋白产物进行检测和观察,并比较其差异。结果(1)自症状出现至死亡,时间超过30min的SCD(36例),其心肌组织均出现mcl-1蛋白阳性染色;(2)自症状出现至死亡,时间短于30min的SCD(10例),其心肌组织mcl-1蛋白呈弱阳性染色;(3)冠心病非猝死样本(20例),4例心肌出现微弱的mcl-1蛋白阳性染色,无冠心病非猝死样本(20例)几乎没有出现阳性染色。结论心肌mcl-1蛋白的免疫组化检测可诊断自症状出现至死亡时间超过30min的SCD。 相似文献