数字签名与电子签名法

《中华人民共和国电子签名法》已经开始实施,本文对电子签名的定义、使用的范围及其作用作了介绍,并对电子签名技术实现中的一些技术问题如公钥基础设施PKI的功能,三种最常用的公钥算法,数据摘要与哈希(Hash)函数的作用与要求,常用的哈希算法MD5与SHA-1,以及数字签名的技术实现过程作了一些探索。     

中国高水平参与DEPA的关键领域与路径选择

申请加入DEPA不仅是中国主动参与全球数字治理的“先手棋”,更是深化国内改革和高水平开放的关键决策,有助于中国加快构建新发展格局。为推动数字经济由产业创新驱动转向更多依赖技术创新、制度创新驱动的新阶段,中国可重点在数据流动、数字技术、数字产品、数字创新和网络安全五大领域主动对接DEPA协定要求;进一步地,系统化构建以数字自由贸易港为核心,以数字营商环境示范区为抓手、以数字经济产业先行区为重点、以数字经济国际合作区为纽带、以数字经济创新试验区为动能的“一港四区”格局,推动中国数字经济开放发展、创新发展。     

数字经济下的生产社会化与企业分工协作:演进与特性

数字经济是以数字化原料为劳动对象,利用数字化劳动资料进行生产活动的经济形式,在此基础上,数字技术经由企业分工协作体系的重塑推动着生产社会化的发展。依据马克思主义政治经济学原理,以企业分工协作为切入点,通过剖析企业间网络化分工协作和企业内部数字劳动过程,可发现并阐明数字经济下生产社会化中的最新进展及其双刃剑特性。该性质表明:数字经济既可以推动生产活动向社会化方向发展而代表更先进生产力,同时也会激化企业分工与社会分工、生产社会化与生产资料私人占有之间的矛盾。由此表明,数字经济下的生产社会化演进必将呈现出企业分工代替社会分工,以及所有制形式由生产资料私有制向公有制形式转变的发展趋势。     

Analysis of sensitivity and specificity: precise recognition of neutrophils during regeneration of contused skeletal muscle in rats

In this report, we applied the TissueFAXS 200 digital pathological analysis system to rapidly and accurately identify neutrophils during regeneration of contused skeletal muscle, and to provide information for follow-up studies on neutrophils to estimate wound age. Rat injury model was established, and skeletal muscle samples were obtained from the control group and contusion groups at 1, 1.5, 2, 3, 4, and 6 h, as well as at 1, 3, 5, and 15 d post-injury (n = 5 per group). The expression of nuclei and neutrophils was detected by hematoxylin and eosin (HE) staining and immunohistochemical (IHC) staining. A total of 20 injury site areas of 0.25 mm² (0.5 mm × 0.5 mm) were then randomly selected at all time points. A TissueFAXS 200 digital pathological analysis system was used to identify the positive and negative numbers. Knowledge of five professional medical workers were considered the gold standard to measure the false positive rate (FPR), false negative rate (FNR), sensitivity, specificity, and area under the curve (AUC) of receiver operating characteristic (ROC) curves. As a result, with a staining area of neutrophils from 8 µm² to 15 µm², the FPR was 4.28%–12.14%, the FNR was 12.42%–64.08%, the sensitivity was 35.92%–87.58%, the specificity was 87.86%–95.72%, the Youden index was 0.316–0.754, the accuracy was 82.80%–88.30%, and the AUC was 0.771–0.826. The AUC was largest when the cut-off value of the staining area was 12 µm². Our results show that this software-based method is more accurate than the human eye in evaluating neutrophil infiltration. Based on the sensitivity and specificity, neutrophils can be accurately identified during regeneration of contused skeletal muscle. The TissueFAXS 200 digital pathological analysis system can also be used to optimize conditions for different cell types under various injury conditions to determine the optimal cut-off value of the staining area and provide optimal conditions for further study. Furthermore, it will provide evidence for forensic pathology cases.     

国外数字政府研究二十年:热点聚类、演进脉络和发展趋势——基于Cite Space的可视化分析

本文以Web of Science核心文集库2001-2021年发表的353篇关于数字政府研究的文章为样本,运用Cite Space知识可视化软件,通过关键词共现图谱、关键词聚类图谱、演化路径知识图谱和关键词分析,总结了国外数字政府研究概况、国外数字政府研究热点聚类及其发展脉络。研究发现,从2001年起,国外数字政府经历了技术规制、智慧赋能和价值塑造三个阶段,包括十个重要研究聚类,可被分为知识促进、科技支撑、价值培养和合作体系四大主要研究内容。随着数字时代的新要求,数字科技革新和建设路径优化、公共数字伦理和数字素养提升、国家数字主权和公民数字保护预计将成为数字政府研究的热点问题。     

区块链经济学的形成与展望

数字经济是中国经济的重要发展方向之一，而区块链是数字经济的基础技术之一。自2008年以来，区块链的技术取得了长足发展，并且在加密货币、金融、供应链管理、企业管理和公共管理等众多领域产生了广泛的应用前景。文章介绍了最近几年来关于区块链的经济学和金融学研究。首先，文章介绍了区块链的发展背景。其次，文章介绍了区块链的运行机制以及背后的经济学原理。再次，文章从博弈论、市场均衡、网络经济学、交易成本经济学、信息经济学和产业组织理论等多个角度，系统地梳理了关于区块链的经济学和金融学研究成果。最后，文章基于我国区块链产业的发展需求，提出区块链经济学的下一步发展，应该重点关注联盟链落地机制、参与方信息结构、主权货币实施方案以及区块链在医疗、公益、食品安全等行业的具体应用机制设计等问题。     

Is the genie out of the bottle? Digital platforms and the future of clinical trials

Is it possible to conduct impartial clinical trials in a world full of digital networking tools that patients can use to coordinate themselves and act against research protocols? This paper builds on an ethnography of PatientsLikeMe, a company running an internet social media network where patients with different conditions share their clinical data with standardized questionnaires. The company faced a serious dilemma in 2011 when some ALS patients, members of the site, started sharing data about a phase II clinical trial of an experimental drug (NP001) in which some of them were participating, to anticipate the experiment’s outcomes and understand each one’s allocation over trial arms. In parallel, some other patients were using the site and other web tools to coordinate and run their own replication of the trial with homebrew mixes of industrial grade chemicals. PatientsLikeMe researchers reflected on their position as networks managers and eventually decided to use the collected data to develop their own analysis of the efficacy of the original compound, and of the homebrewers’ compound. They presented the NP001 events as a case in point for articulating a new social contract for clinical research. This paper analyses these events, first, by understanding the clinical trial as an experiment organization form that can succeed only as long as its protocol can be enforced; second, we observe how web networks make it dramatically easier for the trial protocol to be violated; finally, we point out how a potentially dangerous confluence of interests over web networks could incubate developments that disrupt the status quo without creating a robust and safe alternative for experimentation. We conclude by warning about the interests of the pharmaceutical industry in exploiting patients’ methodological requests to its own advantage.     

新就业形态的不确定性：平台资本空间中的数字劳动及其反思

在数字技术迅猛发展的影响下，以信息通信技术为支撑的灵活就业形态应运而生，平台资本空间中的数字劳动就是新就业形态的具体表征之一。它的一些共性特征表现为：灵活的时空安排与严苛的多重控制、情感的货币化与制式化的情感、低门槛与去劳动技能化、泛雇佣关系化与去劳动关系化。平台数字劳动在缓解劳动力市场矛盾和传播公共价值方面产生了影响，并且正在推动劳动法规与劳动保障制度的升级。尽管有许多积极因素，但新就业形态的涌现也裹挟着诸多不确定性，主要体现为劳动者职业身份与发展的不确定性、数字治理和劳动保护的不确定性、数字劳动研究范式与方法论的不确定性。这些都值得我们警惕。     

Value-Added Tax (VAT) Development and Reform History—A Study of VAT Evolution Around the World and in China

Value-added Tax (VAT), a turnover tax levied on the value appreciated in commodities production, circulation and sale, has been widely practiced by economies worldwide for its neutrality. From the international perspective, European Union VAT and New Zealand VAT stand out as characteristic models of VAT development and reform history. With changing economic development models and the growth of e-commerce businesses, VAT systems have been upgraded to meet taxation challenges brought about by the digital economy. Recently, VAT policies and measures have been introduced particularly to combat the COVID-19 impact. In China, the VAT system has been reformed constantly over the past 40 years and has been converging with international practice. China now needs to address emerging VAT issues through legislation, tax incentives, and tax-rate grades so as to meet challenges in VAT collection and management and to suit the “new normal” of economic development.     

数码相片的证据作用探析

数码相机在公安司法工作中的应用非常广泛,用数码相机所获取的数码相片,因其的易修改性,使人们对其证据作用产生了怀疑,笔者认为,依据我国法律,数码照片可以作为证据使用,但必须经严格的审查判断。