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951.
952.
体液中常见滥用药物的系统筛选分析 总被引:6,自引:1,他引:5
本文建立了体液中常见滥用药物的筛选分析体系.尿液或血液经固相萃取(SPE)或液提取(LLE)后,直接用GC/NPD分析或经TFA、BSTFA衍生化后用GC/MS分析.方法适用于同时分析甲基苯丙胺、MDMA、度冷丁、去甲度冷丁、曲马多、美沙酮、EDDP、可卡因、苯甲酰芽子碱、可待因、安定、氯丙嗪、吗啡、单乙酰吗啡等十四种常见滥用药物及代谢物.SPE法和LLE法回收率分别为66~102%和50~86%,最低检出限为2-5ng/ml尿.涉毒案件的鉴定应用表明该分析方法简便、快速、可靠. 相似文献
953.
Patrick A. Langan 《Journal of Quantitative Criminology》2001,17(3):273-290
In criminological studies of racial disparities the effect of race on outcomes is assessed after statistical controls for other variables. There is no universally accepted measure of size of disparity after controls in the most common type of disparity study: the study of binary outcomes. Some such studies use a measure that lends itself to interpretation in terms of the proportional reduction in error (PRE). Most use a non-PRE measure of association. This study investigates the effect of choice of measure on conclusions about the size of a disparity after controls. For illustrative purposes the study analyzes data on the awarding of sentence reductions to drug traffickers. After controls, blacks are found to be substantially less likely than whites to receive a reduction according to a type of non-PRE measure: an odds ratio derived from a logit model. But using the same data and model, PRE measures obtained from an ROC analysis indicate that, after controls, there is hardly any difference between the races in their likelihood of sentence reduction. Results illustrate the study's thesis: that the choice of measure can powerfully affect conclusions. The findings' implications—for policymakers and for researchers who conduct racial disparity studies—are discussed. 相似文献
954.
This paper advances a hybrid police cost function that synthesises the proactive/preventive and response/reactive methodologies from the criminology literature. The model presents a coherent estimation process that can help in the allocation of scarce resources to police forces and also enable economists, government organisations and criminologists to assess the scale and technical efficiency of forces. This hybrid model uses response survey data for a sample of English and Welsh police forces in which relative efficiency rankings are contrasted with relative performance measures produced by the Audit Commission. We find that there are considerable divergences in police force's scale and technical efficiency during 1997/98 and 1998/99 utilising non-parametric techniques. 相似文献
955.
Michael Faure 《European Journal of Law and Economics》2001,11(3):207-248
In this paper some studies with respect to empirical socio-economic research which has been undertaken in Belgium and the Netherlands concerning the functioning of legal rules and institutions are discussed. The paper focuses on the domains of criminal law, civil procedure, liability and insurance. The paper argues that contrary to the overwhelming economic literature on liability and insurance, the empirical results in that domain are poor. More research is undertaken in the area of criminal law and apparently it is overwhelming in the area of civil procedure. The latter studies are, however, mainly undertaken by socio-legal scholars and less by economists. The general conclusion of the empirical studies discussed seems to be that while the empirical literature on the effect of changes in the decision making environment on rational actions in the legal system is rich and provocative, there is much less empirical testing of the effects of legal rules as such on allocational outcomes. The paper argues that much more effort should be devoted to the latter issue. 相似文献
956.
Being a victim of sexual aggression from a peer is a common experience among adolescents and poses a significant risk for
various forms of psychopathology. Unfortunately, little is known concerning specific interpersonal factors that increase an
adolescent’s risk for experiencing sexual aggression. The current study assessed the contribution made by several interpersonal
factors both for the first and repeated experience of becoming a victim of sexual aggression from a peer. Data were collected
annually from a longitudinal sample of 200 adolescents over a period of 4 years and were analyzed using multiple-spell, discrete-time
survival analysis. Approximately 46% of the adolescents reported experiencing some form of sexual aggression by the end of
wave 4. Further, 65% of victims reported experiencing a repeat incident of aggression. Females were at higher risk both for
initial and repeated victimization, as were adolescents with more sexual experience and higher levels of rejection sensitivity.
Results are discussed in terms of implications for future prevention efforts.
相似文献
Wyndol FurmanEmail: |
957.
Stuart Shapiro 《Policy Sciences》2008,41(1):33-49
The notice and comment rulemaking process is a fundamental part of how agencies write regulations. While this process is starting
to receive more empirical attention, the question of how the number of comments that an agency receives affects its decision-making
process has received little examination. This paper uses Boolean analysis to examine nine rules from two agencies at the Department
of Health and Human Services and evaluates the impact of a high volume of comments on agency changes to proposed rules and
the time an agency takes to finalize a proposed rule. These nine cases suggest that agencies are most likely to change their
proposals when they receive a high volume of comments on highly complex rules that are not very politically salient. Highly
complex rules are also likely to take a long time to finalize when there are many public comments however it is often other
factors that cause a long delay between proposed and final rules.
相似文献
Stuart ShapiroEmail: |
958.
试论我国传统孝道的现代涵义 总被引:1,自引:0,他引:1
杨彦辉 《河北省社会主义学院学报》2001,(2):59-61
“孝”是中华民族的传统美德,如何继承和发扬传统“孝道”是中国现代家庭文明建没必须要回答和解决的一大课题。本文通过对我国传统“孝道”的辩证分析,指出“孝”是一个优弊共存的“杂糅体”,既有其适应时代发展的合理性因素,又有其阻碍社会发展的局限性,在当今时代,人们应当树立一种崭新的“孝道”观念、“养亲”、“敬亲”、“谏亲”应是现代“孝”道的主要涵义和内容。 相似文献
960.
目的:探讨冬凌草甲素诱导多药耐药细胞系K562/A02凋亡、逆转耐药性的作用.方法:以不同浓度的冬凌草甲素处理K562/A02及敏感株K562/S细胞,流式细胞仪检测细胞凋亡率,四甲基偶氮唑盐(MTT)比色法检测半数抑制率(IC50),分析冬凌草甲素对两种细胞柔红霉素(DNR)、高三尖杉酯碱(HHT)敏感性的影响,流式细胞仪检测冬凌草甲素对两种细胞内DNR浓度的影响.结果:冬凌草甲素可诱导两种细胞凋亡,两者在各浓度、各时点无显著差异;可显著逆转K562/A02细胞对DNR、HHT的耐药性,提高该细胞内DNR的浓度.结论:冬凌草甲素对K562/A02细胞有诱导凋亡、逆转耐药性的作用,是一种很有希望的抗白血病中药. 相似文献