基于X-射线衍射法检测甲基苯丙胺晶体并推断来源

目的采用X-射线衍射法(XRD)建立一种快速检测甲基苯丙胺晶体并推断其来源的方法。方法对18起案件中的53份甲基苯丙胺样本进行XRD检验。结果通过分析主要特征峰强度比例,可以得到毒品的定性分析结果,以及样本的晶型取向信息;通过分析XRD谱图中毒品的特征峰半峰宽信息可以得到毒品的结晶度;对样本中明显的杂质峰进行比对,即可得到毒品来源信息参考。结论该方法简便快捷、无损样本、无污染,能够快速、准确、高效地分析结晶状毒品,为确定制贩毒集团上下线及涉毒案件串并案提供佐证。     

Medical examiner response to the drug overdose epidemic in King County Washington: “Real-time” surveillance,data science,and applied forensic epidemiology

As the overdose epidemic overwhelmed medicolegal death investigation offices and toxicology laboratories, the King County Medical Examiner's Office responded with “real-time” fatal overdose surveillance to expedite death certification and information dissemination through assembling a team including a dedicated medicolegal death investigator, an information coordinator, and student interns. In-house testing of blood, urine, and drug evidence from scenes was performed using equipment and supplies purchased for surveillance. Collaboration with state laboratories allowed validation. Applied forensic epidemiology accelerated data dissemination. From 2010 to 2022, the epidemic claimed 5815 lives in King County; the last 4 years accounted for 47% of those deaths. After initiating the surveillance project, in-house testing was performed on blood from 2836 decedents, urine from 2807, and 4238 drug evidence items from 1775 death scenes. Time to complete death certificates decreased from weeks to months to hours to days. Overdose-specific information was distributed weekly to a network of law enforcement and public health agencies. As the surveillance project tracked the epidemic, fentanyl and methamphetamine became dominant and were associated with other indicators of social deterioration. In 2022, fentanyl was involved in 68% of 1021 overdose deaths. Homeless deaths increased sixfold; in 2022, 67% of 311 homeless deaths were due to overdose; fentanyl was involved in 49% and methamphetamine in 44%. Homicides increased 250%; in 2021, methamphetamine was positive in 35% of 149 homicides. The results are relevant to the value of rapid surveillance, its impact on standard operations, selection of cases requiring autopsy, and collaboration with other agencies in overdose prevention.     

Compounds identified in an illicit generic Xanax tablet are the result of a failed synthesis of alprazolam

Unintended compounds produced by inexperienced clandestine chemists may present a challenge in laboratories tasked with their identification. In March 2020, an anonymously submitted tablet purchased as a generic form of Xanax was analyzed by Erowid's DrugsData.org . The gas chromatography–mass spectrometry (GC–MS) results publicly released online indicated several unidentified compounds due to a lack of database references at that time. Elucidation by our group indicated the presence of several structurally related compounds that were linked to a failed synthesis of alprazolam. For this case study, a published procedure for the synthesis of alprazolam starting with the chloroacetylation of 2-amino-5-chlorobenzophenone was identified as a potential source of this failure. The procedure was reproduced to identify pitfalls of the methodology and examine its possible link to the illicit tablet. Reaction outcomes were analyzed via GC–MS and compared to the tablet submission data. The major compound in this submission, N-(2-benzoyl-4-chlorophenyl)-2-chloroacetamide, along with several related byproducts were successfully reproduced indicating that the tablet contents potentially stem from a failure to synthesize alprazolam.     

Overview of the seized and examined pharmaceutical in the state of Minas Gerais-Brazil by the Civil Police from 2017 to 2022: A fundamental analysis of the recent impact over the drugs market

This work presents a data survey regarding the qualitative chemical analysis of drugs seized by the Police in the state of Minas Gerais between July 2017 and June 2022, including an evaluation of labeling of 265 samples of anabolic androgenic steroids (AAS) seized in 2020. The Active Pharmaceutical Ingredients (API) present in the samples were identified through chemical analysis and classified by system Anatomical Therapeutic Chemical (ATC) methods. Analysis of the labeling information for 265 samples of AAS followed the guidance of legislation RDC 71 (2009) from ANVISA. For this study 6355 seized pharmaceuticals underwent qualitative chemical analysis that corresponded to 7739 APIs successfully identified and classified. Among the components studied AAS, psychostimulants, anesthetics, and analgesics were the most commonly examined. AAS seized and tested increased by over 100% and for the majority of the samples analyzed were found to not match the labeling on the packaging. In the meantime, anti-obesity drugs presented a prominent increase of 400% from 2020/1 to 2021/2, during covid-19 quarantine. Seized pharmaceuticals and tests can support information in the planning of public health and safety policies.     

Colliding intervention in the spatial management of street-based injecting and drug-related litter within settings of public convenience (UK)

This paper considers the structural production and amplification of tensions surrounding the issue of street-based injecting drug use and drug-related litter (injecting paraphernalia) discarded in public settings. These tensions, it is argued, is a consequence of colliding intervention (policy and practice) brought about by conflicting connections between national/local drug strategy and micro-level forms of governance regarding the spatial management of public space. These colliding interventions have negative consequences upon harm reduction and the formation of enabling environments. The paper draws upon data obtained from a five-year (multi-site) ethnographic study of street-based injecting conducted throughout the south of England during 2006–2011.     

Race,Neighborhood, and Drug Court Graduation

This research examines the possibility that racial disparities in drug court graduation are attributable to individual-level employment or education or to neighborhood-level disadvantage. Individual-level data on 455 drug court clients and neighborhood-level census and police incident data are joined geographically. Drug court graduation is modeled using multilevel logistic regression. In a model with no neighborhood-level indicators, client race, employment, and education all predicted drug court graduation. When neighborhood-level variables are introduced, client-level race drops from significance but employment and education remain significant predictors of graduation. Client race, then, appears to be an indirect indicator of neighborhood disadvantage, while client employment and education remain important individual-level predictors of drug court graduation. These results support further analysis of neighborhood-based barriers to drug court graduation and the development of drug court programming that can address neighborhood-based challenges.     

我国禁毒立法的历史演进（1949—1998）

我国禁毒立法秉承了自晚清以来三次禁毒运动的成果,并且以革命根据地时期禁毒的立法实践为历史渊源。1949年至1978年间,禁毒立法以中国共产党和各级政府的相关政策、文件为主要法律形式,以各大行政区的立法为重心。1979年至1998年间,以“严打”为政策导向,逐渐建立了以刑法为主、行政法与地方立法为辅的禁毒立法体系,主要法律形式有刑事法律、行政法律、行政法规、部门规章及其他规范性文件、“两高”司法文件、批准、签署的反毒国际公约和条约、地方性立法及其他规范性文件、民族自治地方的立法等。1998年以后,禁毒政策和立法都出现了一些新动向。     

贩卖毒品案件言词证据问题探讨

毒品的贩卖是毒品从制造到消费过程的主渠道和中心环节,故贩卖毒品罪是毒品犯罪中涉及范围最广的一种犯罪。证据是案件的生命和灵魂,实践中如何针对贩卖毒品案件言词证据的特点,正确充分地收集、审查、判断贩卖毒品案的言词证据,并依据言词证据定案,成为公诉工作中值得探讨的课题。     

Putting a price on drugs: An economic sociological study of price formation in illegal drug markets

Prices in illegal drug markets are difficult to predict. Based on qualitative interviews with 68 incarcerated drug dealers in Norway, we explore dealers’ perspectives on fair prices and the processes that influence their pricing decisions. Synthesized through economic sociology, we draw on perspectives from traditions as different as behavioral economics and cultural analysis to demonstrate how participants in illicit drug distribution base their pricing decisions on institutional context, social networks, and drug market cultures. We find that dealers take institutional constraints into consideration and search for niches with high earnings and low risks. The use of transactions embedded in social networks promotes a trusting form of governance, which enables strategic network management and expedient distribution but also uncompetitive pricing. Finally, dealers’ pricing decisions are embedded in three different cultures narratives: business, friendship, and street cultural stories, with widely varying implications for prices. Our findings demonstrate how an economic sociology of illicit drug distribution can extend insights from behavioral economics and cultural studies into a coherent criminology of illegal drug markets.