兔悬挂双前肢致死组织中PKC、AchE、HSP70的活性变化

目的观察兔悬挂双前肢致死不同组织中PKC、AchE、HSP70的活性变化,探讨其在死亡机制中的作用。方法家兔双前肢悬挂致死亡,取膈肌、肋间肌、心肌、腓肠肌、大脑、脑干、肝、肾、肺等组织,以勒颈、颅脑损伤和疾病死亡相应组织为对照。采用SP法对上述组织中蛋白激酶C(PKC)、乙酰胆碱酯酶(AchE)和热休克蛋白70(HSP70)进行免疫组化染色,观察其活性,并采用多组独立样本的Kruskal-Wallis秩和检验方法,对结果进行统计学分析。结果膈肌、肋间肌和大脑组织细胞质中PKC免疫组化阳性染色,悬挂组较其它组增强(P0.05);膈肌、肋间肌、心肌、大脑和肝细胞质及肌组织神经束中AchE免疫组化阳性染色,悬挂组较其它组增强(P0.05);大脑、心、肺中HSP70免疫组化阳性染色,悬挂组较其它组增强(P0.05)。结论PKC、AChE、HSP70通过不同机制,在悬挂双上肢体位性窒息死亡中起到一定作用,本文结果可为相关研究及鉴定提供实验依据。     

法律解释：克制抑或能动

近来,实务界一直在高调倡导能动司法或司法能动,从而勾起了理论界对司法能动主义探讨的热情。像往常一样,实务界提出的问题,基本是在感觉的基础上理解能动意义的,没有经过认真的论证。从哲学的意义上看,司法能动是法律解释的本质,然而法治要求法律人应该是理性、克制地能动司法,否则能动就变成了毁坏法治的口号。在司法过程中即使少不了能动也不能忘记根据法律进行思维,不顾法律意义的安全性而任意能动不符合法治的基本要求。     

Fiscal and political determinants of local government involvement in public-private partnership (PPP)

ABSTRACT

In this article, we estimate the main determinants of local government’s engagement in public-private partnership (PPP) projects using logistic panel regression. We use data from 2478 municipalities and cities in Poland from 2009 to 2016. The results show that municipalities with higher levels of indebtedness have a higher probability of opening PPP tenders while local units that are more dependent on central grants or receive more European grants are less engaged in PPP. We also found that the mayors of municipalities and cities with stronger electoral competition engage in PPP with a higher probability. These results are important for discussions on the efficient use of PPP. They show that local government decisions made in conditions of fiscal constraint and political struggle can blur the PPP’s value-for-money aim.     

限制性体位窒息死亡的国内外研究进展

限制性体位窒息是指被限制于某种异常体位,造成了自主呼吸功能的障碍引起的窒息,严重时可引起死亡,属机械性窒息中的特殊类型。从国内外有关案例报道来看,限制性体位窒息死亡可以发生在多种环境、体位下。由于早年限制性体位窒息死亡的案例没有引起足够的重视,其作为一个法医学课题起步较晚。近年来由于发生率猛增,已引起国内外法医学家们的极大关注,并对其发生机理、鉴定标准等方面进行了大量研究,但从研究的成果来看,尚不能形成一些客观的鉴定指标,由此,国外关于限制性体位窒息的研究重点已转向其发生的危险因素评估及如何预防。本文就其死亡机理、危险因素及预防、鉴定标准和展望等方面作一综述。     

Assessing the effectiveness and efficiency of a police service: the analytics of operational reviews

Concerns over rising costs have forced police services to balance increasing fiscal and operational pressures. Discussions of the resources and requirements of police, however, are generally only informed by political expediency and traditional practice. Operational reviews (ORs) can be used to document the demands on police, their capacity to respond, and ways in which they can become more efficient and effective. Drawing on an OR of a major urban Canadian police service, this article provides a broad outline of the components of an OR and the analytics that can be used to answer these key questions.     

Devine intervention? Lessons in systemic retrenchment from Canada’s most generous welfare state

This article tackles the importance of systemic retrenchment in welfare state research by focusing on two core elements neglected in the literature: the civil service and governmental revenues. Saskatchewan has possessed key ingredients associated with generous welfare states: a dominant left-wing party, a supportive bureaucracy and important non-visible fiscal revenues. According to the comparative welfare state literature, this is also an excellent recipe for maintaining a generous welfare state amid attempts, primarily by right-wing governments, to scale it back. Yet, most social indicators in the post-Devine years demonstrate that Saskatchewan can no longer be considered a leading welfare state in Canada. Reforms to the bureaucracy and a host of financial measures resulting in a near default explain why the Devine government was successful in its efforts to disrupt the CCF/NDP social legacy despite the fact that the NDP regained power for 16 years afterwards.     

行为的异质性对税法规制的影响及其缓释思路——一种“能力——行为”的分析范式

税法上的"行为"范畴存在高度的异质性,建构统一的"财税行为"概念较为困难。税法领域,不同主体从事的行为性质各异又相互依存,均产生法效果,并需要接受税法的评价和规范;即便是形式上相同的税法主体,由于能力等因素的差异,外在的行为同样呈现突出的异质性。两个层面的异质性对于税法功能的发挥均产生一定影响,须于制度设计时有的放矢、妥为回应。在完善个人所得税制、藉此发挥分配规制的功能时,即应重视税法上行为的异质性,将纳税人的博弈行为纳入决策依据;区分博弈行为的不同层类,循"能力——行为"逻辑脉络辨证施治;同时关注纳税人之间因能力差异引致的行为分殊,在改进征税模式等核心税制时,俱应强调理论和实践的融通。