评美国反基因歧视法律实践及其启示

为防治基因技术的滥用和基因信息歧视,以《2008年禁止基因信息歧视法》为代表的美国联邦和州立法积极实施干预,以确保所有人雇佣机会平等、享有平等健康保险待遇,全面参与社会生活.美国反基因歧视法内容详尽,既禁止基因信息歧视行为,又兼顾保险公司、雇主的合理要求以及避免可能给第三人及公众带来的风险,使违法行为几乎“无缝隙可钻”,且法律对公立雇主的要求高于私立雇主.美国反基因歧视法律实践,对于我们客观认识和把握平等权,完善相关立法和公共政策,具有一定启迪.     

利用Q-TOFLC/MS建立二级谱图数据库快速检测90种农药的初步研究

目的建立90种农药的数据库（含二级谱图）,以达到快速筛选检验该范围内的未知样品目的。方法优化一种Q-TOF LC/MS分析条件,将90种农药分别依次进行Q-TOF LC/MS-MS二级谱图分析,利用PCDL软件建立数据库。并同时实验了血样中10种不同浓度农药（100ng/mL、500ng/mL）的添加实验,对建库方法进行了验证。结果阳性识别率在80%以上。结论本方法简便灵敏、快速实用。     

The politics of ‘wrongful life’ itself: discursive (mal)practices and Tay-Sachs disease

Abstract

This article examines eight wrongful life/wrongful birth suits filed by parents of children born with Tay-Sachs disease. Their legal claims are analysed in terms of the biopolitics of genetic risk that has emerged in recent decades with a view to arguing that, as health and disease are increasingly understood within a genetics framework, the individual is becoming responsibilized to be proactive and undergo genetic testing. At the same time, this responsibilization is being defined as a kind of entitlement rooted in historically specific ideas about personhood and quality of life. The only option for reconciling this contradiction has been simply to define responsibilization as the individual's right, thereby calling into question the notion of agency in genetic decision-making and revealing that choice in this context is in fact becoming the unfreedom to choose.     

Modified cobalt thiocyanate presumptive color test for ketamine hydrochloride

A new presumptive color test for ketamine hydrochloride is reported. The test is a modification of the cobalt thiocyanate test currently used for cocaine and involves basifying samples rather than acidifying them. The two-step procedure for liquids and three-step procedure for powdered samples are straightforward, definitive, and utilize reagents commonly used in forensic drug analysis. The test works on ketamine hydrochloride in both powder and liquid form and has a sensitivity of c. 1.25 mg. Performing the test with numerous other controlled substances and related chemicals demonstrates the test to be highly selective.     

REPORT FROM THE WINGSPREAD CONFERENCE ON DOMESTIC VIOLENCE AND FAMILY COURTS

In February 2007 the National Council of Juvenile and Family Court Judges and the Association of Family and Conciliation Courts brought together a working group of thirty‐seven experienced practitioners and researchers to identify and explore conceptual and practical tensions that have hampered effective work with families in which domestic violence has been identified or alleged. Five central sets of issues were raised at the conference and are discussed in this report. These include the following: differentiation among families experiencing domestic violence, screening and triage, participation by families in various processes and services, appropriate outcomes for children, and family court roles and resources. The report emphasizes the need for continued multidisciplinary collaboration in order to better serve families affected by domestic violence and it includes an appendix of consensus points as well as suggestions for formation of ongoing work groups.     

基因信息与基因隐私权的保护

基因信息包含了一个人生命的全部秘密，应纳入隐私权的保护范围。基因隐私权的内容包括采样时的知情同意权，基因信息的知晓权，基因信息的保密权，基因信息的利用权。侵犯基因隐私权具有便捷性、隐蔽性、关联性、实质性、长久性等特点。我国立法应确立基因隐私权。侵害基因隐私权应承担相应民事责任。     

河南汉族人群12个Y-STR基因座的遗传多态性

目的调查12个YSTR基因座及其单倍型在河南汉族人群中的遗传多态性分布。方法应用PowerPlexYSystem,系统对河南汉族200名无关男性个体进行检测分析,并统计其群体遗传学参数。结果12个YSTR基因座共检出195种单倍型,其中191种单倍型出现1次,1种出现3次,3种出现2次。累积GD值:0.9988。结论12个YSTR基因座具有较强的个体识别能力,可应用于河南地区个人识别和亲权鉴定。     

Trust,vulnerable populations,and genetic data sharing

Recent policies and proposed regulations, including the Notice of Proposed Rulemaking for the Common Rule and the 2014 NIH Genetic Data Sharing Policy, seek to improve research subject protections. Protections for subjects whose genetic data is shared are critical to reduce risks such as loss of confidentiality, stigma, and discrimination. In the article ‘It depends whose data are being shared: considerations for genomic data sharing policies’, Robinson et al. provide a response to our article, ‘The Growth and Gaps of Genetic Data Sharing Policies’. Robinson et al. highlight the importance of individual and group preferences. In this article, we extend the conversation on models for improving protections which will mitigate consequences for individuals and groups that are vulnerable to stigma and discrimination.     

Science wars—How much risk should soldiers be exposed to in military experimentation?

With the threat of biological war becoming a more and more distinct possibility, there is a growing need for vaccines and cures for diseases. As warfare moves from the battlefield to the laboratory, the military must adapt its tactics in order to preserve national security. At the moment, soldiers consent to the risk associated with combat, but with the changing nature of war, the need may arise for soldiers to put themselves at risk not only through combat, but also through scientific experimentation, in order to produce vaccines or cures and ultimately maintain national security. By allowing soldiers to trade risk on the battlefield with risk in the laboratory, deeper research can be made into diseases and biological agents, and this would therefore lessen the threat of biological war or terrorism.