反相高效液相色谱法同时测定人血清中氯丙嗪与氯扎平的浓度

作者建立了同时测定人血清中氯丙嗪与氯扎平浓度的反相高效液相色谱(RP—HPLC)法。以利眠宁为内标,用环己烷—乙醚(1:1)混合溶剂提取血清中氯丙嗪和氯扎平。高浓度中毒者血清(>1ug/ml)则用乙腈沉淀后直接进行色谱测定。血清中氯丙嗪、氯扎平的方法回收率乎均各为98.5±4.0(SD)%,CV4.2%;99.9±4.1(SD)%,CV4.1%。两药在血清中的最低检测浓度为10ng/ml。本法应用于临床氯丙嗪、氯扎平合用药物的血浓度监测及司法中毒案例的分析,结果满意。     

高职大学生生命价值认知的现状及对策分析

生命是世界存在与发展的基础,是教育的原点,是教育研究之本源所在。该文试图客观地对中国高职院校大学生生命价值认知的现状进行剖析,并由此提出相应的对策与建议。     

Evolution of the content of THC and other major cannabinoids in drug-type cannabis cuttings and seedlings during growth of plants

In Europe, authorities frequently ask forensic laboratories to analyze seized cannabis plants to prove that cultivation was illegal (drug type and not fiber type). This is generally done with mature and flowering plants. However, authorities are often confronted with very young specimens. The aim of our study was to evaluate when the chemotype of cannabis plantlets can be surely determined through analysis of eight major cannabinoids content during growth. Drug-type seedlings and cuttings were cultivated, sampled each week, and analyzed by high-performance liquid chromatography with diode array detection. The chemotype of clones was recognizable at any developmental stage because of high total Δ(9)-tetrahydrocannabinol (THC) concentrations even at the start of the cultivation. Conversely, right after germination seedlings contained a low total THC content, but it increased quickly with plant age up, allowing chemotype determination after 3 weeks. In conclusion, it is not necessary to wait for plants' flowering to identify drug-type cannabis generally cultivated in Europe.     

解读“技术侦查”与“乔装侦查”——以《刑事诉讼法修正案》为中心的规范分析

第十一届全国人民代表大会第五次会议通过了《关于修改<中华人民共和国刑事诉讼法>的决定》(即《刑事诉讼法修正案》),明文规定在《刑事诉讼法》第二编第二章第七节后增加第八节"技术侦查措施"。但是,《刑事诉讼法修正案》在技术侦查措施的立法技术上采取了"概括授权"的方式,即仅笼统规定侦查机关对于危害国家安全犯罪、恐怖活动犯罪、黑社会性质的组织犯罪、重大毒品犯罪或者其他严重危害社会的犯罪案件,根据侦查犯罪的需要,经过严格的批准手续,有权采取技术侦查措施,而并未明确列举可采取的技术侦查措施的具体种类和手段。与此相关,《刑事诉讼法修正案》在"技术侦查措施"这一章节下同时授权公安机关为了查明案情,在必要的时候,经公安机关负责人决定,可以由有关人员隐匿其身份实施侦查,此即"乔装侦查措施"。问题在于,《刑事诉讼法修正案》在乔装侦查措施的立法技术上同样采取了概括授权的方式,除列举性地规定了作为乔装侦查方式之一的"控制下交付"之外,并未在立法上明文列举乔装侦查措施的具体类型和方式,其结果是造成《刑事诉讼法修正案》中"技术侦查措施"、"乔装侦查措施"等基础概念含义不清、相关法条内容模糊,减损了法条的可操作性,威胁到司法的确定性,可能直接或间接地冲击《刑事诉讼法》保障人权和打击犯罪的终极目的。《刑事诉讼法修正案》施行在即,上述基础概念的界定问题不解决,司法实务中将无法正确操作《刑事诉讼法修正案》中与"技术侦查措施"和"乔装侦查措施"相关的程序与制度。因此,应运用法律解释的方法对"技术侦查措施"和"乔装侦查措施"这两个基础性概念进行规范解释,勘定"技术侦查措施"和"乔装侦查措施"的合理内涵与外延。     

A Call for Help?: How Public School Principals’ Subjective Report of Institutional Weakness Relates to Disciplinary Incidents

ABSTRACT

Disciplinary incidents at U.S. public middle- and high-schools are a public policy concern. Although businesses popularly give credence to leaders’ subjective intelligence, principals’ reports of their schools’ strengths and weaknesses are questioned. To determine whether principals’ reports carry legitimacy as indicators of student offenses, the current study utilized a nationally representative survey of principals who reported on their sense of the institution and the number of disciplinary incidents in the past year (N = 1,872; replication cohort, N = 1,833). Findings showed that the more institutional shortcomings a principal endorsed, the higher total number of incidents occurred, even after controlling for institutional strength and several indicators of school crime. These findings have policy and intervention implications for improving student outcomes, and so would be of interest to funding agencies, school administrators, teachers, and parents.     

新时代建设高素质专业化干部队伍简析

习近平总书记指出:坚持和发展中国特色社会主义的关键和基础是培育出更多更优秀的社会主义接班人,是我们在新时代工作的重心,也是促进党和国家发展的百年大计,更是实现中华民族伟大复兴的关键所在。如何选拔使用优秀干部,正确管理使用干部,不断提升干部素养始终是保持党长期执政能力建设和先进性纯洁性的关键,是决胜全面建成小康社会,实现中华民族伟大复兴奋斗目标和推进全面深化改革的组织保障。我们党在不同历史时期对干部管理创造了成功的经验。今天,我们党的历史方位发生深刻转变,执政环境发生深刻变化,在面对“四个考验”和“四个危险”的背景下,建设高素质、专业化干部队伍十分紧迫和极其重要。因此,新时代必须进一步提高干部政治素质、政德修养、专业能力,强化干部队伍。     

Conclusion: Mental health and legal responses to the adolescent mental health crisis: Raising the bar on best interests and promoting family connectedness in divorcing families

We are currently facing an unprecedented increase in adolescent mental health problems resulting in alarmingly high levels of depression, anxiety, and suicidality. Significant mental health problems among youth pose unique challenges to families in the process of separation and divorce, as well as to family law professionals across all disciplines. The current adolescent mental health crisis calls for new ways of approaching our work with high conflict families to promote family connectedness and shift away from adversarial approaches that may exacerbate conflict and further destabilize families. As a conclusion to the special issue on adolescent mental health needs, the authors make multidisciplinary best practices recommendations and advocate for systems level changes in recognition of the needs of youth in crisis at this pivotal developmental stage.     

The expanding role of expert psychological evaluations and testimony in Hague child abduction litigation

Hague Convention cases are a growing niche in forensic assessments. These cases focus on returning children, or preventing their return, after international abductions, by one of the parents, has occurred. This article focuses on the legal underpinnings of the Hague Abduction Convention, the “affirmative defenses” that may be invoked to prevent a return order, including “grave risk of harm,” “mature objection”, and the “well settled defense.” The article will also focus on the increasing roles that forensic evaluators play in these matters, the distinction between the role of forensic experts in custody proceedings and Hague cases, and the inherent limitations present in these unique kinds of evaluations.     

Desistance and Legitimacy: The Impact of Offender Notification Meetings on Recidivism among High Risk Offenders

Legitimacy-based approaches to crime prevention assume that individuals will comply with the law when they believe that the law and its agents are legitimate and act in ways that are “fair” and “just.” Currently, legitimacy-based programs are shown to lower aggregate levels of crime; yet, no study has investigated whether such programs influence individual offending. Using quasi-experimental design and survival analyses, this study evaluates the effectiveness of one such program—Chicago’s Project Safe Neighborhoods’ (PSN) Offender Notification Forums—at reducing individual recidivism among a population of returning prisoners. Results suggest that involvement in PSN significantly reduces the risk of subsequent incarceration and is associated with significantly longer intervals that offenders remain on the street and out of prison. As the first study to provide individual-level evidence promoting legitimacy-based interventions on patterns of individual offending, out study suggests these interventions can and do reduce rates of recidivism.     

反相HPLC法同时测定大麻植物中的三种有效成分

目的建立同时测定大麻植物中四氢大麻酚(tetrahydrocannabinol,THC)、大麻二酚(cannabidiol,CBD)和大麻酚(cannabinol,CBN)三种有效成分的高效液相色谱(HPLC)法。方法采用通用C_(18)色谱柱,以乙腈-磷酸盐缓冲液(0.015 mol/L KH_2PO_4)为流动相,流速为1.0 m L/min,检测波长为220 nm,同时收集波长190~400nm的紫外光谱图,并以此光谱图及保留时间作为定性依据。结果所建方法能良好地分离THC、CBD和CBN,三种成分在0.4~40μg/m L范围内线性关系良好(R~2≥0.999 3),回收率大于87%,最低检出限分别为1.8、2.0和1.3 ng,日内精密度与日间精密度均小于5%。结论反相HPLC法简便、快速、准确,适用于大麻植物中THC、CBD和CBN的定性定量检测。