Single primer extension (SPEX) amplification to accurately genotype highly damaged DNA templates

High levels of non-authentic sequence data can be generated by traditional PCR-based methodologies when DNA is damaged, template numbers are small and/or the target amplification size too large. We therefore present an alternate methodology based on single primer extension (SPEX) amplification; that places no pre-defined size constraints on amplification and interacts with only one of the DNA strands at the target locus.     

论网络隐私权保护的现实困境及决策应对

随着《侵权责任法》被列为2009年重点立法项目,网络隐私权保护的问题再次摆在了立法者的面前。有效保护公民的网络隐私权,需要法律法规、主管部门规定、伦理道德等外在因素予以支持,同时也需要网络用户和网络服务提供者等网络活动参与者的配合。针对保护网络隐私权遭遇的现实困境,我国保护措施的不足,应从侵权责任主体出发,从他律、道德内化以及自律三方面进行突破,寻求解决路径。     

法医线粒体DNA检测的系统效能及应用价值

线粒体DNA（mitochondrial DNA，mtDNA）遗传标记的检测在法医学实践中有着重要的价值。线粒体DNA异质性的出现，对检测体系的系统效能存在着影响，主要表现在对所检测样本的单倍型的认同及个体识别概率的计算上。通过建立mtDNA数据库，找出异质性在人群中的发生频率，并使检测异质性的方法标准化．对线粒体DNA的更有效检测具有重要意义；线粒体DNA编码区多态性位点在提高线粒体DNA系统效能中具有独到之处。因此，更进一步地进行mtDNA编码区多态性的探索．将进一步提高线粒体DNA检测的系统效能。     

民法上的人与物——对我国物权立法的考察

我国的物权法已经出台,为了使物权法更有生命力,更好地促进人的生存与发展,对既有的物权法的相关规定保持必要的反思与批判也是物权的人文精神的应有之义。因此,本文试图从物权的人文向度、物权立法的人文解读以及现行物权法的人文检讨等方面对此展开讨论。     

论技术的反生态性及其出路

在严重的生态危机背景下，技术的反生态性致使其常常被指责为生态危机的罪魁祸首。技术的反生态性，不仅仅存在于技术本身，更深层的原因应在于其背后价值观的指导和人性伦理的反生态性。我们该如何运用技术？显然应以遵循大自然为总则，分别从技术选择、科学价值指导和人性伦理的复归三个方面着手回归自然。在我国，科学发展观的指导，技术内部评审机制和外部支撑机制的呼应，为技术生态化的制度性建构描绘了一幅蓝图。     

Personality,socioeconomics and crime: An international comparison

Abstract

Data from 37 countries were collected that permitted exploratory analysis of national profiles in terms of personality dimensions: psychoticism (P); extraversion (E); and neuroticism (N) and four socioeconomic indices: gross domestic product (GDP); human development index (HDI); economic growth (EG); and family size (FS) and their relationship to rates of criminal activity. Findings indicated that the socioeconomic indicators did correlate with national crime patterns. High crime nations were more likely to be the richer, industrialised countries having smalles average family size. Personality variables proved more elusive. P surprisingly was not correlated with incidence of crime rather E appeared mast closely linked to rate and type of crime. Findings are discussed in terms of measurement error and possible explanatory mechanisms.     

刑事救济法律监督机制的构建

在实现刑事司法公正的过程中，救济程序扮演着重要角色，科学严密的救济程序作为刑事诉讼活动的有机组成，能够有效地预防和纠正冤、假、错案。无监督则无公正，刑事救济同样需要检察机关的监督。对包括审前程序在内的刑事诉讼活动全过程中存在的刑事救济程序进行研究，查找存在的突出问题，结合域外相关理论、实践特别是我国检察机关法律监督的具体情况，提出改革我国刑事救济法律监督程序的基本构想，为刑事司法救济程序的研究以及实践打下良好的基础，通过检察机关法律监督的视角阐明检察机关对刑事救济法律监督的具体对策措施。     

欧洲人性论史辨析

人性是人所共有的区别于其他动物的特质和属性.它既与神性、兽性、物性等相区别,又与非人性、反人性等相对立.人性并非是一个超历史、超时空的先验的本质,或是一成不变的抽象存在物,它始终是在人类社会实践活动过程中生成、展现和变化的.人性要素论是人性构成的理论形态,也是人区别于一般动物的心理特质.人性价值论是关于对人性内在本质善与恶、好与坏、美与丑的评价性的理论.人性不仅是哲学的一个基本理论问题,而且也是心理学、生物学和社会学研究的一个主要课题.     

浅析口供获取中的人权保障

在司法实践中,刑讯逼供、超期羁押等严重侵犯犯罪嫌疑人权益的违法现象屡禁不止,导致了不少冤假错案的发生,违背了构建和谐社会的基本要求。新刑事诉讼法的修改和施行,在严格规范了获取口供的同时,突出保障犯罪嫌疑人的权益。但在追求两者统一的目标过程中,依然存在着讯问观念、手段等固化的问题。因此,继续深探问题的根源,从转变诉讼观念和完善立法两个方面入手,剖析如何加强口供获取中的人权保障具有重要的现实意义。     

Following the transfer of DNA: How far can it go?

The issue of DNA transfer is becoming increasingly important in crime scene situations, as DNA analytical techniques now detect tiny amounts. Whereas primary and secondary DNA transfers have been well studied, subsequent transfer steps have received much less focus. This study aimed to measure the detectability of a DNA source after multiple transfer events. Transfer of wet blood gave a full genetic profile well beyond the secondary transfer events on both cotton and glass substrates. Dry blood gave a full profile well beyond the secondary transfer events on glass only, but to a lesser extent than wet blood. Touch DNA only produced a full profile on the primary substrate on both cotton and glass, and detectable quantities beyond the secondary transfer event on glass only. Our results will contribute to a better understanding of the tertiary and subsequent transfer of DNA, which will allow for improved evaluation of the likelihood of alternative scenarios explaining why an individual's DNA was found at a crime scene.