昆明地区复方地芬诺酯片滥用情况分析

目的:了解昆明地区复方地芬诺酯片的滥用情况。方法:自行设计调查表,对2006年1月-2006年5月入所发现的复方地芬诺酯片滥用者进行调查。结果:在2152例海洛因滥用者中共发现复方地芬诺酯片滥用者208例,占9.67%。在208例复方地芬诺酯片滥用者中,男162例,占77.88%,女46例,占22.12%;年龄17-50(33.5±s6.2)a;婚姻状况:未婚134例,占64.42%,同居24例,占11.54%,已婚29例,占13.94%,离异21例,占10.10%;文化程度:小学84例,占40.38%,初中105例,占50.48%,高中及以上19例,占9.13%;职业:无业174例,占83.65%,个体15例,占7.21%,驾驶员8例,占3.85%,服务人员5例,占2.40%,其他6例,占2.88%。滥用复方地芬诺酯片的主要方式:口服(100%);初始滥用的主要原因:"戒毒"(49.04%),目前滥用的主要原因:"替代海洛因"(46.63%);主要来源:药店(83.66%)和小诊所(47.52%);有19例(9.13%)曾发生过滥用复方地芬诺酯片急性中毒。结论:昆明地区药物滥用者中出现复方地芬诺酯片滥用情况;复方地芬诺酯片容易获得;滥用的主要原因与海洛因滥用有关;希望有关部门予以重视。     

影响美沙酮维持治疗效果的相关因素分析

目的:探讨影响美沙酮维持治疗时间及效果的相关因素。方法:研究对象为329名在我院美沙酮维持门诊治疗的海洛因依赖者。根据其在维持治疗门诊中服药时间的长短分为4组。Ⅰ组为服药时间不足3个月退出治疗者124人;Ⅱ组为服药时间超过3个月但不足6个月治疗者52人;Ⅲ组为服药时间超过6个月,但不足1a治疗者76人;Ⅳ组为服药时间超过1a治疗者77人。比较4组海洛因依赖者间的社会人口学特征、药物依赖及治疗剂量等影响美沙酮维持治疗等因素的差别。结果:Ⅱ组、Ⅲ组、Ⅳ组与Ⅰ组相比较,文化程度、职业、婚姻、社会支持系统差异均有统计学意义(P<0.05或P<0.01);Ⅱ组、Ⅳ组与Ⅰ组、Ⅱ组年龄相比较差异有统计学意义(P<0.01);Ⅱ组、Ⅲ组、Ⅳ组与Ⅰ组比较,初吸年龄、吸毒时间、吸毒频率差异均有统计学意义(P<0.05或P<0.01);吸毒方式(单纯注射)、多药物滥用的Ⅱ组、Ⅲ组、Ⅳ组与Ⅰ组、Ⅱ组比较,有非常显著性差异(P<0.05或P<0.01)。首次吸毒原因各组间无差异(P>0.05),既往脱毒次数Ⅲ组、Ⅳ组与Ⅰ组比较差异均有统计学意义(P<0.01)。服用美沙酮剂量与维持治疗时间呈高度正相关(P<0.01),药物剂量、治疗期间服药不稳定的Ⅰ组与Ⅱ组比较,P<0.05;Ⅰ组与Ⅲ组、Ⅳ组比较,P<0.01,差异均有统计学意义。结论:年轻的单身、无业、文化程度低、无家人支持、多药物滥用和维持剂量不足是影响美沙酮维持治疗依从性的危险因素。临床上对影响维持治疗的危险因素进行甄别,并采取相应的干预措施,能有效提高美沙酮维持治疗效果。     

我国药物滥用文献计量学研究

目的:了解我国近10a来药物滥用研究的文献状况。方法:采用"物质相关性障碍"为主题词,对《中国生物医学文献数据库》1997年-2006年收录的药物滥用文章进行检索和分析。根据《中国学术期刊综合引证报告》(2007版)提供的各项统计指标,对药物滥用领域的核心期刊进行分析。结果:(1)我国药物滥用研究论文的发表呈逐年上升趋势;(2)文献的著者以广东、北京和山东发文量最多,占50.4%;(3)大学的相关研究机构和附属医院发文量较多,占30%,其中北京大学发表最多;(4)药物滥用领域的研究中9.8%是基金资助的,而且基金资助数量也逐年增多;(5)载文量最多的期刊是《中国药物依赖性杂志》,其次是《中国药物滥用防治杂志》。结论:《中国药物依赖性杂志》和《中国药物滥用防治杂志》是药物依赖研究领域最受关注的期刊,具有较高的影响力和学术地位。     

关于预防和处置群体性事件对策的思考

预防和处置群体性事件已经成为首都公安民警的一项重要任务,正确认识和妥善处置群体性事件,切实维护社会稳定,促进社会和谐,是首都公安机关预防和处置群体性事件的关键。     

An Early Community-Based Intervention for the Prevention of Substance Abuse and Other Delinquent Behavior

This paper presents the results of an evaluation of an early intervention, risk-reduction strategy versus a standard intervention approach in the treatment of inner-city youth at high risk of adopting a deviant lifestyle. It examines baseline and 1-year follow-up information provided by 408 youth admitted to 2 community-based Baltimore City Youth Bureaus offering counseling services for neighborhood youth referred for delinquent and other problematic behavior. In the study, one of these bureaus served as the experimental intervention clinic and the other as the control, or standard intervention, clinic. Outcome measures involved substance abuse; sexual activity; contact with juvenile authorities; and delinquent activity, including violence-related activity. Regression analyses of outcome measures revealed significant differential results for delinquent activity, which favored the experimental intervention. Relationships between risk/protective factors and outcome are discussed.     

血管内皮细胞生长因子的研究及应用

血管内皮细胞生长因子(VEGF)是一种特异作用于血管内皮细胞的多功能细胞因子,它促使血管内皮细胞分裂增殖、增生、转移,增加血管通透性并促进新血管生成,参与体内的多种生理、病理过程,在临床医学上已获得较多应用,在法医病理学方面将有广泛的应用前景。     

Social Support: A Mediator between Child Maltreatment and Developmental Outcomes

The purpose of the current study was to investigate the relationship between child maltreatment, social support, and developmental outcomes in first-year college students. Participants were 202 undergraduate students (137 female, 65 male) who completed surveys at two time points: once before entering college and once during their first year of college. It was hypothesized that child maltreatment would predict poorer developmental outcomes in adolescence and early adulthood, but that social support would mediate this relationship. Results indicated that child maltreatment related negatively to developmental outcomes and to perceived social support; adolescent and young adult development related positively to perceived social support. In addition, a mediational model in which social support mediates child maltreatment and developmental outcomes was supported.

我国违法少年的处遇方式及其反思

我国法律对于违法少年的处遇主要包括工读教育、治安处罚、收容教养、劳动教养、收容教育、强制戒毒等方式,从现状来看,这些制度体现出执行主体的行政性、程序的不正当性、目的的惩罚性、依据的违法、违宪性等特点,与当今少年司法的理念背道而驰。改革违法少年的处遇方式,将其纳入少年司法的范畴,成为今后我国完善少年法的重大课题之一。     

对个别教育工作的探索与思考

个别教育工作近年来在监狱教育改造工作有逐步弱化的倾向,传统个别教育的方法不能够得到正确的运用,一些新的个别教育方法更是难以得到推广。个别教育工作必须要有创新和发展,并且要建设完善的个别教育保障制度。     

Willingness to Self-Disclose among Late Adolescent Female Survivors of Childhood Sexual Abuse

The primary aim of this study was to compare the willingness of sexually abused (n = 22) and non–sexually abused (n = 36) late adolescent women to self-disclose both general and sexual information to strangers and intimate partners. Results, based on a sample of college women, indicate that those who were sexually abused in childhood are less likely than nonabused counterparts to be highly disclosing of sexual and general information to intimate partners. Avoiding extensive disclosure of personal information to intimate partners may serve to keep survivors of abuse at a relatively safe distance from their own dysphoric feelings and suggests that mistrust of others is an ongoing issue for this population.