Genetic analysis of 15 STR loci on Chinese Tibetan in Qinghai Province

We report allele frequencies and statistical parameters of 15 short tandem repeats (STR) loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA) determined in 850 unrelated individuals of Chinese Tibetan, an ethnic group residing in Qinghai Province, China. We observed 155 alleles with allele frequencies ranging from 0.0006 to 0.5682. The distribution of these observed genotypes were not significantly different from the expected distribution according to Hardy-Weinberg equilibrium. The forensic parameters from the data showed high values. In conclusion, the 15 STR loci are useful for forensic analysis, paternity tests for Tibetans in the region, and population genetic studies.     

Estimating the Number of Crimes Averted by Incapacitation: An Information Theoretic Approach

This paper presents an information theoretic approach for estimating the number of crimes averted by incapacitation. It first develops models of the criminal history accumulation process of a sample of prison releasees using their official recorded arrest histories prior to incarceration. The models yield individual offending trajectories that are then used to compute the number of crimes these releasees could reasonably have been expected to commit had they not been incarcerated—the counterfactual of interest. The models also afford the opportunity to conduct a limited set of policy simulations. The data reveal a fair amount of variation among individuals both in terms of the number of crimes averted by their incarceration and the responsiveness of these estimates to longer incarceration terms. Estimates were found not to vary substantially across demographic groups defined by offender race, gender, or ethnicity; variations across states and offense types were more pronounced. Implications of the findings and promising avenues for future research are discussed.

Examining Racial Disparities in Drug Arrests

The War on Drugs popularized a set of policies and practices that dramatically increased the number of drug arrests, particularly for low-level drug offenses. The War’s tactics have affected Americans of every race; however, minorities have been most dramatically affected. There are several explanations for the observed racial disparity in drug arrests, but relatively little research directly tests these explanations. In this study, we test three common explanations of racial disparities in drug arrest rates. We find that racial disparities in drug arrests cannot be explained by differences in drug offending, nondrug offending, or residing in the kinds of neighborhoods likely to have heavy police emphasis on drug offending. Our findings are most consistent with explanations focusing on racial bias in drug sanctions.     

Identifiler^TM系统在亲子鉴定中的突变观察和分析

目的观察和分析IdentifilerTM系统15个短串联重复序列(STR)位点在亲子鉴定中的突变现象。方法用IdentifilerTM试剂盒检测2712例亲子鉴定案例。结果在2362例认定亲子关系的案例中,观察到51例中有1个STR位点发生突变。突变的位点包括D8S1179、D21S11、D7S820、CSF1PO、D3S1358、D13S317、D16S539、D2S1338、D19S433、vWA、D18S51、D5S818和FGA。其中以D21S11位点突变率最高(0.369%);突变的等位基因来自父亲36次,来自母亲7次,无法确定9次。结论STR位点突变是较为常见的现象,采用IdentifilerTM系统进行亲子鉴定,遇到1～2个STR位点不符合遗传规律时,有必要增加突变率低、稳定性好的STR位点进行复核。     

IN AND OUT OF HARM'S WAY: VIOLENT VICTIMIZATION AND THE SOCIAL CAPITAL OF FICTIVE STREET FAMILIES*

Homeless youth establish a variety of relationships with people they meet on the street. These associations generate different levels of the intangible resources of trust, commitment, and reciprocity that contribute to a person's social capital. We argue that the relationships homeless youth describe as “street families” resemble the fictive kin common among people who have limited resources, and that these relationships are a greater source of social capital than are other associations. Social capital may improve access to many valued outcomes, including protections. Regression analyses of violent victimization support our argument, demonstrating that fictive street families keep youth out of harm's way more than do other street associations.     

Personality features of an adolescent female offending population

The incidence of adolescent offending has been shown to be different for young males and females. However, there is a lack of literature concerning adolescent female offenders, and despite research suggesting that personality factors may be linked with antisocial and criminal behaviour in adolescents and young adults; there have been a lack of studies investigating intra-sex personality differences in young female populations. The Millon Adolescent Clinical Inventory, a 160-item self-report personality measure, was administered to 26 non-offending and 28 offending adolescent females. It was found that the offending group was significantly less submissive, less conforming, more forceful, more oppositional and more likely to exhibit borderline personality traits than the control group. The offending group also had higher reported incidences of childhood abuse and family conflict, and were more prone to substance abuse, impulsive actions and suicide ideation. These initial findings suggest that personality differences may well exist between offending and non-offending adolescent females.     

The Battle for Baghdad: Testing Hypotheses About Insurgency From Risk Heterogeneity,Repeat Victimization,and Denial Policing Approaches

The Iraqi Insurgency (2003–2011) has commonly been characterized as demonstrating the tendency for violence to cluster and diffuse at the local level. Recent research has demonstrated that insurgent attacks in Iraq cluster in time and space in a manner similar to that observed for the spread of a disease. The current study employs a variety of approaches common to the scientific study of criminal activities to advance our understanding of the correlates of observed patterns of the incidence and contagion of insurgent attacks. We hypothesize that the precise patterns will vary from one place to another, but that more attacks will occur in areas that are heavily populated, where coalition forces are active, and along road networks. To test these hypotheses, we use a fishnet to build a geographical model of Baghdad that disaggregates the city into more than 3000 grid cell locations. A number of logistic regression models with spatial and temporal lags are employed to explore patterns of local escalation and diffusion. These models demonstrate the validity of arguments under each of three models but suggest, overall, that risk heterogeneity arguments provide the most compelling and consistent account of the location of insurgency. In particular, the results demonstrate that violence is most likely at locations with greater population levels, higher density of roads, and military garrisons.     

Ultrafast STR Separations on Short‐Channel Microfluidic Systems for Forensic Screening and Genotyping

There are situations in which it is important to quickly and positively identify an individual. Examples include suspects detained in the neighborhood of a bombing or terrorist incident, individuals detained attempting to enter or leave the country, and victims of mass disasters. Systems utilized for these purposes must be fast, portable, and easy to maintain. DNA typing methods provide the best biometric information yielding identity, kinship, and geographical origin, but they are not portable and rapid. This study details the development of a portable short‐channel microfluidic device based on a modified Agilent 2100 bioanalyzer for applications in forensic genomics. The system utilizes a denaturing polymer matrix with dual‐channel laser‐induced fluorescence and is capable of producing a genotype in 80 sec. The device was tested for precision and resolution using an allelic ladder created from 6 short tandem repeat (STR) loci and a sex marker (amelogenin). The results demonstrated a precision of 0.09–0.21 bp over the entire size range and resolution values from 2.5 to 4.1 bp. Overall, the results demonstrate the chip provides a portable, rapid, and precise method for screening amplified short tandem repeats and human identification screening.