毛细管电泳技术分析炸药残留物中无机离子

目的　建立炸药残留物中无机离子的毛细管电泳检测方法。方法　运用缓冲溶液使无机离子在毛细管电泳中达到分离 ,采用紫外间接检测法分析。结果　该方法可从爆炸残留物中准确检测出无机阴离子 (Cl- 、SO2 - 4、NO- 2 、NO- 3、ClO- 3和ClO- 4离子 )和无机阳离子 (NH 4、K 、Na 和Mg2 离子 )。结论　操作方法简便快捷 ,检材用量少 ,检测极限可达ng/ml级 ,分析结果满意     

关于干部选人用人机制建设的思考

新时期,要选好人,用好人,建设高素质的干部队伍,必须加强干部作风建设,必须广开进贤之路,形成人才辈出的局面,必须建立和完善科学的选人用人制度,为经济建设和改革开放提供坚强的组织保证.     

从心理迹证观点建构系统化现场勘察模式

本文从犯罪现场为基础,并以环境犯罪学观点,自国外实证研究结果就个人层级(理性选择理论)、社会互动层级(犯罪型态理论)、社会层级(日常活动理论)三种不同层次探讨性侵害加害者的决策模式(decision-making model)、犯罪空间型态(spatial patterns)、作案手法(modus operandi)与...     

我国破产管理人制度解析

我国新《破产法》中的管理人具有独立性、中立性及专业性特征。从理论上分析,管理人地位采用英美的受托人说更为合理。在管理人的选任方面,现行的法院主导下的随机选任模式是可行的,但在采取公开竞争选任方式时,应改采债权人会议选任、法院进行合法性审查后任命的方式。在管理人的职责方面,《破产法》应明确规定第25条在重整程序及和解程序中是否适用的问题,并对有关管理人在重整程序中的监督内容及监督期限的规定进行改进。     

大力培养选拔优秀年轻干部的几点思考

中国共产党要有效地实现自己的领导 ,就必须高度重视培养选拔优秀年轻干部。培养选拔优秀年轻干部 ,必须从干部的实际出发 ,努力寻找、掌握和运用干部成长规律。要在马克思主义指导下 ,着眼于我们正在做的事情、着眼于党和全国人民的共同理想 ,努力实现培养选拔优秀年轻干部工作的新突破。     

"吾能''慎独''否?"——论"慎独"的道德主体规定性

“慎独”是儒家传统的道德修养方法，也是道德修养所达到的一种极高的境界．具有很强的道德主体规定性。“慎独”并非人人皆能做到，只有具有独立的道德意识、积极的自律精神和完整的道德人格。并能始终践行审慎的道德行为的人才能不断超越和完善自我，成为一位“能‘慎独’者”。     

传统德治经验的启示与借鉴

中国古代的德治思想从产生到发展,从萌芽到建立起完整的理论体系,不仅在理论上伴随着历史的脚步不断演进,而且在实践中也得到了广泛推行。尽管中国历史上的德治无论是理论上还是实践上都具有不可克服的历史和阶级的局限性,但对封建统治者具有约束和警示的作用,并在封建制度所能允许的范围内保护了下层民众的利益。同时,客观上对于中华民族注重道德理想,形成礼仪之邦亦产生了积极的作用。研究和借鉴古代德治的经验,有助于当前"以德治国"方略的实施。     

DNA recovery after sequential processing of latent fingerprints on copy paper

Forensic examiners must determine whether both latent fingerprint development and DNA profiling can be performed on the same area of an evidence item and, if only one is possible, which examination offers the best chance for identification. Latent fingerprints can be enhanced by targeting different components of fingerprint residues with sequential chemical treatments. This study investigated the effects of single-reagent and sequential latent fingerprint development processes on downstream DNA analysis to determine the point at which latent fingerprint development should be stopped to allow for DNA recovery. Latent fingerprints deposited on copy paper by one donor were developed using three sequential processes: 1,8-diazafluoren-9-one (DFO) → ninhydrin → physical developer (PD); 1,2-indanedione-zinc (IND-Zn) → ninhydrin → PD; and IND-Zn → ninhydrin → Oil Red O (ORO) → PD. Samples were examined after the addition of each chemical treatment. DNA was collected with cotton swabs, extracted, quantified, and amplified. DNA yields, peak heights, number of alleles obtained, and percentage of DNA profiles eligible for CODIS upload were examined. DNA profiles were obtained with varying degrees of success, depending on the number and type of treatments used for latent fingerprint development. The treatments that were found to be the least harmful to downstream DNA analysis were IND-Zn and IND-Zn/laser, and the most detrimental treatments were DFO, DFO/laser, and PD. In general, as the number of treatments increase, the opportunities for DNA loss or damage also increase, and it is preferable to use fewer treatments when developing latent fingerprints prior to downstream DNA processing.     

先天性离子通道缺陷造成的心源性猝死研究进展

先天遗传引起的心肌细胞离子通道疾病可引起恶性心律失常,导致患者的晕厥、心脏骤停甚至猝死,而在对这些疾病进行病理学死因鉴定时,常因无阳性发现而缺少科学依据。随着现代分子生物学技术的发展,陆续发现了多种可导致离子通道疾病发病的突变基因。本文针对导致此类疾病中较常见的长QT综合征、短QT综合征、Brugada综合征以及儿茶酚胺敏感性多形性室性心动过速等类型,综述相关突变基因的研究进展,以期为相关研究和鉴定提供参考。     

Development of microwave-assisted extraction procedure for organic impurity profiling of seized 3,4-methylenedioxymethamphetamine (MDMA)

Abstract: Organic impurity profiling of seized 3,4‐methylenedioxymethamphetamine (MDMA) tablets aims to link tablets to common production sources. Conventionally, organic impurities are extracted from tablets using a liquid–liquid extraction (LLE) procedure prior to analysis by gas chromatography–mass spectrometry (GC‐MS). In this research, the development of an alternative microwave‐assisted extraction/headspace solid‐phase microextraction (MAE/HS‐SPME) procedure is described. The optimal procedure used phosphate buffer (1 M, pH 8), with an HS‐SPME extraction temperature of 70°C for 40 min, using a divinylbenzene/Carboxen?/polydimethylsiloxane (DVB/CAR/PDMS) fiber. Impurities were extracted from seized MDMA exhibits using the MAE/HS‐SPME procedure, as well as HS‐SPME alone, and a conventional LLE procedure. The HS‐SPME procedure was deemed to be the most practical because of the affordability and need for less analyst involvement. Although the LLE was limited in the number of impurities extracted, the procedure is still useful for the extraction of less volatile impurities that are not extracted by HS‐SPME.