Aviation security and terrorism

Abstract

The author asserts that a sophisticated sabotage threat to U.S. international civil aviation has been well known to the U.S. government and air carriers since the early 1980s. He believes that both the U.S. government and air carriers have failed to do enough to counter this sabotage threat. He cites the findings of the President's Commission on Aviation Security and Terrorism (May 1990), and the enactment of the Aviation Security Improvement Act (Nov. 1990) to support his beliefs. The author concludes by providing a recipe for corrective action.     

A Clinical Trials Recruitment Education Program for Immigrant Chinese Americans

Abstract

This study was designed to develop and evaluate a community-based education program to facilitate enrollment of immigrant Chinese into clinical cancer screening trials. The program included workshops with culturally tailored health education materials. It was piloted to recruit persons into an ongoing lung cancer screening trial from a senior citizen center in Manhattan's Chinatown and compared with a control program at a second senior center. Survey results from a convenience sample of seniors showed that the workshop raised awareness about cancer screening and clinical trials. However, it did not change attitudes towards cancer screening. The results highlighted prior focus group findings in which factors influencing participation in cancer screening and clinical trials are similar. Important facilitative factors include doctor recommendation, friend/family recommendation, the belief that early detection could “save lives,” no cost, and having an-interpreter.     

Screening for Substance Use Disorders as a Supplement to Caseworker Assessment Among Foster Care–Involved Families

Parental substance abuse is a major factor in families experiencing foster care placement, yet little is known about the potential of screening in determining risk or identifying subpopulations for which elevated risk occurs. One Midwestern state recently implemented screening. This research uses information gathered as part of the screen's implementation to conduct a latent class analysis. The research was extended to provide a detailed examination of differences in child and family characteristics across classes, and to compare the screen results with caseworker impressions. Three distinct typologies emerged, with the high-risk and moderate-risk designations comprising only one quarter of the cases.     

Comparative Analysis of the HV1 and HV2 Regions of Human Mitochondrial DNA by Denaturing High-Performance Liquid Chromatography

Abstract:  Denaturing high-performance liquid chromatography (DHPLC) was evaluated as a sequencing-independent means of detecting the presence of sequence differences in pair-wise mixtures of nonconcordant amplicons of human mitochondrial DNA (mtDNA). A total of 920 pair-wise combinations of HV1 and HV2 mtDNA amplicons from 95 individuals were assayed by DHPLC for sequence concordance/nonconcordance. For the 72 combinations of amplicons from different individuals who shared identical DNA sequences, DHPLC assays consistently indicated sequence concordance between the samples. This was in 100% agreement with sequencing data. For the 849 combinations of amplicons which differed in sequence, DHPLC detected the presence of sequence nonconcordance in all but 13 assays to yield 98.5% concordance with sequencing. Thus, DHPLC can be used to detect a diversity of sequence differences (transitions, transversions, insertions, and deletions) in the mtDNA D-loop. Accordingly, DHPLC may have utility as a presumptive indicator of mtDNA sequence concordance samples, as a screen for heteroplasmy/situational mixtures, and as a means for the physical fractionation of the individual contributors to an mtDNA mixture prior to sequencing.     

体液中常见滥用药物的系统筛选分析

本文建立了体液中常见滥用药物的筛选分析体系.尿液或血液经固相萃取(SPE)或液提取(LLE)后,直接用GC/NPD分析或经TFA、BSTFA衍生化后用GC/MS分析.方法适用于同时分析甲基苯丙胺、MDMA、度冷丁、去甲度冷丁、曲马多、美沙酮、EDDP、可卡因、苯甲酰芽子碱、可待因、安定、氯丙嗪、吗啡、单乙酰吗啡等十四种常见滥用药物及代谢物.SPE法和LLE法回收率分别为66～102%和50～86%,最低检出限为2-5ng/ml尿.涉毒案件的鉴定应用表明该分析方法简便、快速、可靠.     

虚假“认罪认罚”之甄别--以经验法则的运用为视角

经验法则是审查核实犯罪嫌疑人、被告人认罪认罚是否真实的不可或缺的依据和方法。司法实务中,运用经验法则判定认罪认罚是否真实时,应当注意防范经验法则的盖然性、丰富性特征潜在的诱发错判的风险,并从认罪认罚的"三性"(即自愿性、真实性和合法性)契入,重点审查核实所引依据是否经验法则、所引经验法则是否与待定事项对应和是否存在例外情形,应高度重视程序合法情形下认罪认罚的真实性审查,避免发生"罪从供定"和忽视收集、审查供述之外的其他证据的情形。     

传染性腔上囊病病毒VP3蛋白模拟表位的筛选

为了研究传染性腔上囊病病毒(IBDV)的致病机理及研制有效的IBDV疫苗,利用噬菌体展示技术对IBDV VP3抗原表位进行了筛选。以4株IBDV VP3单克隆抗体HRB-3F、HRB-7B、HRB-7C和HRB-10E作为筛选分子,对噬菌体随机15肽库进行3轮吸附-洗脱-扩增淘洗,从每株单克隆抗体筛选到的噬菌斑中随机挑取20个单克隆噬菌斑,通过间接ELISA和竞争抑制ELISA检测,共选出13个单克隆噬菌斑,经噬菌体gⅢ部分基因的核苷酸序列测定,确定了8个15肽为IBDV抗原表位。这8个15肽在一级结构上没有3个以上连续氨基酸与IBDV Gx(Gen-Bank登录号:AY444873)VP3的氨基酸序列相同,但二级结构上均以β折叠为主,并且与单抗的结合可被VP3蛋白有效地抑制。证实,筛选的是IBDV VP3的模拟表位。     

论刑法适用中的隐性不平等--以刘海洋案为视角的考察

在我国刑法的适用过程之中存在着隐性不平等问题 ,并且 ,这一问题基本上脱离了学界的研究视野。面对刑法适用之中的隐性不平等问题 ,应当在刑法基本原则的整体框架内理解罪刑平等原则 ,并且要在制度创新和裁判者素养提高的双重规制下抑制刑法适用之中的隐性不平等问题     

罪犯申诉机制探析

根据法律规定,罪犯对已经生效的判决不服可以进行申诉,同时罪犯申诉也为审判监督程序的启动提供了重要材料来源,但是由于我国申诉制度本身存在的一些缺陷和不足,从而导致了罪犯申诉难的问题,这对于罪犯权利的保障以及对其改造效果都造成了不良的影响。因此本文从罪犯申诉着手,对完善我国的申诉制度进行探讨,希望能对我国罪犯申诉权的保障以及申诉制度的完善方面有所帮助。     

产前畸形筛查医疗损害责任之司法鉴定20例分析

目的：研究产前畸形筛查医疗损害责任司法鉴定案件的一般规律及其医疗损害责任司法鉴定的特点,为法医学鉴定提供理论支持。方法：对20例产前畸形筛查医疗损害责任司法鉴定案例进行回顾性分析。结果：产前畸形筛查医疗损害责任司法鉴定案例逐年增多;发生纠纷的医疗机构以市（区）级为多见,发生纠纷的案件中以手足畸形和先心病多见;医疗损害责任司法鉴定的主要原因为医疗技术缺陷与医疗管理缺陷。