It Takes a Village: Using a Community-Defined Practice Approach to Develop a Tribal In-Home Services Model for Alaska Native Families

The current evidence base for in-home services in child welfare is limited, with insufficient research on the use of in-home services among ethnically diverse populations. This article describes a case study examining the use of a community-defined practice and evidence approach to develop tribally based in-home service models with Alaska Native communities. The models were co-created by tribal elders, community members, and service providers, with technical assistance provided by the Western and Pacific Child Welfare Implementation Center (WPIC). Research findings suggest that this is an effective approach to developing culturally appropriate child welfare practices while also building local support and ownership.     

基于PTEN研究桃红四物汤治疗产后血瘀证的机制

目的 观察桃红四物汤对产后血瘀证大鼠子宫第10染色体缺失的碱性磷酸和张力蛋白同源物（phosphatase and tensin homolog deleted in chromosome 10,PTEN）mRNA及其蛋白表达的影响,探讨其祛瘀生新的作用机制。方法 采用米非司酮和米索前列醇灌胃法复制产后血瘀证大鼠模型,将模型大鼠分为模型组,阳性对照组（益母草颗粒4.3 g/kg）,桃红四物汤高剂量（18.0 g/kg）、中剂量（9.0 g/kg）、低剂量（4.5 g/kg）组,另设正常对照组。连续灌胃给药7 d后,麻醉大鼠并分离子宫,光镜下观察子宫血瘀状态,分别采用实时PCR和Western blot法检测子宫组织PTEN mRNA及其蛋白表达水平。结果 桃红四物汤能改善产后血瘀证大鼠子宫间质的充血、水肿。与正常对照组比较,模型组PTEN mRNA及其蛋白表达水平显著升高（P<0.05）;与模型组比较,桃红四物汤高剂量组PTEN mRNA及其蛋白表达水平均显著降低（P<0.05）,桃红四物汤中剂量组仅PTEN蛋白表达水平显著降低（P<0.05）。结论 桃红四物汤的祛瘀生新作用可能与其下调PTEN的表达有关。     

阿维菌素对鸽脑组织GABAA受体结合作用的影响

在试验组日粮中按40 mg/kg添加阿维菌素(AVM),对照组饲喂不添加AVM的常规日粮,利用3H-蝇蕈醇(3H-muscimol)与鸽脑组织γ-氨基丁酸(GABA)均能与GABAA受体结合的特性,应用放射免疫法测得3H-蝇蕈醇与王鸽大脑GABAA受体结合的平衡解离常数(kd)和最大结合量(Bmax)分别为(44.62±2.07)nmol/L和(3.31±0.10)pmol/mg。结果表明,AVM可使3H-muscimol与王鸽大脑组织GABAA受体结合量增大,AVM可促进GABA的释放,增强GABA的抑制作用。     

论刑事侦查中计算机数据的保护

随着计算机、网络犯罪的增多,收集计算机数据类证据成为侦查工作的重要内容。由于这类证据的特性,保护计算机数据成为收集证据的重要环节,而使用扣押措施不能迅速、有效地保护计算机数据,同时可能严重侵犯他人权利。欧洲委员会《关于网络犯罪的公约》中规定了现存计算机数据的快速保护措施,是针对计算机数据进行迅速保护的特殊调查措施,与我国相关的强制网络服务提供者记录和保存信息的规定相比较具有更大的优越性,因此,我国相关立法中应予以借鉴。     

婴幼儿猝死综合征心传导系统的免疫组化研究

作者应用ＰＧＰ９．５与抗Ｓ１００抗体和高压消毒蒸锅抗原复活技术对４例婴幼儿猝死综合征（ＳＩＤＳ）和３例非心源性死亡对照婴儿心传导系统的神经组织总量进行免疫组化研究。结果：在正常婴儿心传导系统，ＰＧＰ９．５与Ｓ１００阳性的神经纤维里不均匀分布，以窦房结最多，房室结次之，希氏束最少；４例ＳＩＤＳ心传导系统的神经组织分布同对照组无明显差异。     

The Italian perspective of the right to oblivion

This paper gives a brief overview of the state of the art relating to the right to oblivion in Italy. Three major issues on the way this right is perceived, recognized and protected are presented. First, the strict link between the right to oblivion and the right to information is discussed. Then, the role of the internet revolution in enlarging the protection to different situations related to the right to oblivion is analyzed. Finally, a reflection on the distinction between the right to oblivion and the right to data protection and specifically from the right to erasure, anonymization or blocking of data that have been processed unlawfully is drafted.     

Model for the prediction of mechanical asphyxia as the cause of death based on four biological indexes in human cardiac tissue

Determination of mechanical asphyxia as the cause of death has always been difficult for forensic pathologists, particularly when signs of asphyxia are not obvious on the body. Currently, depending on only physical examination of corpses, pathologists must be cautious when making cause-of-death appraisals. In a previous study, four biomarkers—dual-specificity phosphatase 1 (DUSP1), potassium voltage-gated channel subfamily J member 2 (KCNJ2), miR-122, and miR-3185—were screened in human cardiac tissue from cadavers that died from mechanical asphyxia compared with those that died from craniocerebral injury, hemorrhagic shock, or other causes. Expression of the markers correlated with death from mechanical asphyxia regardless of age, environmental temperature, and postmortem interval. However, a single biological index is not an accurate basis for the identification of the cause of death. In this study, receiver operating characteristic curves of the ΔCq values of the four indexes were generated. The diagnostic accuracy of the indexes was judged according to their area under the curve (DUSP1: 0.773, KCNJ2: 0.775, miR-122: 0.667, and miR-3185: 0.801). Finally, a nomogram was generated, and single blind experiment was conducted to verify the cause of death of mechanical asphyxia.     

Embedding the Notion of Child- and Family-Centered Care into Organizational Practice: Learning from Organizational Visioning

Child- and family-centered care has permeated the practices of child welfare as a means to address fragmentation. Case management appears promising, but the approach is still in its infancy. This article aims to provides an understanding of the emergent organizational vision of a new approach to case management at multiple organizational levels. The authors conducted a case study on the implementation of Intensive Family Case Management in a Dutch organization that provides child and youth protection services. The focus is on the continuous and bottom-up process of visioning, which has helped to define the shared organizational vision. The key finding was an emerging, widely shared vision that is congruent at many organizational levels and that contrasts starkly with the old work approach. The conclusion is that innovative child- and family-centered approaches to case management are inherent to a multi-level organizational system that is consistent with the approaches it advocates, being embedded in organizational structures and embodied in practitioners’ mindsets.     

Attitudes on the Responsibility for Child Safety: Key Child Protection Worker Characteristics

The child protection workers’ attitude toward responsibility for child safety is complex and requires further examination. Using the Quality Improvement Project on Differential Response data from Illinois we examined the characteristics that influence worker attitude towards child safety. The attitude variable measures workers’ belief in family responsibility for child safety compared to state responsibility for child safety. Regression analyses suggest that self-perception of skills, confidence in community resources, confidence in the child protection system, and worker age significantly predict worker attitude. Findings support organizations to direct resources towards shifting attitudes in the direction that favors agency mandate and needs.     

CT‐Guided,Minimally Invasive,Postmortem Needle Biopsy Using the B‐Rob II Needle‐Positioning Robot

CT‐guided, minimally invasive needle biopsy techniques can be used to retrieve tissue or body fluid samples for histologic tissue diagnoses in forensic investigations. The purpose of this study was an evaluation of CT‐guided needle‐positioning robot B‐Rob II. To operate under CT guidance, we adopted the B‐Rob II robotic needle placement system and its workflow. The accuracy and speed of the procedure were tested on a gelatin phantom in a series of 21 biopsies. We achieved an average needle placement accuracy of 1.8 mm (±1.1 mm) using robotic assistance. The procedure required an average of 2 min 21 s. The needle placement accuracy for minimally invasive needle biopsies using the B‐Rob II biopsy robot is sufficiently accurate and fast for forensic postmortem examinations of focal organ changes. Further tests will be performed to test the feasibility of the robot for performing biopsies of focal organ changes in human bodies.