脑络欣通对大脑中动脉阻塞再灌注模型大鼠神经干细胞增殖分化的影响

目的 观察脑络欣通对大脑中动脉阻塞再灌注（middle cerebral artery occlusion-reperfusion,MCAO-R）模型大鼠神经干细胞增殖分化的影响。方法 采用线栓法复制MCAO-R大鼠模型,将30只健康雄性SD大鼠随机分成假手术组、模型组和给药组。分别采用神经功能评分和TTC染色鉴定模型大鼠的神经功能缺损和脑缺血面积,采用免疫荧光染色法观察大鼠海马CA1、CA2、CA3、齿状回（dentate gyrus,DG）区巢蛋白（Nestin）和神经丝蛋白-H（hypophosphorylated neurofilament-H,NF-H）表达水平。结果 给药组Nestin阳性表达主要发生在DG区,NF-H阳性表达主要发生在CA3区。脑络欣通促进神经干细胞增殖的作用在DG、CA1、CA2、CA3区均十分明显,以DG区尤为突出,促进神经干细胞分化的作用主要表现在CA3、DG、CA2、CA1区。与模型组比较,给药组大鼠海马各区的Nestin、NF-H阳性细胞均明显增多,差异具有统计学意义（P＜0.05）。结论 脑络欣通具有促进海马区神经干细胞增殖并分化为神经细胞的作用。     

针刺联合镜像疗法治疗脑卒中患者上肢运动功能障碍临床疗效观察

目的 观察针刺联合镜像疗法治疗脑卒中患者上肢运动功能障碍的临床疗效。方法 将90例脑卒中上肢运动功能障碍患者按随机数字表法分为对照1组（30例,给予针刺治疗）、对照2组（30例,给予镜像疗法治疗）和观察组（30例,给予针刺联合镜像疗法治疗）,疗程均为2周。比较3组患者治疗前后Fugl-Meyer评估量表上肢板块（Fugl-Meyer assessment upper extremity,FMA-UE）评分,Wolf运动功能测试（Wolf motor function test,WMFT）量表评分,改良Barthel指数（modified Barthel index,MBI）,国际功能、残疾和健康分类（international classification of functioning,disability and health,ICF）评分及伸腕主动运动范围（active range of motion,AROM）和基于FMA-UE评分判定临床疗效。结果 观察组临床疗效优于对照1组和对照2组（P＜0.05）;治疗后3组患者FMA-UE评分、WMFT评分、MBI均较治疗前显著增加（P＜0.05）,ICF评分显著减少（P＜0.05）,且观察组FMA-UE评分、WMFT评分、MBI增加程度,ICF评分减少程度显著大于对照1组和对照2组（P＜0.05）;治疗后观察组患者伸腕AROM显著大于对照1组和对照2组（P＜0.05）。结论 针刺联合镜像疗法能有效改善脑卒中患者上肢运动功能障碍。     

膈肌疲劳在家兔体位窒息死亡中的作用

目的探讨膈肌在固定双上肢悬挂致死中的作用。方法将家兔固定双上肢悬挂,并监测家兔膈肌肌电图(EMGdi)的变化。结果在连续记录的EMGdi中早期的EMGdi与晚期的EMGdi比较高频与低频(H/L)的比值显著降低,提示膈肌疲劳确实存在。结论膈肌疲劳在固定双上肢悬挂致死中起着重要的作用。     

3～6世纪胡人入据岷江上游及对"岷江道"的开拓

岷江上游自古是一条民族迁徙通道,在公元3~6世纪有不少胡人入据这一区域且十分活跃,但目前学术界对岷江上游的胡人活动的史实尚重视不够。本文通过对相关史籍记载的分析,系统梳理了魏晋南北朝时期胡人在岷江上游地区的活动,认为胡人的入据对当时沟通西域与南朝陆路交往的"岷江道"的开拓起了重要作用。     

Iatrogenic tracheal laceration causing asphyxia

Endotracheal intubation is a simple, rapid, and safe technique that is being used as a standard procedure for airway management. However, airway injury during endotracheal intubation could be a significant source of morbidity or even mortality for patients and a source of liability for physicians as well. We report an unusual case of fatal tracheal occlusion by intraluminal blood clot complicating endotracheal intubation. The patient, a 62-year-old woman, with renovascular hypertension and incipient renal failure was scheduled for renal autotransplantation. The surgery was uneventful but the postoperative course was complicated with a lethal airway obstruction. At autopsy a linear longitudinal tracheal laceration was identified with an intraluminal blood clot obstructing the tracheal lumen. Tracheal laceration as a cause of death is a rare and potentially fatal complication of endotracheal intubation with intratracheal bleeding, clot formation, tracheal occlusion, and subsequent asphyxia.     

浅谈洗钱犯罪的侦查难点及对策

洗钱犯罪是我国新时期面临的重大犯罪之一,它具有的隐蔽性、复杂性、专业性,以及与上游犯罪紧密联系的特征等,使该类犯罪的侦查工作面临严峻的困难和挑战。为了保证反洗钱工作的顺利开展,应进一步完善反洗钱的立法工作,加强反洗钱的执法力度,规范金融机构防范洗钱的运行机制。     

对职务犯罪案件审查逮捕程序改革与完善的思考

职务犯罪案件审查决定逮捕权"上提一级",是加强自身监督、规范检察权行使、促进检察工作科学发展的重要内容。改革后取得了强化监督的效果,但也暴露办案期限紧张、附条件逮捕缺乏法律依据、听取律师意见程序有待细化、不服逮捕缺乏救济等问题。因此有必要进行立法建言和制度改进,使改革措施落到实处,在惩治腐败与保障人权间寻求最佳平衡。     

洗钱罪构成要件与立法完善

我国现行《刑法》及《修正案》关于洗钱罪犯罪构成的设计还存在较多缺陷,与我国签署的相关国际公约还不协调,尤其未能把贪污贿赂犯罪纳入洗钱罪的上游犯罪,不利于惩治腐败犯罪,也不利于反洗钱的国际合作。因而,应尽快制定《反洗钱法》,惩治洗钱罪的上游犯罪,完善相关的刑事措施与制度,加强反洗钱国际合作。     

Endobronchial/Tracheal Metastasis and Sudden Death

Endobronchial and endotracheal metastases are rare lesions that may cause acute occlusion of major airways. A case is reported of a 62‐year‐old man with history of renal cell carcinoma and hemoptysis who died after having suddenly become short of breath with cyanosis. At autopsy, recurrent renal cell carcinoma was identified with metastases to the lungs, pulmonary hilar lymph nodes, and brain. In addition, a solitary papillomatous metastasis arising from the mucosa of the carina was obstructing both the main bronchi and distal trachea. Death was due to acute airway obstruction by a metastatic deposit at the bifurcation of the trachea in a case of disseminated renal cell carcinoma. This case demonstrates an extremely rare cause of sudden death that may complicate disseminated malignancy.     

浅析我国地方政府房屋限购令

我国地方政府房屋限购令具有形式多样性,效力双重性、规范性和强制性的特征,在目的上具有现实合理性。应秉承＂取其精华,保留正当政策,去其糟粕,改进调控手段＂的原则,对地方政府房屋限购令的内容加以完善。