李大钊早期传播马克思主义的再探讨

五四前后李大钊通过办报办刊、发表论著、组织社团、办学讲课、演讲辩论等方式向中国民众传播了马克思主义。他早年对马克思主义的研究和宣传主要涵盖了四方面内容：揭露了帝国主义的本质,阐述了十月革命的伟大意义;较系统地论述了马克思主义理论的基本内容;正确论述了中国革命的一些基本问题,如革命的步骤、手段、动力等等;号召学生和知识分子走与工农相结合的道路。这些杰出的思想主张形成了他早年的理论特色。当然,李大钊对马克思主义的最初理解也存在着一些不准确之处,这种认识偏差是与当时他所处的环境和背景分不开的。李大钊的可贵之处在于其思想随着社会的进步不断发展,并及时将先进的科学理论运用于中国社会变革的实践。     

行政许可程序的立法欠缺及其完善

行政许可程序是规范行政许可的行为,防止行政许可实施权的滥用,保障公民、组织在行政许可实施中的正当权利的重要环节。尽管行政许可法设计了许多程序规则,但在某些方面还存在问题,诸如处理期限的规定不完善、听证程序不健全、缺乏有效的保障制度等。笔者在对此分析研究的基础上,提出了一些健全和完善我国行政许可程序的设想和建议。     

A real-time multiplex SNP melting assay to discriminate individuals

A method that quickly and inexpensively differentiates crime scene samples from multiple donors would expedite casework analysis by allowing the selection of probative items requiring comprehensive testing. This new method need not be perfectly definitive nor give a complete 13 locus short tandem repeat (STR) profile; it simply must be able to differentiate between most victim and suspect samples. We describe the development of multiplex, single nucleotide polymorphism (SNP), fluorescence resonance energy transfer-based real-time polymerase chain reaction (PCR) assays to fulfill this need. Dual probes, one fluorescently labeled and the other labeled with a quencher, are monitored during a melt analysis to reveal an increase in fluorescence, which allows the assessment of the two SNP alleles. Two alternate 6-plex assays (with and without gender determination) have been developed for the six-color RG6000 real-time instrument (Corbett Robotics, Inc.) and one seven SNP plus gender assay (performed as two 4-plex assays, one with gender the other without) have been developed for use in four/five color real-time instruments. This technique can discriminate between 95% and 99% of samples from different individuals. This assay is fast (approximately 2 h), much less expensive than STR analysis, and uses a real-time PCR instrument which is found in most forensic and molecular biology labs.     

大鼠弥漫性轴索损伤后NGF表达

目的研究大鼠弥漫性轴索损伤后神经生长因子（NGF）表达的时间变化规律及意义。方法采用SD雄性大鼠复制弥漫性轴索损伤（DAI）模型,分别于伤后1、3、6、12、24、48h和3、7d取脑组织,应用免疫组织化学法对DAI后不同时间段大脑皮层、丘脑、小脑和海马部位NGF的表达变化进行观察并与正常组、假手术组对照。结果正常及假手术组大鼠大脑皮层、丘脑、小脑、海马均有少量NGF的表达。打击后1hNGF表达增强,12h达高峰,3d开始下降,7d降至正常。结论NGF参与弥漫性轴索损伤后的修复：NGF的时序性变化有望成为法医学脑损伤时间推断的客观指标。     

"战略时间差"与中国的战略安全

国际关系中的时间包括时间点、时间段和时间过程。从国际博弈的时间长度来看,既有宏观时间的博弈,也有微观时间的博弈,二者都有可能产生战略性的影响。纵观古今中外历史,把握“战略时间差”虽然不一定能做到“不战而屈人之兵”,但能够做到以更小的代价获得博弈的优势地位。中国的战略安全是与战略机遇期联系在一起的,过去四十多年中国发展和大国成长战略机遇的获得主要由于技术革命、权力转移和西方的战略失误三个因素,但中国在新时代需要主动通过把握和运用“战略时间差”来塑造战略机遇。从总体战略来看,中国仍然需要争取和平的国际环境,以彰显中国在走向世界舞台中央时的世界担当;要尽力争取所有的国际博弈尤其中美博弈为正和博弈,以化解既有主导国对正在崛起的中国的担心和不信任;关键还要着力中国的内部发展,这是获得战略机遇期的实质性内容。把握所有“战略时间差”的最终目标是实现中华民族的伟大复兴,在世界舞台上和平崛起。     

建设一个走在时代前列的执政党

一个先进的政党,只有站在时代的前列,与时俱进地用时代眼光审视自己,才能找准自己的历史坐标,保持旺盛的生机与活力.     

Identifying Unit-Dependency and Time-Specificity in Longitudinal Analysis: A Graphical Methodology

Longitudinal analysis in criminology and other social sciences has become an important research tool because it allows us to draw conclusions from observing how multiple units change over time. Unfortunately, its results are more vulnerable to potential influences of unusual observational units or periods of time. Current leverage diagnostics are designed for cross-sectional analysis and are fallible when applied to longitudinal models. This article introduces a graphical diagnostic methodology to systematically examine the sensitivity of longitudinal results to extreme observational units and periods of time—unit-dependency and time-specificity. Further the article illustrates its use with an example testing policy effects on black and white female victimization of intimate partner homicide. Results are displayed in an easily understood graph that provides a snapshot of the results' time-specific patterns and robustness to unit-dependency. Currently, comparable tests for panel analysis are tedious and cumbersome. With this new illuminating methodology, researchers and policy-makers can easily decide whether a time-specific or unit-dependent pattern is consequential.     

大鼠脑挫伤后GFAP和iNOS表达与损伤时间关系的实验研究

目的　观察大鼠实验性脑挫伤后胶质纤维酸性蛋白 (GFAP)和诱导型—氧化氮合成酶 (iNOS)的表达及其时相性的关系 ,试图寻找法医学脑损伤时间的推断方法。方法　建立脑挫伤的动物模型 ,采用免疫组织化学技术 (SABC法 )观察大鼠脑挫伤后GFAP及iNOS在伤后不同时间的表达。染色结果用计算机彩色图像分析技术作定量统计分析处理。结果　 ( 1)伤后 3h时GFAP阳性表达细胞开始增多 ,1d和 5d组单个阳性细胞染色强度达峰值 ,但在 3d组相对邻近组却下降 ,呈现出一双峰波形 ,7d达最大值 ;阳性物质总面积自 3h时表达增多开始后一直增加 ,直到 7d时达高峰。 ( 2 )伤后 12h组可见iNOS活性增高 ,并随伤后存活时间的延长 ,iNOS阳性细胞数目 (或阳性物质总面积 )逐渐增多 ,单个细胞染色强度逐渐加深。伤后 1d至 3d组阳性物质总面积达到高峰 ,5d后开始下降 ,但 7d时仍维持较高水平 ;而单个细胞染色强度随伤后存活时间的延长而加深 ,于 5d时达高峰后显著下降 ,但高于起始水平。结论　脑挫伤后GFAP和iNOS在损伤局部的染色变化有一定的时间规律性 ,可以用于脑挫伤的时间推断。     

Appellate and trial court caseload growth: A pooled time-series-cross-section analysis

This is an econometric study of factors behind filing growth since 1970 in state trial courts and, especially, appellate courts. The model posits two categories of variables: those affecting the supply of disputes and those affecting the costbenefit considerations of potential litigants. The study uses a pooled time-seriescross-section design and a fixed-effects regression procedure. The overall conclusion is that factors determining the supply of disputes overwhelm other factors entered in the model. At the trial level, economic conditions 2 years earlier strongly affect civil filings, and crime rates for the current and prior year have moderate impacts on criminal filings. The output capacity of trial courts, measured by the number of judges, has a strong impact on appeals. Economic conditions and trial court filings influence civil appeals in later years, and prison commitments influence criminal appeals. The great majority of cost-benefit factors, such as simplification of appellate procedure and interest-rate differentials, showed little or no impact on appeals.In view of the rising emphasis on replicability (Dewaldet al., 1986; Campbell, 1986; Cook and Zarkin, 1986), we stress that the data for this research are available from the Inter-Univarsity consortium for Political and Social Research, and we will provide copies of the computer printouts giving the programs (that apply SAS) and the results. In addition, Court Studies periodically updates the data set, and it will supply current data upon request.     

大鼠溺死后气管纤毛变化的扫描电镜观察

应用扫描电镜对大鼠溺死后不同时间气管纤毛病理变化进行了观察，发现溺死大鼠气管纤毛局部紊乱，杯状细胞顶端开口增多，纤毛表面粘附有较多的絮网状结构．随死后时间延长，纤毛出现粘结、倒伏、结构破坏、消失等死后变化．结果表明，用扫描电镜观察上述变化有助于溺死死因诊断和死后经过时间的推断．