The Stability of 4-Chloromethcathinone in Blood and Vitreous Humor

We present results of our study on the stability of 4-chloromethcathinone (4-CMC) in authentic postmortem peripheral blood and vitreous humor samples. The stability of 4-CMC was determined in postmortem blood samples (for a period of 90 days) and vitreous humor (30 days) at three different temperatures: −15°C, +4°C, and + 23°C. The analyses were carried out using ultra-high-performance liquid chromatography coupled with triple-quadrupole tandem mass spectrometry (UHPLC-QqQ-MS/MS). In both materials, the lowest 4-CMC stability was demonstrated at room temperature. The blood samples stored in a freezer (−15°C) showed stability for the entire study period (90 days), while in the case of the vitreous humor sample stored at the same temperature the concentration of the substance decreased by 53% after 30 days. The study carried out in authentic postmortem blood and vitreous humor samples confirms the previous reports of 4-CMC instability in biological material. Authors suggest that the biological material should be stored frozen until analyses are carried out as soon as possible after collection of the material.     

Brandom on Norms and Objectivity

The aim of this paper is to investigate Brandom’s conception of the objectivity of norms. In Making It Explicit Brandom supports a weak notion of objectivity based on his understanding of the perspectival structure of linguistic practices. In his following works, he resorts to the Hegelian notion of recognition, adding a historical dimension to his account. I contend that this notion of objectivity can be successfully defended against the objections raised by the commentators. In particular, it does not jeopardise the same possibility of communication, as claimed by Habermas and others, unless a strongly objective notion of communication is assumed. However, the paradigm shift from a strong to a weak understanding of objectivity entails a consequent revision of the conception of social criticism.     

The Formal Delegation of Regulatory Decisions in the Telecommunication Sector: An Explanation Using Classification Trees

Research on regulation has traditionally focused on studying the delegation of regulatory competencies from political principals to an independent regulatory agency. In this article, we argue that this delegation is nuanced by different factors that affect whether a specific regulatory decision is formally delegated. We examine and explain formal delegation patterns at the level of individual regulatory decisions in twelve countries located in Europe, Latin America, and South Asia. The data were gathered by coding the twelve countries' telecommunications legislation. The data analysis was undertaken using a classification tree model—a nonparametric model. We found that the maturity of the market has the greatest effect on the formal delegation of regulatory decisions, but this effect is also influenced by the other theoretical factors considered, particularly the level of political constraints and the type of regulation.     

The Space Between: Demonization of Opponents and Policy Divergence

Prior research on policy conflicts indicates a tendency among policy actors to misperceive the influence of actors engaged in policy debates based on the degree of distance between their relative policy positions. This research develops a measure for assessing the degree and direction of the misperception effect. This measure is then utilized as a dependent variable to assess the relationship between theoretically relevant factors and the degree to which actors will exaggerate the influence of their opponents and allies. The research uses original survey data of policy actors engaged in the debate over hydraulic fracturing in New York. The results indicate misperceptions of relative influence are prevalent and most associated with the experience of a policy loss and holding relatively extreme policy beliefs. The findings provide new insight into factors that influence the demonization of political opponents. These insights are timely in the context of polarized debates over environmental and energy policy in the United States.     

How representative are brics?

The five countries known as brics, while not homogeneous in interests, values, and policy preferences, do have a common interest in checking US/Western power and influence through collaboration with non-Western powers. They vary considerably but all are ahead of other developing countries on population, military power, economic weight, geopolitical clout, and global reach and engagement. They are unrepresentative of the typical developing country in terms of interest, capacity, and resources, but they can represent the interests and goals of developing countries as a group on those issues for which the North–South division is salient. The diversity within brics, their differences from other developing countries, and their potential to reflect and represent the global South are explored with respect to climate change, finance, trade, aid, human rights and intervention, and development. It remains unclear whether brics can morph from a countervailing economic grouping to a powerful political alternative.     

以“4+3”管理手段为载体 探索采油厂基层队内部市场管理新途径

大庆油田有限责任公司第三采油厂在基层单位运用市场手段,探索实施"4+3"内部市场管理法。"4+3",即构建4个内部模拟市场,完善三项配套措施。实行"4+3"内部市场化管理模式两年来,基层队发生了深刻变化:员工自觉性明显提高;员工学习技术热情明显提高;员工挖潜增效意识明显提高;基层生产管理水平明显提高。     

性别视野中的女学生之死——以五四时期李超为中心

北京女子高等师范学校学生李超为争取平等的教育权,与传统家庭不断抗争,不幸病死.这一悲剧经由追悼会、媒体报道逐渐转化成一起公共事件,引发有关妇女命运及其解放的热烈讨论,并由此产生多种文本.而文本制造者的不同性别、身份又导致各自论述中存在某些差异.李超事件的发生,呈现出五四时期社会性别关系的复杂面貌.在诉诸于制度变革之外,妇女解放仍需要女性自主意识的觉醒和女性力量的增强.     

云南省11个民族腺苷脱氨酶(ADA)频率的分布调查

采用电泳技术对云南省汉、彝、自、傣、哈尼、瑶、布朗、基诺、拉祜、佤及苦聪等11个民族的ADA 进行了表型分布调查。并对-20℃、4℃、室温(20℃左右)保存的血痕ADA 活性进行了测定。在汉族人群中发现了一例ADA4-1稀有型,家系调查表明其是由父亲遗传下来的。     

损伤皮肤中白三烯B_4含量测定与损伤时间推断

本文作者利用高压液相色谱,快速检测大鼠皮肤切创创缘组织中白三烯B_4含量。结果发现,生前各损伤时间组创缘中白三烯B_4含量明显升高,且在1小时内与损伤时间有一定线性关系;死后损伤标本未见白三烯B_4含量升高。由此表明白三烯B_4含量测定,对推断生前1小时内的损伤时间有重要价值。高压液相色谱能快速、准确地检测损伤组织中的白三烯B_4。