心肌早期缺血再灌流损伤免疫组化观察

探询原癌基因c fos蛋白产物在心肌早期缺血再灌流损伤中的病理形态学改变。用SD大白鼠建立心肌早期缺血再灌流损伤模型 ,3 2只大鼠分为正常、缺血对照组与缺血再灌流组。心脏标本经HE染色及免疫组化观察。结果发现 :在缺血 3 0min再灌流 3 0min后 ,再灌流区心肌细胞有部分细胞核 ( 3 7 76%± 9 66% )呈弱阳性着色 ,而在缺血 60min再灌流 3 0min后 ,心肌细胞核 ( 4 0 3 4 %± 3 3 2 % )呈棕褐色阳性染色 ,但正常和单纯缺血组心肌细胞核未见有阳性反应 ;HE染色无明显改变。提示c fos蛋白免疫组化对显示实验性心肌早期缺血再灌流损伤有重要的价值     

Early detection and early intervention in prison: improving outcomes and reducing prison returns

Our aim was to investigate whether early detection was feasible in prison and whether it could improve mental health outcomes in young prisoners. A secondary aim was to explore whether it can reduce returns to prison. Between 2011 and 2014, a total of 2115 young prisoners were screened, 94 (4.4%) met criteria for ultra-high risk for psychosis and were offered an intervention, 52 actually received it. Return to prison data were sought on the 52 participants, receiving a formal intervention. Of the 52 prisoners who received an intervention, 30.8% returned to custody compared to national average reconviction rates of between 45.4 and 66.5%. Our results suggest that early detection is a feasible option in a prison setting, improving mental health outcomes and reducing returns to prison. Mental health outcomes were recorded for a sub-sample of those receiving the intervention. The results indicated statistically significant improvements on measures of depression, anxiety and psychological distress.     

论西周至春秋中晚期"士"的社会身份之发展演变--兼论《诗经》中士的生存状态

早期“士”首先由殷周之际较有权势的上层贵族,一变而成为周代礼乐制度规定下的低级贵族。同时,随着作为礼乐制度核心的宗法世袭制的动摇和封建制的逐渐崩溃。这一阶层在春秋中叶以后再次发生蜕变,并渐与庶人合流,形成一个新兴阶层。并在更为深远的意义上最终促进了以儒家为代表的中国传统知识分子的形成。     

中国古代刑法中的“罪刑法定”论

在中国古代刑法中,很早就有了"罪刑法定"的思想.这一思想从春秋时期被提出,经战国、秦汉的发展,遭"春秋决狱"的磨难,到晋代的再次被提出和隋唐的进一步发展及以后各代的相继沿用,前后经历了漫长的历程.但是,由于中国封建专制皇权的存在,"罪刑法定"思想始终没能上升为古代刑法的基本原则.尽管如此,"罪刑法定"思想在同罪刑擅断相斗争,维护封建统治的过程中,一直发挥着重要的作用.     

国内群体性突发事件预警研究

区域性群体性突发事件预警是预测心理学研究重点之一,目前国内外学术界已开展了与群体性突发事件预警相关的“社会指数”研究和关于国内群体性突发事件预警的实证性研究。作为基础和前提,对国内群体性突发事件预警问题开展的研究应建立适当的模型,设定相应的指标体系并遵循科学的步骤。准确把握研究国内群体性突发事件预警内容的目的,在于指导政府面对群体性突发事件时采取科学有效的危机管理行为。     

From Ahogado to Zorrillo: external causes of mortality in the California missions

The history of grandparents is too often founded on a demographic prejudice, that is, the very low statistical possibility of children having known their grandparents before the rise in life expectancy in the twentieth century. On the basis of a sample of several thousand children bom in the region of Vernon (Normandy) at the end of the eighteenth and the beginning of the nineteenth century, the article contests this idea and shows that newborns knew about half of their grandparents, with a slight advantage on the grandmothers' side. Inequalities were present between elder and younger siblings, but the latter also profited from the presence of their forbears. Consequently, the study of the different functions served by grandparents in the traditional family should be pursued, and questions should be raised about the contemporary concept of “new grandparents” by separating it from the demographic assumption on which it is based.     

Keeping children safe in nurseries: A focus on culture and context

Abstract

There have been few reported incidents of sexual abuse within nurseries until recently, when abuse has come to light as a result of investigations into online sexual offending. This paper uses information from serious case reviews to compare two of these incidents with a view to understanding the factors that might contribute to abuse taking place within nurseries. Information from the reviews points to the context and culture of the nursery environment being of key importance, particularly the degree to which relationships and the emotional health of the setting allow the offender to assume a position of power within the group. This has implications for the way in which nurseries are managed and regulated.     

Survival strategies of widows and their families in early modern Holland,c. 1580–1750

This article analyses the impact of widowhood upon women in early modern urban society in Holland. Widows were able to maintain their households and to minimize the discontinuity with their lives when married. A remarkably egalitarian inheritance and marital property law, access to a broad range of occupations, a privileged status, an extended poor relief system, institutionalised mutual assistance and new forms of financial provisions for widows enabled widows to survive after the loss of an adult male breadwinner. However, legal rights, social provisions and economic opportunities available to women in the Dutch Golden Age and thereafter, could not prevent social polarization after women lost their spouse.     

The legal possibilities of Antwerp widows in the late sixteenth century

This article assesses the ability of widows and other women in Antwerp to act independently of men to defend their economic interests and those of their children. Consideration is given to both legal norms and actual practice in a number of different areas including writing wills, making marriage contracts, managing financial assets and pursuing claims and defending themselves in the civil courts. Analyses of these issues indicate that widows in Antwerp enjoyed in practice a greater degree of independence than was available to widows in many other parts of Europe, despite their weaker position in law.

Particular attention is given to the role in Antwerp of women merchants whose position freed them from male control and supervision. It is argued that their favored status did not derive from the desire of the authorities to protect the interests of their male relatives or to advance the economic interests of these women. Rather their legal freedom is seen as reflecting acknowledgement of the importance of their business activities and the wish to safeguard the interests of their customers who could pursue claims against the woman merchant in the event of a dispute.